Zobrazeno 1 - 10
of 438
pro vyhledávání: '"Göran K. Hansson"'
Autor:
Katarina Wadén, Eva Karlöf, Sampath Narayanan, Mariette Lengquist, Göran K. Hansson, Ulf Hedin, Joy Roy, Ljubica Matic
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104219- (2022)
Summary: Unstable carotid stenosis is an important cause of ischemic stroke, yet the basis of disease pathophysiology remains largely unknown. We hypothesized that integrated analyses of symptomatic carotid stenosis patients at increased stroke risk
Externí odkaz:
https://doaj.org/article/8307a2ba29fc4cb3a9474a704d3de232
Autor:
Xintong Jiang, MD, Feilong Wang, MD, Yajuan Wang, MD, PhD, Anton Gisterå, MD, PhD, Joy Roy, MD, PhD, Gabrielle Paulsson-Berne, PhD, Ulf Hedin, MD, PhD, Amir Lerman, MD, Göran K. Hansson, MD, PhD, Joerg Herrmann, MD, Zhong-qun Yan, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 304-317 (2019)
Summary: CANTOS (Canakinumab Antiinflammatory Thrombosis Outcome Study) confirmed interleukin (IL)–1β as an appealing therapeutic target for human atherosclerosis and related complications. However, there are serious gaps in our understanding of I
Externí odkaz:
https://doaj.org/article/e107db902af34c3ba0061ffd5bde4abd
Autor:
Suzanne M. Eken, MD, PhD, Tinna Christersdottir, MD, Greg Winski, MD, Traimate Sangsuwan, MSc, Hong Jin, MD, PhD, Ekaterina Chernogubova, PhD, John Pirault, PhD, Changyan Sun, MSc, Nancy Simon, MSc, Hanna Winter, MSc, Alexandra Backlund, PhD, Siamak Haghdoost, PhD, Göran K. Hansson, MD, PhD, Martin Halle, MD, PhD, Lars Maegdefessel, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 72-82 (2019)
Summary: As a consequence of the success of present-day cancer treatment, radiotherapy-induced vascular disease is emerging. This disease is caused by chronic inflammatory activation and is likely orchestrated in part by microRNAs. In irradiated vers
Externí odkaz:
https://doaj.org/article/926ad42a8f694ea9b449c65f2a1f0718
Autor:
Maria J. Forteza, Konstantinos A. Polyzos, Roland Baumgartner, Bianca E. Suur, Marion Mussbacher, Daniel K. Johansson, Andreas Hermansson, Göran K. Hansson, Daniel F. J. Ketelhuth
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T-cell activation is characteristic during the development of atherosclerosis. While overall T-cell responses have been implicated in disease acceleration, regulatory T cells (Tregs) exhibit atheroprotective effects. The expression of the enzyme indo
Externí odkaz:
https://doaj.org/article/8ea87542973648e4934b564803e98872
Autor:
Geena Paramel Varghese, Lasse Folkersen, Rona J. Strawbridge, Bente Halvorsen, Arne Yndestad, Trine Ranheim, Kirsten Krohg‐Sørensen, Mona Skjelland, Terje Espevik, Pål Aukrust, Mariette Lengquist, Ulf Hedin, Jan‐Håkan Jansson, Karin Fransén, Göran K. Hansson, Per Eriksson, Allan Sirsjö
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 5 (2016)
BackgroundThe NLR family, pyrin domain containing 3 (NLRP3) inflammasome is an interleukin (IL)‐1β and IL‐18 cytokine processing complex that is activated in inflammatory conditions. The role of the NLRP3 inflammasome in the pathogenesis of athe
Externí odkaz:
https://doaj.org/article/4060592ea2344f89a39b7d7d914e3f45
Autor:
Urszula Rykaczewska, Quanyi Zhao, Peter Saliba-Gustafsson, Mariette Lengquist, Malin Kronqvist, Otto Bergman, Zhiqiang Huang, Kent Lund, Katarina Waden, Zara Pons Vila, Kenneth Caidahl, Josefin Skogsberg, Vladana Vukojevic, Jan H.N. Lindeman, Joy Roy, Göran K. Hansson, Eckardt Treuter, Nicholas J. Leeper, Per Eriksson, Ewa Ehrenborg, Anton Razuvaev, Ulf Hedin, Ljubica Matic
