Výsledky vyhledávání - "Glutathione transferase T1"

Glutathione S-Transferase M1 and T1 Gene Polymorphisms in Patients with Chronic Plaque-Type Psoriasis: A Case-Control Study

Autor: Mutlu Karkucak, Esma Uslu, Teoman Erdem, Hakan Turan, Sebnem Ozemri Sag, Tahsin Yakut, Gokhan Ocakoglu, Berna Solak

Publikováno v: Medical Principles and Practice

Objective: To determine the role of glutathione S-transferase (GST) isoenzyme polymorphisms as susceptibility factors in patients with psoriasis in a Turkish cohort. Subjects and Methods: In this case-control study, 105 patients with plaque-type psor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bf211514e960d76bd3f0cc9a66b068
https://doi.org/10.1159/000442165

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Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics

Autor: Alice Matimba, Adebowale Adeyemo, Himla Soodyall, Giuseppe Novelli, Kelli K. Ryckman, Charles N. Rotimi, Renato Mariani-Costantini, Raj Ramesar, Giorgio Sirugo, Branwen J. Hennig, Scott M. Williams, Muntaser E. Ibrahim, Alessandra Tacconelli, Melanie J. Newport, Sarah A. Tishkoff

Publikováno v: Human Genetics. 123:557-598

Africa is the ultimate source of modern humans and as such harbors more genetic variation than any other continent. For this reason, studies of the patterns of genetic variation in African populations are crucial to understanding how genes affect phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8a30bb24c5bf4e5168bf5fc7b776d8
https://doi.org/10.1007/s00439-008-0511-y

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Modulatory role of GSTM1 null genotype on the frequency of micronuclei in pesticide-exposed agricultural workers

Autor: Alaattin Sen, Seda Savranoglu, Gulsum Terzioglu, Pelin Atmaca, Tugba Boyunegmez Tumer, Sevki Arslan

Publikováno v: Toxicology and industrial health. 32(12)

In this study, we aimed to investigate the extent of genotoxic risk and the association between null GSTM1/GSTT1 and GSTP1 Ile105Val variants and cellular DNA damage, as measured by micronucleus (MN) assay in a group of agricultural workers from Deni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0a65beae8e4196bf117637a2d9f7b0
https://pubmed.ncbi.nlm.nih.gov/26381689

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Cigarette Smoking and Colorectal Cancer: APC Mutations, hMLH1 Expression, and GSTM1 and GSTT1 Polymorphisms

Autor: Pieter van 't Veer, Piet A. van den Brandt, Goos N.P. van Muijen, Ellen Kampman, Margreet Lüchtenborg, Matty P. Weijenberg, Anton F.P.M. de Goeij, Maurice P. Zeegers, R. Alexandra Goldbohm, Guido M.J.M. Roemen

Publikováno v: American Journal of Epidemiology, 161, 806-15
American Journal of Epidemiology, 161(9), 806-815
American Journal of Epidemiology, 161, 9, pp. 806-15
American Journal of Epidemiology 161 (2005) 9
American Journal of Epidemiology, 161(9), 806-815. Oxford University Press
American Journal of Epidemiology, 9, 161, 806-815

The contribution of cigarette smoking to sporadic colorectal cancer may differ according to molecular aspects of the tumor or according to glutathione S-transferase M1 (GSTM1) or glutathione S-transferase T1 (GSTT1) genotype. In the prospective Nethe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e690dc5a8bfd2f3f2934a0faefda55
https://doi.org/10.1093/aje/kwi114

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Associations analysis of GSTM1, T1 and P1 Ile105Val polymorphisms with carpal tunnel syndrome

Autor: Ozlem Gorukmez, Esra Erkol İnal, Ali Topak, Pınar Eroğlu, Tahsin Yakut, Sebnem Ozemri Sag

Publikováno v: Clinical rheumatology. 35(5)

