An N-glycan on the C2 domain of JAGGED1 is important for Notch activation

Autor: Yao Meng, Sami Sanlidag, Sacha A. Jensen, Sean A. Burnap, Weston B. Struwe, Andreas H. Larsen, Xinyi Feng, Shruti Mittal, Mark S. P. Sansom, Cecilia Sahlgren, Penny A. Handford

Publikováno v: Science Signaling, 15(755):eabo3507. American Association for the Advancement of Science (AAAS)
Meng, Y, Sanlidag, S, Jensen, S A, Burnap, S A, Struwe, W B, Larsen, A H, Feng, X, Mittal, S, Sansom, M S P, Sahlgren, C & Handford, P A 2022, ' An N-glycan on the C2 domain of JAGGED1 is important for Notch activation ', Science Signaling, vol. 15, no. 755, eabo3507 . https://doi.org/10.1126/scisignal.abo3507

The canonical members of the Jagged/Serrate and Delta families of transmembrane ligands have an extracellular, amino-terminal C2 domain that binds to phospholipids and is required for optimal activation of the Notch receptor. Somatic mutations that c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4c9efe42b092cdfc89289531844635
http://www.scopus.com/inward/record.url?scp=85139651605&partnerID=8YFLogxK

Human placental ATP diphosphohydrolase is a highly N-glycosylated plasma membrane enzyme

Autor: Orestes Tsolas, Savvas Christoforidis, Thomais Papamarcaki

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1282:257-262

Human placental ATP diphosphohydrolase (ATP-DPH), has been previously characterized as an azide-sensitive, Ca(2+)- or Mg(2+)-dependent triphospho- and diphosphonucleosidase which migrates as an 82 kDa protein band on SDS-PAGE (Christoforidis, S. et a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94670a2c0a5fb3fce179f9d08a98d45
https://doi.org/10.1016/0005-2736(96)00065-x

Evaluation of the ability of Bifidobacterium longum to metabolize human intestinal mucus

Autor: Ruiz, Lorena, Gueimonde, Miguel, Couté, Yohann, Salminen, Seppo, Sanchez, Jean-Charles, de los Reyes-Gavilán, Clara G., Margolles, Abelardo

Publikováno v: FEMS Microbiology Letters, Vol. 314, No 2 (2011) pp. 125-30
Digital.CSIC. Repositorio Institucional del CSIC
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The ability of Bifidobacterium longum to use intestinal mucus as a metabolizable source was characterized. Bifidobacterium longum biotype longum NCIMB8809 was grown in a chemically semi-defined medium supplemented with human intestinal mucus, and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::40559eddbec442d63abceebe58bc87d9
https://pubmed.ncbi.nlm.nih.gov/21105908

A specific endoplasmic reticulum export signal drives transport of stem cell factor (Kitl) to the cell surface

Autor: Beat A. Imhof, Frédérique Paulhe, Bernhard Wehrle-Haller

Publikováno v: Journal of Biological Chemistry, Vol. 279, No 53 (2004) pp. 55545-55555

Stem cell factor, also known as Kit ligand (Kitl), belongs to the family of dimeric transmembrane growth factors. Efficient cell surface presentation of Kitl is essential for the migration, proliferation, and survival of melanocytes, germ cells, hemo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb0475de23993d30d335e2237176ac9
https://archive-ouverte.unige.ch/unige:11507

Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics

Autor: Michelangelo Foti, Anjon Audhya, Scott D. Emr

Publikováno v: Molecular Biology of the Cell, Vol. 11, No 8 (2000) pp. 2673-2689

The yeast Saccharomyces cerevisiae possesses two genes that encode phosphatidylinositol (PtdIns) 4-kinases,STT4 and PIK1. Both gene products phosphorylate PtdIns at the D-4 position of the inositol ring to generate PtdIns(4)P, which plays an essentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e4a86f9b76cb4bd48afb8ecb996c4a
https://pubmed.ncbi.nlm.nih.gov/10930462