Zobrazeno 1 - 10
of 440
pro vyhledávání: '"Göran Widmalm"'
Autor:
Göran Widmalm
Publikováno v:
JACS Au, Vol 4, Iss 1, Pp 20-39 (2024)
Externí odkaz:
https://doaj.org/article/6373bf9b07b941ca87a0bbb10d8f8fd3
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Lipopolysaccharides such as the enterobacterial common antigen are important components of the enterobacterial cell envelope that act as a protective barrier against the environment and are often polymerized by the inner membrane bound Wzy-d
Externí odkaz:
https://doaj.org/article/14d2860152484fb4adc21aa78b12d129
Autor:
Jeffrey S. Rush, Prakash Parajuli, Alessandro Ruda, Jian Li, Amol Arunrao Pohane, Svetlana Zamakhaeva, Mohammad M. Rahman, Jennifer C. Chang, Artemis Gogos, Cameron W. Kenner, Gérard Lambeau, Michael J. Federle, Konstantin V. Korotkov, Göran Widmalm, Natalia Korotkova
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The cell wall of the bacterial pathogen Group A Streptococcus is decorated with a polysaccharide termed GAC, which is a target for vaccine development. Here, Rush et al. characterize the linkage between GAC and peptidoglycan, and identify a protein t
Externí odkaz:
https://doaj.org/article/130eebb1fa99400f96845c5523f18f64
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 1892-1897 (2021)
Externí odkaz:
https://doaj.org/article/4dbd6a8574d44c318209bc6098f1f8cd
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Lipopolysaccharides, important components of the bacterial cell envelope, are synthesized at the inner membrane by the Wzx/Wzy-dependent assembly pathway. A cryo-EM structure of an intact E. coli WzzB, the polysaccharide co-polymerase component of th
Externí odkaz:
https://doaj.org/article/1ee44a4ef17c4cc6a456eb3b1384aa08
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 79-88 (2020)
A lipopolysaccharide (LPS) molecule is a key component of the bacterial outer membrane used to protect the bacterium and to interact with the environment. To gain insight into its function, the study of the LPS conformation and dynamics at the molecu
Externí odkaz:
https://doaj.org/article/4f1e57a2f4dc465f94588c26c9aa00cf
Autor:
Lars Eriksson, Göran Widmalm
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 75, Iss 6, Pp 854-857 (2019)
The title compound, C13H24O9·H2O, a structural model for part of bacterial O-antigen polysaccharides from Shigella flexneri and Escherichia coli, crystallizes with four independent disaccharide molecules and four water molecules in the asymmetric un
Externí odkaz:
https://doaj.org/article/03352148f4d04325bcbdf08e07763c9e
Autor:
Federico Riu, Alessandro Ruda, Roberta Ibba, Simona Sestito, Ilenia Lupinu, Sandra Piras, Göran Widmalm, Antonio Carta
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 942 (2022)
Certain bacteria constitute a threat to humans due to their ability to escape host defenses as they easily develop drug resistance. Bacteria are classified into gram-positive and gram-negative according to the composition of the cell membrane structu
Externí odkaz:
https://doaj.org/article/f8dc503de5c04460bc330b27994a5d89
Autor:
Federico Riu, Alessandro Ruda, Olof Engström, Claudio Muheim, Hani Mobarak, Jonas Ståhle, Paul Kosma, Antonio Carta, Daniel O. Daley, Göran Widmalm
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 209 (2022)
Glucosyl transferase I (WaaG) in E. coli catalyzes the transfer of an α-d-glucosyl group to the inner core of the lipopolysaccharide (LPS) and plays an important role in the biogenesis of the outer membrane. If its activity could be inhibited, the i
Externí odkaz:
https://doaj.org/article/cd1f7434b9224174af3b332aa26cca7c
Autor:
Estrella Martínez-Gómez, Jonas Ståhle, Yolanda Gil-Ramírez, Amaia Zúñiga-Ripa, Mona Zaccheus, Ignacio Moriyón, Maite Iriarte, Göran Widmalm, Raquel Conde-Álvarez
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Brucellosis is a bacterial zoonosis of worldwide distribution caused by bacteria of the genus Brucella. In Brucella abortus and Brucella melitensis, the major species infecting domestic ruminants, the smooth lipopolysaccharide (S-LPS) is a virulence
Externí odkaz:
https://doaj.org/article/e5f59a7c8f304576ad366894bd0055a4