Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT

Autor: Coxon, Fraser P., Joachimiak, Łukasz, Najumudeen, Arafath Kaja, Breen, George, Gmach, Joanna, Oetken-Lindholm, Christina, Way, Rebecca, Dunford, James E., Abankwa, Daniel, Błażewska, Katarzyna M.

Publikováno v: In European Journal of Medicinal Chemistry 12 September 2014 84:77-89

Identification of the Privileged Position in the Imidazo[1,2-a]pyridine Ring of Phosphonocarboxylates for Development of Rab Geranylgeranyl Transferase (RGGT) Inhibitors

Autor: Kaźmierczak, Aleksandra, Kusy, Damian, Niinivehmas, Sanna P., Gmach, Joanna, Joachimiak, Łukasz, Pentikäinen, Olli T., Gendaszewska-Darmach, Edyta, Błażewska, Katarzyna M.

Publikováno v: Journal of Medicinal Chemistry; 20240101, Issue: Preprints

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Identification of the Privileged Position in the Imidazo[1,2-a]pyridine Ring of Phosphonocarboxylates for Development of Rab Geranylgeranyl Transferase (RGGT) Inhibitors.

Autor: Kaźmierczak A; Institute of Technical Biochemistry, Faculty of Biotechnology and Food Sciences, Lodz University of Technology , Stefanowskiego Street 4/10, 90-924 Łódź, Poland., Kusy D; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology , Żeromskiego Street 116, 90-924 Łódź, Poland., Niinivehmas SP; Department of Biological and Environmental Science & Nanoscience Center, University of Jyväskylä , P.O. Box 35, FI-40014 University of Jyväskylä, Finland., Gmach J; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology , Żeromskiego Street 116, 90-924 Łódź, Poland., Joachimiak Ł; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology , Żeromskiego Street 116, 90-924 Łódź, Poland., Pentikäinen OT; Department of Biological and Environmental Science & Nanoscience Center, University of Jyväskylä , P.O. Box 35, FI-40014 University of Jyväskylä, Finland.; Institute of Biomedicine, University of Turku , FI-20520 Turku, Finland., Gendaszewska-Darmach E; Institute of Technical Biochemistry, Faculty of Biotechnology and Food Sciences, Lodz University of Technology , Stefanowskiego Street 4/10, 90-924 Łódź, Poland., Błażewska KM; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology , Żeromskiego Street 116, 90-924 Łódź, Poland.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2017 Nov 09; Vol. 60 (21), pp. 8781-8800. Date of Electronic Publication: 2017 Oct 17.