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Akademický článek

Comparison of measures of marker informativeness for ancestry and admixture mapping

Autor: Ding Lili, Wiener Howard, Abebe Tilahun, Altaye Mekbib, Go Rodney CP, Kercsmar Carolyn, Grabowski Greg, Martin Lisa J, Khurana Hershey Gurjit K, Chakorborty Ranajit, Baye Tesfaye M

Publikováno v: BMC Genomics, Vol 12, Iss 1, p 622 (2011)

Abstract Background Admixture mapping is a powerful gene mapping approach for an admixed population formed from ancestral populations with different allele frequencies. The power of this method relies on the ability of ancestry informative markers (A

Externí odkaz: https://doaj.org/article/173181069cc2453e9e92b49e9c6abb98

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Akademický článek

Database mining for selection of SNP markers useful in admixture mapping

Autor: Baye Tesfaye M, Tiwari Hemant K, Allison David B, Go Rodney C

Publikováno v: BioData Mining, Vol 2, Iss 1, p 1 (2009)

Abstract Background New technologies make it possible for the first time to genotype hundreds of thousands of SNPs simultaneously. A wealth of genomic information in the form of publicly available databases is underutilized as a potential resource fo

Externí odkaz: https://doaj.org/article/f51b6ea197424e9282c0fee870fdbc4a

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Akademický článek

Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?

Autor: Okoli Joel, Carey Delicia, Khan Masood, Aikhionbare Felix O, Go Rodney

Publikováno v: Molecular Cancer, Vol 3, Iss 1, p 30 (2004)

Abstract To examine the relationship between mitochondrial DNA (mtDNA) alterations and colorectal tumorigenesis, we used high-resolution restriction endonucleases and sequencing to assess the mitochondrial genome from three histologic subtypes of col

Externí odkaz: https://doaj.org/article/ba55a50057594861a7444e5c2c7d6c23

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Akademický článek

Ancestry reported by white adults with cutaneous melanoma and control subjects in central Alabama

Autor: Hollowell William W, Barton Ellen H, Acton Ronald T, Dreibelbis Amy L, Go Rodney CP, Barton James C

Publikováno v: BMC Cancer, Vol 4, Iss 1, p 47 (2004)

Abstract Background We sought to evaluate the hypothesis that the high incidence of cutaneous melanoma in white persons in central Alabama is associated with a predominance of Irish and Scots descent. Methods Frequencies of country of ancestry report

Externí odkaz: https://doaj.org/article/5b4d7b8ea7054f198e97f59c09f6a2ed

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