Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Go, Ka Diam"'
Autor:
Wirjanata, Grennady, Lin, Jianqing, Dziekan, Jerzy Michal, El Sahili, Abbas, Chung, Zara, Tjia, Seth, Binte Zulkifli, Nur Elyza, Boentoro, Josephine, Tham, Roy, Jia, Lai Si, Go, Ka Diam, Yu, Han, Partridge, Anthony, Olsen, David, Prabhu, Nayana, Sobota, Radoslaw M., Nordlund, Pär, Lescar, Julien, Bozdech, Zbynek
Publikováno v:
In Cell Chemical Biology 18 April 2024 31(4):743-759
Autor:
Tan, Chris Soon Heng, Go, Ka Diam, Bisteau, Xavier, Dai, Lingyun, Yong, Chern Han, Prabhu, Nayana, Ozturk, Mert Burak, Lim, Yan Ting, Sreekumar, Lekshmy, Lengqvist, Johan, Tergaonkar, Vinay, Kaldis, Philipp, Sobota, Radoslaw M., Nordlund, Pär
Publikováno v:
Science, 2018 Mar 01. 359(6380), 1170-1177.
Externí odkaz:
https://www.jstor.org/stable/26401649
Autor:
Mayumi Kitagawa, Pei-Ju Liao, Kyung Hee Lee, Jasmine Wong, See Cheng Shang, Noriaki Minami, Oltea Sampetrean, Hideyuki Saya, Dai Lingyun, Nayana Prabhu, Go Ka Diam, Radoslaw Sobota, Andreas Larsson, Pär Nordlund, Frank McCormick, Sujoy Ghosh, David M. Epstein, Brian W. Dymock, Sang Hyun Lee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The Ras/Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways are essential for cancer cell survival. Here, the authors describes a molecule a131 with dual-inhibitory properties, which targets PI5P4K and mitosis, and it is involved in Ras/Raf/MEK/ERK and
Externí odkaz:
https://doaj.org/article/6b5dccbe0c124c53b9c0ce7603c0b8e2
Despite their widespread use, our understanding of how malaria drugs work remains limited. This includes chloroquine (CQ), the most successful antimalarial ever deployed. Here, we used MS-CETSA and dose-response transcriptional profiling to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eba112eb986a76441827f9defbd751b0
https://doi.org/10.21203/rs.3.rs-1301179/v1
https://doi.org/10.21203/rs.3.rs-1301179/v1
Autor:
Radoslaw M. Sobota, Pei-Ju Liao, Frank McCormick, Mayumi Kitagawa, Noriaki Minami, Nayana Prabhu, Brian W. Dymock, Sang Hyun Lee, Oltea Sampetrean, Go Ka Diam, David M. Epstein, Kyunghee Lee, Dai Lingyun, Jasmine Wong, Pär Nordlund, Sujoy Ghosh, Hideyuki Saya, Andreas Larsson, See Cheng Shang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature communications, vol 8, iss 1
Nature Communications
Nature communications, vol 8, iss 1
Achieving robust cancer-specific lethality is the ultimate clinical goal. Here, we identify a compound with dual-inhibitory properties, named a131, that selectively kills cancer cells, while protecting normal cells. Through an unbiased CETSA screen,
Akademický článek
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Akademický článek
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Autor:
Xavier Bisteau, Nayana Prabhu, Radoslaw M. Sobota, Pär Nordlund, Johan Lengqvist, Vinay Tergaonkar, Lingyun Dai, Yan Ting Lim, Lekshmy Sreekumar, Chern Han Yong, Philipp Kaldis, Chris Soon Heng Tan, Ka Diam Go, Mert Burak Ozturk
Publikováno v:
Science, 359 (6380
Proteins differentially interact with each other across cellular states and conditions, but an efficient proteome-wide strategy to monitor them is lacking. We report the application of thermal proximity coaggregation (TPCA) for high-throughput intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286bb3fc6116b23f68d95095bfde77d8
http://hdl.handle.net/10220/48481
http://hdl.handle.net/10220/48481