Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Glynn A. Morrish"'
Autor:
T. K. Ponnuswamy, Bruce Green, Sarah McLeay, S. Ramalingam, Glynn A. Morrish, L. Venkatakrishnan, M. Ramanathan, B. Devanand
Publikováno v:
The Open Obesity Journal. 6:16-24
The aim of this study was to assess and compare fat content within the liver for normal (body mass index (BMI) < 25 kg/m2), overweight (25-30 kg/m2) and obese (≥ 30 kg/m2) subjects using a noninvasive, non-contrast computed tomography (CT) quantifi
Autor:
Glynn A. Morrish, Gerd Faetkenheuer, Bruce Green, Markus Bickel, Michael Kurowski, Yvon van Delft, Thomas N. Kakuda, Andrew Hill, Giovanni Di Perri
Publikováno v:
HIV Clinical Trials. 14:92-98
Etravirine is currently approved for HIV treatment-experienced patients at a dose of 200 mg twice daily. The long terminal elimination half-life of etravirine should support once-daily dosing.In the double-blind 48-week SENSE trial, 157 antiretrovira
Publikováno v:
Clinical Pharmacokinetics. 51:319-330
A variety of body size covariates have been used in population pharmacokinetic analyses to describe variability in drug clearance (CL), such as total body weight (TBW), body surface area (BSA), lean body weight (LBW) and allometric TBW. There is cont
Publikováno v:
Addictive Disorders & Their Treatment. 3:122-128
Publikováno v:
Expert opinion on drug metabolismtoxicology. 7(6)
The prevalence of obesity and associated co-morbid conditions is increasing globally. Physiological changes accompanying obesity are likely to result in altered drug pharmacokinetics; however, there is paucity of information on how to best dose adjus
Publikováno v:
Pharmaceutical research. 26(7)
To develop a predictive pharmacokinetic model for propofol that could inform development of a dosing strategy for the obese population. A prior model that included a nonlinear relationship between clearance (CL) and Total Body Weight (TBW) was re-par
AIMS: To determine the in vitro kinetics of morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G) formation and the inhibition potential by methadone enantiomers and structurally related opioids. METHODS: M3G and M6G formation kinetics from m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feeb93d2b8c73b90ca8fdfffafd2b566
https://hdl.handle.net/1959.8/121933
https://hdl.handle.net/1959.8/121933