Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Godfrey Mayoka"'
Autor:
Ameera Mohammed Dawoodjee, John Sichinga, Harrison Banda, Steve Mbaya, Evelyn Funjika, Godfrey Mayoka, Christabel Hikaambo, Karol R. Francisco, Yujie Uli Sun, Lawrence J. Liu, Conor R. Caffrey, Peter Mubanga Cheuka
Publikováno v:
Results in Chemistry, Vol 12, Iss , Pp 101890- (2024)
For the adult Schistosoma mansoni flatworm pathogen, we report further structure activity relationships (SAR) of 19 N-phenylbenzamide analogs. Our previous SAR studies, designed by selecting representative substituents from the Craig plot, identified
Externí odkaz:
https://doaj.org/article/79d0dd0602cc48f4b4d7c306a5f0ed47
Autor:
Steward Mudenda, Victor Daka, Webrod Mufwambi, Scott Kaba Matafwali, Billy Chabalenge, Phumzile Skosana, Ruth Lindizyani Mfune, Maisa Kasanga, Osaretin Christabel Okonji, Godfrey Mayoka, Martin Kampamba, Christabel Nang’andu Hikaambo, Moses Mukosha, Manal Hadi Ghaffoori Kanaan, Lindi Angeline Zikalala-Mabope, George Sinkamba, Roland Nnaemeka Okoro, Martha Chulu, Brian Godman, Joseph Fadare
Publikováno v:
SAGE Open Medicine, Vol 11 (2023)
Objectives: The coronavirus disease 2019 (COVID-19) pandemic disrupted classroom-based learning, necessitating the adoption of online learning in most universities. However, there has been a lack of information on university students’ perspectives
Externí odkaz:
https://doaj.org/article/90c887f78a724b13870f6477ed5f2691
Autor:
Steward Mudenda, Nelly Ngalande, Moses Mukosha, Christabel Nang'andu Hikaambo, Victor Daka, Scott Kaba Matafwali, Michelo Banda, Ruth Lindizyani Mfune, Godfrey Mayoka, Bwalya Angel Witika
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
BackgroundThe COVID-19 pandemic led to the disruption of physical classes for university students globally, as large gatherings fuelled the transmission of the virus. In the efforts to mitigate its transmission and return to normality, prevention mea
Externí odkaz:
https://doaj.org/article/d9da850af52d41468dd85f0629fa42d2
Publikováno v:
Molecules, Vol 22, Iss 1, p 58 (2016)
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect more than 1 billion people annually, including 875 million children in developing economies. These diseases are also responsible for over 500,000 deaths per
Externí odkaz:
https://doaj.org/article/37947e461f15458d816b43043d2ffd69
Publikováno v:
Current Topics in Medicinal Chemistry. 23:227-247
Background: The downward trend in malaria cases and deaths is steadily reversed - 627,000 deaths in 2020 compared to 405,000 deaths in 2018. Drug resistance has compromised the effectiveness of currently available treatment options, with some reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d731dd5eb850d9dd4603d566f07e347
https://doi.org/10.2174/1568026623666221220140526
https://doi.org/10.2174/1568026623666221220140526
Autor:
Christabel Nang’andu Hikaambo, Phanuel Chilala, Ferdinand Ndubi, Godfrey Mayoka, Martin Kampamba, Reagan Kabuka, Billy Chabalenge, Steward Mudenda
Publikováno v:
Pharmacology & Pharmacy. 14:176-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194b090aa814059057e3ef5f16f53b51
https://doi.org/10.4236/pp.2023.145013
https://doi.org/10.4236/pp.2023.145013
Numerous limitations encountered with mainstream Western Medicine, including exorbitant costs, side effects, ineffectiveness and unavailability continue to endear many to alternative herbal therapies. The World Health Organization recognizes the ramp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4d97d23ff29a4bd961684b15c03ee7
https://zenodo.org/record/8116550
https://zenodo.org/record/8116550
Autor:
Godfrey Mayoka, Peter Mubanga Cheuka
Pharmacological benefits of herbal interventions are incontestable and there is widespread use of traditional and alternative medicine across disease conditions and socioeconomic status, on the African continent. While the efficacy of some treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27101c8e74fcb979ddf654336ef48129
https://zenodo.org/record/8116327
https://zenodo.org/record/8116327
Publikováno v:
Trends in Parasitology. 38:719-721
Inhibiting translation presents a tantalizing strategy to tackle the most virulent human malaria parasite. Xie et al. disclose a compound that binds selectively to Plasmodium falciparum tyrosine aminoacyl-tRNA synthetase, preventing the incorporation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d26697b35981b9d4c1df371cf4fa2b
https://doi.org/10.1016/j.pt.2022.07.001
https://doi.org/10.1016/j.pt.2022.07.001
Autor:
Lyn-Marie Birkholtz, Sergio Wittlin, Liezl Gibhard, Sonja B Lauterbach, Janette Reader, John Okombo, Theresa L. Coetzer, Clive Yeates, Godfrey Mayoka, Diana Fontinha, Alisje Churchyard, Kelly Chibale, Miguel Prudêncio, Timothy J. Egan, Belinda C. Bezuidenhout, Mariëtte van der Watt, Mathew Njoroge, Margarida Sanches-Vaz
Publikováno v:
Journal of Medicinal Chemistry. 62:1022-1035
Structure-activity relationship studies involving N-aryl-3-trifluoromethyl pyrido[1,2- a]benzimidazoles (PBI) identified several compounds possessing potent in vitro activities against the asexual blood, liver, and gametocyte stages of the Plasmodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c4e2cbcbdc81b7f785d4671e9620ad
https://doi.org/10.1021/acs.jmedchem.8b01769
https://doi.org/10.1021/acs.jmedchem.8b01769