Oxidative stress was related with carpal tunnel syndrome (CTS). We aimed to clarify the associations between glutathione S-transferase (GST)M1, GSTT1 and GSTP1-Ile105Val polymorphisms and CTS. One hundred-forty patients with CTS and 97 healthy contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e3d242c8bbd6bcc15d8e09952fd789
https://pubmed.ncbi.nlm.nih.gov/25566970

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Polymorphisms of glutathione-s-transferase M1, T1, and P1 genes in endometrial carcinoma

Autor: Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Bölümü., Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genetik Anabilim Dalı., Özerkan, Kemal, Atalay, Mehmet Aral, Yakut, Tahsin, Doster, Y., Yılmaz, Emel, Karkucak, Mutlu, AAH-9791-2021, ABI-5648-2022

Objective: To investigate the polymorphism rates and possible roles of glutathione-s-transferase M1, T1, and P1 gene polymotphisms in the predisposition to endometrial cancer in Caucasian women. Materials and Methods: Serum samples and medical record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______9458::f239371abc5991fb83590c051476dea7
http://hdl.handle.net/11452/33098

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GST (GSTM1, GSTT1, and GSTP1) polymorphisms in the genetic susceptibility of Turkish patients to cervical cancer

Autor: Kemal Özerkan, Beray Kiran, Mutlu Karkucak, Tahsin Yakut, Sebnem Ozemri Sag, Hakan Ozan, Mehmet Ture

Objective: This work investigates the role of glutathione S-transferase M1 (GSTM1), glutathione S-transferase T1 (GSTT1), and glutathione S-transferase P1 (GSTP1) enzymes and polymorphisms, which are found in phase II detoxification reactions in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d35c88bed61903308ee2afe56052ae
http://hdl.handle.net/11452/23126

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Lack of association of genetic polymorphisms of angiotensin-converting enzyme gene i/d and glutathione-s-transferase enzyme t1 and m1 with retinopathy of prematures

Autor: Tahsin Yakut, Ozmen A, M Karkucak, Meral Yildiz, O. Gorukmez

One of the most frequently observed causes of blindness in infancy is the pathogenesis known as retinopathy of prematurity (ROP). Angiotensin-converting enzyme (ACE) is a vital enzyme in the renin-angiotensin-aldosterone system; it is involved in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1449f851ca58d45ccdc937f5dec462
http://hdl.handle.net/11452/25317

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Effects of azithromycin on glutathione S-transferases in cystic fibrosis airway cells

Autor: Gabriella Bergamini, Paola Melotti, Alfonso Pompella, Baroukh M. Assael, Marco Della Peruta, Francxois A. Huaux, Cristina Cigana, Alessandro Corti, Claudio Sorio, Teresinha Leal

Publikováno v: American journal of respiratory cell and molecular biology. 41(2)

Anti-inflammatory properties of azithromycin (AZM) have been proposed as possible mechanisms of clinical beneficial effects in patients with cystic fibrosis (CF). Altered glutathione (GSH) transport in cystic fibrosis transmembrane regulator protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb5a2ac971c2a807f6684141d5517fa
https://pubmed.ncbi.nlm.nih.gov/19097986

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Effect of urban traffic, individual habits, and genetic polymorphisms on background urinary 1-hydroxypyrene excretion

Autor: Pierluigi Cocco, Maria Monne, Antonio Ibba, Silvia Mattuzzi, Giannina Satta, C Flore, Maria Giuseppina Tocco, Patrick S. Moore, M. G. Ennas, Mariagrazia Zucca, Stefania Collu, Aldo Scarpa, Giovanna Piras, M Meloni

Biomarkers of individual susceptibility: field studiesBiomarker (including alleles if genetic): (Ex7C295C/T) in (CYP1A2) gene, GSTT1, GSTM1Effect studied (phenotype/pathology): PAH metabolismMethod of analysis: HPLC, PCRStudy design: case-controlStud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9ada836d1f75be54ba22ac75145965

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