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 42(5), 659-676. LIPPINCOTT WILLIAMS & WILKINS
Background: Understanding the processes behind carotid plaque instability is necessary to develop methods for identification of patients and lesions with stroke risk. Here, we investigated molecular signatures in human plaques stratified by echogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb5442c30ed8817975e0666df3d06a9
https://hdl.handle.net/1887/3566972
https://hdl.handle.net/1887/3566972
Autor:
Thue W. Schwartz, Ulf Hedin, Roland Baumgartner, Daniel F. J. Ketelhuth, Siv A. Hjorth, Göran K. Hansson, Ljubica Perisic Matic, Gabrielle Paulsson-Berne, K P Polyzos, Martin Berg, Maria J. Forteza
Publikováno v:
Baumgartner, R, Berg, M, Matic, L, Polyzos, K P, Forteza, M J, Hjorth, S A, Schwartz, T W, Paulson-Berne, G, Hansson, G K, Hedin, U & Ketelhuth, D F J 2021, ' Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans ', Journal of Internal Medicine, vol. 289, no. 1, pp. 53-68 . https://doi.org/10.1111/joim.13142
BACKGROUND: The metabolism of tryptophan (Trp) along the kynurenine pathway has been shown to carry strong immunoregulatory properties. Several experimental studies indicate that this pathway is a major regulator of vascular inflammation and influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a9e69bbb1f76c7a9bbfaee45b3641b
https://doi.org/10.1111/joim.13142
https://doi.org/10.1111/joim.13142
Autor:
Alessandro L. Gallina, Maria Salagianni, Gabrielle Paulsson-Berne, April S. Caravaca, Glykeria Karadimou, Göran K. Hansson, Anton Gisterå, Peder S. Olofsson, Monica Centa, Evangelos Andreakos, Stephen Malin
Publikováno v:
Journal of Internal Medicine. 288:321-334
BACKGROUND The interplay between innate and adaptive immunity is central in life-threatening clinical complications of atherosclerosis such as myocardial infarction and stroke. The specific mechanisms involved and their protective versus detrimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d1acaafcfa407380e4305c11a82ca1
https://doi.org/10.1111/joim.13085
https://doi.org/10.1111/joim.13085
Autor:
Hildur Arnardottir, Göran K. Hansson, Gabrielle Paulsson-Berne, Gonzalo Artiach, Glykeria Karadimou, Miguel Carracedo, V. Mysdotter, April S. Caravaca, Sven-Christian Pawelzik, Roland Baumgartner, Silke Thul, Peder S. Olofsson, Daniel F. J. Ketelhuth, Magnus Bäck, Laura Tarnawski
Publikováno v:
Arnardottir, H, Thul, S, Karadimou, G, Pawelzik, S-C, Artiach, G, Mysdotter, V, Carracedo, M, Tarnawski, L, Caravaca, A S, Baumgartner, R, Ketelhuth, D F, Olofsson, P S, Paulsson-Berne, G, Hansson, G K & Back, M 2021, ' The resolvin D1 receptor GPR32 transduces inflammation-resolution and atheroprotection ', Atherosclerosis, vol. 331, pp. E9 . https://doi.org/10.1016/j.atherosclerosis.2021.06.032
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b77ba7bfce861f3863fc11099b9f9f0
https://portal.findresearcher.sdu.dk/da/publications/f9e60f1c-522b-4984-991c-5006a38fe395
https://portal.findresearcher.sdu.dk/da/publications/f9e60f1c-522b-4984-991c-5006a38fe395
Autor:
Peter Libby, Göran K. Hansson
Publikováno v:
Journal of the American College of Cardiology. 74:1594-1607
Concepts of atherogenesis have evolved considerably with time. Early animal experiments showed that a cholesterol-rich diet could induce fatty lesion formation in arteries. The elucidation of lipoprotein metabolism ultimately led to demonstrating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e1374b9bf440e36bfa18fff3bd5390
https://doi.org/10.1016/j.jacc.2019.07.061
https://doi.org/10.1016/j.jacc.2019.07.061