Exploring the reasons for the large density of triplex-forming oligonucleotide target sequences in the human regulatory regions

Autor: Dopazo Joaquin, Vaquerizas Juan, Goñi Josep, Orozco Modesto

Publikováno v: BMC Genomics, Vol 7, Iss 1, p 63 (2006)

Abstract Background DNA duplex sequences that can be targets for triplex formation are highly over-represented in the human genome, especially in regulatory regions. Results Here we studied using bioinformatics tools several properties of triplex tar

Externí odkaz: https://doaj.org/article/3580f54c5feb4e48b6cfaed2bb8bcb97

Exploring the reasons for the large density of triplex-forming oligonucleotide target sequences in the human regulatory regions.

Autor: Goñi JR; Molecular Modeling and Bioinformatics Unit, Institut de Recerca Biomèdica, Parc Científic de Barcelona, Josep Samitier 1-5, Barcelona 08028, Spain. rgoni@mmb.pcb.ub.es, Vaquerizas JM, Dopazo J, Orozco M

Publikováno v: BMC genomics [BMC Genomics] 2006 Mar 27; Vol. 7, pp. 63. Date of Electronic Publication: 2006 Mar 27.