Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Godfred Eyiah-Mensah"'
Autor:
Thuy L. Phung, Rita A. Monahan-Earley, Kenneth Walsh, Michelle I. Lin, Godfred Eyiah-Mensah, Michal Neeman, Harold F. Dvorak, Carole A. Perruzzi, Jingfang Sun, Donnette Dabydeen, Keren Ziv, Laura E. Benjamin, William C. Sessa, Ann M. Dvorak, Marcela Riveros, Janice A. Nagy, Ichiro Shiojima, David M. Briscoe
Publikováno v:
Cancer Cell. 10:159-170
SummaryEndothelial cells in growing tumors express activated Akt, which when modeled by transgenic endothelial expression of myrAkt1 was sufficient to recapitulate the abnormal structural and functional features of tumor blood vessels in nontumor tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed52baf1b03c24b982247345fbc60940
https://doi.org/10.1016/j.ccr.2006.07.003
https://doi.org/10.1016/j.ccr.2006.07.003
Autor:
Kenneth Walsh, Radoslaw Bieniek, Charlotte Kuperwasser, Godfred Eyiah-Mensah, Thuy L. Phung, Laura E. Benjamin, Rebekah K. O'Donnell, Sharon Shechter
Chronic activation of Akt signaling in the endothelium recapitulates the salient features of a tumor vasculature and can be inhibited by rapamycin, an inhibitor of mammalian target of rapamycin. This led to the hypothesis that the antitumor efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e309b688666b32460bd90a6f4875f3eb
https://europepmc.org/articles/PMC2396346/
https://europepmc.org/articles/PMC2396346/
