Nystagmus in patients with congenital stationary night blindness (CSNB) originates from synchronously firing retinal ganglion cells.

Autor: Beerend H J Winkelman, Marcus H C Howlett, Maj-Britt Hölzel, Coen Joling, Kathryn H Fransen, Gobinda Pangeni, Sander Kamermans, Hiraki Sakuta, Masaharu Noda, Huibert J Simonsz, Maureen A McCall, Chris I De Zeeuw, Maarten Kamermans

Publikováno v: PLoS Biology, Vol 17, Iss 9, p e3000174 (2019)

Congenital nystagmus, involuntary oscillating small eye movements, is commonly thought to originate from aberrant interactions between brainstem nuclei and foveal cortical pathways. Here, we investigated whether nystagmus associated with congenital s

Externí odkaz: https://doaj.org/article/4bd424b2c43d473381e2104f3c3183ab

The spatial properties of L- and M-cone inputs to electroretinograms that reflect different types of post-receptoral processing.

Autor: Mellina M Jacob, Gobinda Pangeni, Bruno D Gomes, Givago S Souza, Manoel da Silva Filho, Luiz Carlos L Silveira, John Maguire, Neil R A Parry, Declan J McKeefry, Jan Kremers

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121218 (2015)

We studied the spatial arrangement of L- and M-cone driven electroretinograms (ERGs) reflecting the activity of magno- and parvocellular pathways. L- and M-cone isolating sine wave stimuli were created with a four primary LED stimulator using triple

Externí odkaz: https://doaj.org/article/0f4f8caa98234f05902ee8fbde810fd3

A missense mutation in Grm6 reduces but does not eliminate mGluR6 expression or rod depolarizing bipolar cell function

Autor: Ronald G. Gregg, Gobinda Pangeni, Laura G. Reinholdt, Neal S. Peachey, Samantha Burrill, Son Yong Karst, Bernard FitzMaurice, Maureen A. McCall, Nazarul Hasan, Marge Strobel, Melissa L. Berry, Bo Chang

Publikováno v: Journal of Neurophysiology. 118:845-854

This article describes a mouse model of the human disease complete congenital stationary night blindness in which the mutation reduces but does not eliminate GRM6 expression and bipolar cell function, a phenotype distinct from that seen in other Grm6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5d4572a8c2231c03ac04eec79477c38
https://doi.org/10.1152/jn.00888.2016

Nystagmus in patients with congenital stationary night blindness (CSNB) originates from synchronously firing retinal ganglion cells

Autor: Maj-Britt Hölzel, Masaharu Noda, Hiraki Sakuta, Gobinda Pangeni, Huibert J. Simonsz, Sander Kamermans, Kathryn H. Fransen, Chris I. De Zeeuw, Maureen A. McCall, Coen Joling, Maarten Kamermans, Marcus H. C. Howlett, Beerend H. J. Winkelman

Publikováno v: PLoS Biology (print), 17(9):e3000174. Public Library of Science
PLoS Biology, 17(9). Public Library of Science
PLoS Biology
PLoS biology, 17(9). Public Library of Science
PLOS Biology
PLoS Biology, Vol 17, Iss 9, p e3000174 (2019)

Congenital nystagmus, involuntary oscillating small eye movements, is commonly thought to originate from aberrant interactions between brainstem nuclei and foveal cortical pathways. Here, we investigated whether nystagmus associated with congenital s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2ecf78c0c628db9fc0771484d362fe
https://pure.eur.nl/en/publications/358630c6-1db2-46c8-b0c9-b7ec1a8f282b

Presynaptic LRIT3 Expression Trans-Synaptically Organizes Postsynaptic Trafficking of TRPM1 in Rod Bipolar Cells and Restores Vision in Dim Light

Autor: Thomas A. Ray, Catherine Cobb, Maureen A. McCall, Daniel M. Lipinski, Gobinda Pangeni, Ronald G. Gregg, Emily R. Nettesheim, Nazarul Hasan, Kristina J. Ertel

Publikováno v: SSRN Electronic Journal.

Synaptic function requires the precise alignment of pre and post-synaptic signaling complexes. At the first synapse in the retina, each rod photoreceptor connects via an invaginating ribbon synapse to two postsynaptic partners, rod bipolar cells (RBC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::700020a59cbee8f276e4826f814a277b
https://doi.org/10.2139/ssrn.3276047