Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Gnoth, Kathrin"'
Autor:
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Demuth, Hans-Ulrich, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Background: Amyloid β (Aβ)-directed immunotherapy has shown promising results in preclinical and early clinical Alzheimer’s disease (AD) trials, but successful translation to late clinics has failed so far. Compelling evidence suggests that post-
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A93866
https://ul.qucosa.de/api/qucosa%3A93866/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A93866/attachment/ATT-0/
Autor:
Gnoth, Kathrin1 (AUTHOR) kathrin.gnoth@hs-anhalt.de, Bär, Joachim Wolfgang2 (AUTHOR), Rosche, Fred3 (AUTHOR), Rahfeld, Jens-Ulrich3 (AUTHOR), Demuth, Hans-Ulrich1 (AUTHOR)
Publikováno v:
PLoS ONE. 4/16/2024, Vol. 19 Issue 4, p1-16. 16p.
Autor:
Gnoth, Kathrin1 (AUTHOR) kathrin.gnoth@izi.fraunhofer.de, Geissler, Stefanie1 (AUTHOR) julia.feldhaus.99@hotmail.de, Feldhaus, Julia1 (AUTHOR) nadine.taudte@periotrap.com, Taudte, Nadine1,2 (AUTHOR) victoria.ilse@izi.fraunhofer.de, Ilse, Victoria1 (AUTHOR) jens-ulrich.rahfeld@izi.fraunhofer.de, Zürner, Sebastian3 (AUTHOR) sebastian.zuerner@izi.fraunhofer.de, Greiser, Sebastian3 (AUTHOR) sebastian.greiser@izi.fraunhofer.de, Braumann, Ulf-Dietrich3 (AUTHOR) ulf-dietrich.braumann@izi.fraunhofer.de, Rahfeld, Jens-Ulrich1 (AUTHOR) stephan.schilling@hs-anhalt.de, Cynis, Holger1 (AUTHOR) kathrin.gnoth@izi.fraunhofer.de, Schilling, Stephan1,4 (AUTHOR)
Publikováno v:
Biomolecules (2218-273X). Mar2022, Vol. 12 Issue 3, p399. 16p.
Akademický článek
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Autor:
Li, Xiaohang, Ospitalieri, Simona, Robberechts, Tessa, Hofmann, Linda, Schmid, Christina, Upadhaya, Ajeet Rijal, Koper, Marta J, Arnim, Christine A F von, Kumar, Sathish, Willem, Michael, Gnoth, Kathrin, Ramakers, Meine, Schymkowitz, Joost, Rousseau, Frederic, Walter, Jochen, Ronisz, Alicja, Balakrishnan, Karthikeyan, Thal, Dietmar Rudolf, Rijal Upadhaya, Ajeet, von Arnim, Christine A F
Publikováno v:
Brain: A Journal of Neurology; Oct2022, Vol. 145 Issue 10, p3558-3570, 13p
Autor:
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Hans-Ulrich Demuth, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Additional file 6. isoD7-Aβ formation in APP_D678N transfected HEK293 cells. HEK293 cells were transfected with wild type APP (APP_WT) and the Tottori variant APP_D678N. Samples were taken 4 and 5 days after transfection and analyzed by isoD7-Aβ an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2700cf076eed52c389d20080a6c15f65
Autor:
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Hans-Ulrich Demuth, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Additional file 7. Quantification of total Aβ and isoD7-Aβ peptides in T-Per fractions of 5xFAD mice brain treated with K11_IgG2a and isotype control. Three months old 5xFAD mice were treated intraperitoneally once a week with 500 μg, 150 μg K11_
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b69c728783c883e8e0f996957489837
Autor:
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Hans-Ulrich Demuth, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Additional file 11. Aβ(X-42) ELISA of plasma samples from 5xFAD animals treated weekly for 38 weeks with 12 mg/kg K11_IgG2a, 3D6_IgG2a and isotype control. Three-month-old 5xFAD mice were treated intraperitoneally once a week with 12 mg/kg K11_IgG2a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1401d72a975f0aff58ad447f2f8ca0
Autor:
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Hans-Ulrich Demuth, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Additional file 5. Determination of isoD7-Aβ percentage in Aβ fibrils of different ages. Aβ (1–40) and Aβ (1–42) fibrils were incubated for 1 year at 37 °C. Samples were taken at different time points, monomerized by formic acid treatment an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129703ed134faaf52cd83e2df1eb149f
Autor:
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Hans-Ulrich Demuth, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Additional file 2. Immunohistochemical analysis of Aβ deposits in human brain samples by using different anti-isoD7-Aβ antibodies. Brain slices of gray and white matter from an AD patient were incubated with the antibodies A – from the first immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e574ae4f97122cf5104c1230617843