Electrophysiological studies of malaria parasite-infected erythrocytes: Current status

Autor: Patrick Verloo, Ajay Pillai, Henry M. Staines, Abdulnaser Alkhalil, Sanjay A. Desai, Florian Lang, Richard J.W. Allen, Serge Thomas, Sherin J. Rouhani, Kempaiah Rayavara, Kevin J. Saliba, Eugene K. Oteng, Hugo R. de Jonge, Elvira T. Derbyshire, Kiaran Kirk, Godfrey Lisk, Stéphane Egée, Tsione Solomon, Stephan M. Huber, Hagai Ginsburg, David R.C. Hill, Crystal Shen

Publikováno v: International Journal for Parasitology
International Journal for Parasitology, Elsevier, 2007, 37 (5), pp.475-82. ⟨10.1016/j.ijpara.2006.12.013⟩
International Journal for Parasitology, 2007, 37 (5), pp.475-82. ⟨10.1016/j.ijpara.2006.12.013⟩
International Journal for Parasitology, 37(5), 475-482. Elsevier Ltd.

International audience; The altered permeability characteristics of erythrocytes infected with malaria parasites have been a source of interest for over 30 years. Recent electrophysiological studies have provided strong evidence that these changes re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03aaaffa010efd759ac00f0ee272eb13
https://doi.org/10.1016/j.ijpara.2006.12.013

Specific Inhibition of the Plasmodial Surface Anion Channel by Dantrolene

Autor: Jamieson V. Cohn, Sanjay A. Desai, Godfrey Lisk, Myungsa Kang

Publikováno v: Eukaryotic Cell. 5:1882-1893

The plasmodial surface anion channel (PSAC), induced on human erythrocytes by the malaria parasite Plasmodium falciparum , is an important target for antimalarial drug development because it may contribute to parasite nutrient acquisition. However, k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373fbfe3a7f634bec04c4ab021db9860
https://doi.org/10.1128/ec.00212-06

Evaluation of the Therapeutic Usefulness of Botulinum Neurotoxin B, C1, E, and F Compared with the Long Lasting Type A

Autor: Godfrey Lisk, Patrick G. Foran, Leonard A. Smith, Gary W. Lawrence, Sharuna Nagwaney, K. Roger Aoki, Eric N. Johnson, Nadiem Mohammed, J. Oliver Dolly

Publikováno v: Journal of Biological Chemistry. 278:1363-1371

Seven types (A–G) of botulinum neurotoxin (BoNT) target peripheral cholinergic neurons where they selectively proteolyze SNAP-25 (BoNT/A, BoNT/C1, and BoNT/E), syntaxin1 (BoNT/C1), and synaptobrevin (BoNT/B, BoNT/D, BoNT/F, and BoNT/G), SNARE prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1a773edca3e08f6fad98679071ddb5a
https://doi.org/10.1074/jbc.m209821200

Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes

Autor: Michael P. Fay, Margaret Pain, Tetsuya Furuya, Sanjay A. Desai, Xin-zhuan Su, Godfrey Lisk, Shivkumar Kambhampati, Daniel E. Goldberg, Ilya Y. Gluzman

Publikováno v: Antimicrobial agents and chemotherapy. 52(7)

Cysteine protease inhibitors kill malaria parasites and are being pursued for development as antimalarial agents. Because they have multiple targets within bloodstream-stage parasites, workers have assumed that resistance to these inhibitors would no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c4df774cfdc4fe005c7e19332a9a67
https://pubmed.ncbi.nlm.nih.gov/18443109

The plasmodial surface anion channel is functionally conserved in divergent malaria parasites

Autor: Sanjay A. Desai, Godfrey Lisk

Publikováno v: Eukaryotic cell. 4(12)

The plasmodial surface anion channel (PSAC), a novel ion channel induced on human erythrocytes infected with Plasmodium falciparum , mediates increased permeability to nutrients and presumably supports intracellular parasite growth. Isotope flux stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ae947d7ce9e6a20a1d15d757b0e333
https://pubmed.ncbi.nlm.nih.gov/16339732