Zobrazeno 1 - 10
of 7 013
pro vyhledávání: '"Glycine receptor"'
Publikováno v:
Neural Development, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Gephyrin is thought to play a critical role in clustering glycine receptors at synapses within the central nervous system (CNS). The main in vivo evidence for this comes from Gephyrin (Gphn)-null mice, where glycine receptors are depleted fr
Externí odkaz:
https://doaj.org/article/813713a6764845f1b744b58eaaf6d624
Autor:
Fangzhi (Frank) Jia, Mohammad Ruhul Amin, Gi Tae Kwon, Amir Mousapasandi, Pei Dai, Jed Kitson, Adrian Selim, Jerome Ip
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare but debilitating disease within the stiff person syndrome (SPS) spectrum characterised by muscle rigidity, spasms, myoclonus, dysautonomia, and brainstem dysfunction. The exac
Externí odkaz:
https://doaj.org/article/c53723a201864a40ac947c98cc06ffac
Autor:
Casey I. Gallagher, David P. Bishop, Thomas E. Lockwood, Tristan Rawling, Robert J. Vandenberg
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Zinc is a ubiquitous contaminant in many buffers, purified products and common labware that has previously been suggested to impact on the results of functional GlyR studies and may inadvertently cause the effectiveness of some GlyR modulators to be
Externí odkaz:
https://doaj.org/article/4d425daf67854576a2c4286ff073812a
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Even though long-term immunosuppressant drugs (ISD) are employed to inhibit immune system activity, enhancing graft functionality and patient survival in solid organ transplantation (SOT), these transplants often lead to immune complications, with po
Externí odkaz:
https://doaj.org/article/835d0f0907114ac79c39c9ca87b82ca9
Akademický článek
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Autor:
Mohamed Darwish, Satoko Hattori, Hirofumi Nishizono, Tsuyoshi Miyakawa, Nozomu Yachie, Keizo Takao
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Glycine receptors (GlyRs) are ligand-gated chloride channels comprising alpha (α1–4) and β subunits. The GlyR subunits play major roles in the mammalian central nervous system, ranging from regulating simple sensory information to modula
Externí odkaz:
https://doaj.org/article/67975a345ce741dcad595056f6cd61e1
Autor:
Bruna de Freitas Dias, Fabio Fieni Toso, Maria Eduarda Slhessarenko Fraife Barreto, René de Araújo Gleizer, Alessandra Dellavance, Pedro André Kowacs, Helio Teive, Mariana Spitz, Aline Freire Borges Juliano, Letícia Januzi de Almeida Rocha, Pedro Braga-Neto, Paulo Ribeiro Nóbrega, Jamary Oliveira-Filho, Ronaldo Maciel Dias, Clécio de Oliveira Godeiro Júnior, Fernanda Martins Maia, Rodrigo Barbosa Thomaz, Mara Lúcia Santos, Eduardo Sousa de Melo, Adaucto Wanderley da Nóbrega Júnior, Katia Lin, Orlando Graziani Povoas Barsottini, Verena Endmayr, Luís Eduardo Coelho Andrade, Romana Höftberger, Lívia Almeida Dutra
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe frequency of antibodies in autoimmune encephalitis (AIE) may vary in different populations, however, data from developing countries are lacking. To describe the clinical profile of AIE in Brazil, and to evaluate seasonality and predicto
Externí odkaz:
https://doaj.org/article/1ec1a066d9ce40ae8476221f4af89472
Autor:
Alexey V. Rossokhin
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 16, Iss 4, Pp 44-53 (2022)
Anion-conducting cys-loop receptors activated by -aminobutyric acid (GABAАRs) and glycine (GlyRs) have inhibitory activity in the brain and spinal cord. GABAАRs and GlyRs are targets for various substances that potentiate or inhibit the receptor fu
Externí odkaz:
https://doaj.org/article/2c37a8e0dd2b472d8339853927c68d23
Akademický článek
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Autor:
Steffen Fricke, Magnus Harnau, Florian Hetsch, Haoran Liu, Julia Leonhard, Anna Eylmann, Pina Knauff, Han Sun, Marcus Semtner, Jochen C. Meier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The monovalent cations sodium and potassium are crucial for the proper functioning of excitable cells, but, in addition, other monovalent alkali metal ions such as cesium and lithium can also affect neuronal physiology. For instance, there have been
Externí odkaz:
https://doaj.org/article/c6e55ab9c8504a9b94c27eea153f2d6d