Neurostructural subgroup in 4291 individuals with schizophrenia identified using the subtype and stage inference algorithm

Autor: Yuchao Jiang, Cheng Luo, Jijun Wang, Lena Palaniyappan, Xiao Chang, Shitong Xiang, Jie Zhang, Mingjun Duan, Huan Huang, Christian Gaser, Kiyotaka Nemoto, Kenichiro Miura, Ryota Hashimoto, Lars T. Westlye, Genevieve Richard, Sara Fernandez-Cabello, Nadine Parker, Ole A. Andreassen, Tilo Kircher, Igor Nenadić, Frederike Stein, Florian Thomas-Odenthal, Lea Teutenberg, Paula Usemann, Udo Dannlowski, Tim Hahn, Dominik Grotegerd, Susanne Meinert, Rebekka Lencer, Yingying Tang, Tianhong Zhang, Chunbo Li, Weihua Yue, Yuyanan Zhang, Xin Yu, Enpeng Zhou, Ching-Po Lin, Shih-Jen Tsai, Amanda L. Rodrigue, David Glahn, Godfrey Pearlson, John Blangero, Andriana Karuk, Edith Pomarol-Clotet, Raymond Salvador, Paola Fuentes-Claramonte, María Ángeles Garcia-León, Gianfranco Spalletta, Fabrizio Piras, Daniela Vecchio, Nerisa Banaj, Jingliang Cheng, Zhening Liu, Jie Yang, Ali Saffet Gonul, Ozgul Uslu, Birce Begum Burhanoglu, Aslihan Uyar Demir, Kelly Rootes-Murdy, Vince D. Calhoun, Kang Sim, Melissa Green, Yann Quidé, Young Chul Chung, Woo-Sung Kim, Scott R. Sponheim, Caroline Demro, Ian S. Ramsay, Felice Iasevoli, Andrea de Bartolomeis, Annarita Barone, Mariateresa Ciccarelli, Arturo Brunetti, Sirio Cocozza, Giuseppe Pontillo, Mario Tranfa, Min Tae M. Park, Matthias Kirschner, Foivos Georgiadis, Stefan Kaiser, Tamsyn E. Van Rheenen, Susan L. Rossell, Matthew Hughes, William Woods, Sean P. Carruthers, Philip Sumner, Elysha Ringin, Filip Spaniel, Antonin Skoch, David Tomecek, Philipp Homan, Stephanie Homan, Wolfgang Omlor, Giacomo Cecere, Dana D. Nguyen, Adrian Preda, Sophia I. Thomopoulos, Neda Jahanshad, Long-Biao Cui, Dezhong Yao, Paul M. Thompson, Jessica A. Turner, Theo G. M. van Erp, Wei Cheng, ENIGMA Schizophrenia Consortium, Jianfeng Feng, ZIB Consortium

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract Machine learning can be used to define subtypes of psychiatric conditions based on shared biological foundations of mental disorders. Here we analyzed cross-sectional brain images from 4,222 individuals with schizophrenia and 7038 healthy su

Externí odkaz: https://doaj.org/article/76bdd81832814fb8a0f1d01e09c35de4

Crimean-Congo hemorrhagic fever cases diagnosed during an outbreak of Sudan virus disease in Uganda, 2022-23.

Autor: Stephen Balinandi, Sophia Mulei, Shannon Whitmer, Luke Nyakarahuka, Caitlin M Cossaboom, Elizabeth Shedroff, Maria Morales-Betoulle, Inna Krapiunaya, Alex Tumusiime, Jackson Kyondo, Jimmy Baluku, Dianah Namanya, Calvin R Torach, Joanita Mutesi, Jocelyn Kiconco, Godfrey Pimundu, Tonny Muyigi, Jessica Rowland, Andrew Nsawotebba, Isaac Ssewanyana, David Muwanguzi, Daniel Kadobera, Julie R Harris, Alex R Ario, Kagirita Atek, Henry B Kyobe, Susan Nabadda, Pontiano Kaleebu, Henry G Mwebesa, Joel M Montgomery, Trevor R Shoemaker, Julius J Lutwama, John D Klena

Publikováno v: PLoS Neglected Tropical Diseases, Vol 18, Iss 10, p e0012595 (2024)

BackgroundIn September 2022, Uganda experienced an outbreak of Sudan virus disease (SVD), mainly in central Uganda. As a result of enhanced surveillance activities for Ebola disease, samples from several patients with suspected viral hemorrhagic feve

Externí odkaz: https://doaj.org/article/d62dfefe45454da6921ea5912f98ff7a

The clinical utility of cystatin C based eGFR in assessing renal function among HIV/AIDs patients on ART at Mildmay Uganda

Autor: Enock Wekiya, Godfrey P. Mujuzi, Jane Nakiyingi, Juliet Sanya, Moses Matovu, Ocung Guido, Jane Nakaweesi, Charles Karamagi, Joan K. Nakayaga, Edrisa I. Mutebi, Damalie Nakanjako

Publikováno v: BMC Nephrology, Vol 25, Iss 1, Pp 1-7 (2024)

Abstract Background In clinical practice, Measurement of estimated glomerular filtration rates (eGFR) is the gold standard assessing renal function the glomerular filtration rate often estimated from plasma creatinine. Several studies have shown Cyst

Externí odkaz: https://doaj.org/article/c0f3f0cfa7fd499f95780bc5f8e5315e

A confounder controlled machine learning approach: Group analysis and classification of schizophrenia and Alzheimer's disease using resting-state functional network connectivity.

Autor: Reihaneh Hassanzadeh, Anees Abrol, Godfrey Pearlson, Jessica A Turner, Vince D Calhoun

Publikováno v: PLoS ONE, Vol 19, Iss 5, p e0293053 (2024)

Resting-state functional magnetic resonance imaging (rs-fMRI) has increasingly been used to study both Alzheimer's disease (AD) and schizophrenia (SZ). While most rs-fMRI studies being conducted in AD and SZ compare patients to healthy controls, it i

Externí odkaz: https://doaj.org/article/21da186a8d63427a81d42ff71d1d676a

Regional Evaluation of Two SARS-CoV-2 Antigen Rapid Diagnostic Tests in East Africa

Autor: Muna Affara, Hakim Idris Lagu, Emmanuel Achol, Neema Omari, Grace Ochido, Eric Kezakarayagwa, Francine Kabatesi, Cassien Nduwimana, Anatole Nkeshimana, Donald Duku Samson, Gwokpan Awin Nykwec, Joseph Daniel Wani Lako, Michael Lasuba, Lul Lojok Deng, Maria Ezekiely Kelly, Peter Bernard Mtesigwa Mkama, Alex Magesa, Salum Said Ali, Sabra Amour Rashid, Godfrey Pimundu, Tonny Muyigi, Susan Ndidde Nabadda, Robert Rutayisire, Alice Kabanda, Emmanuel Kabalisa, Jürgen May, Eric Nzeyimana, Michael Katende, Florian Gehre

Publikováno v: Microbiology Spectrum, Vol 11, Iss 3 (2023)

ABSTRACT The clinical performance of two rapid antigen tests for the diagnosis of Severe Acute Respiratory Coronavirus (SARS-CoV-2) were regionally evaluated in East African populations. Swabs were collected from 1,432 individuals from five Partner S

Externí odkaz: https://doaj.org/article/c5fe2145bb0c4a819de1f2b9851d81fc