Zobrazeno 1 - 10 of 22 208 pro vyhledávání: '"Glutamate-cysteine ligase"'
1
Akademický článek
Novel Inhibitor of Glutamate-Cysteine Ligase Catalytic Subunit against Tribolium castaneum : High-Throughout Virtual Screening, Molecular Docking and Dynamics Simulation, and Bioassay.
Autor: Kim K; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210046, China.; Department of Life-Science, University of Science, Pyongyang 999093, Democratic People's Republic of Korea., Chen P; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210046, China., Li C; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210046, China., Li B; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210046, China.
Publikováno v: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Aug 14; Vol. 72 (32), pp. 17813-17823. Date of Electronic Publication: 2024 Jul 30.
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2
Akademický článek
Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern.
Autor: Xue Z; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China., Nuerrula Y; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China., Sitiwaerdi Y; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China., Eli M; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Publikováno v: Biomolecules & biomedicine [Biomol Biomed] 2024 May 02; Vol. 24 (3), pp. 545-559. Date of Electronic Publication: 2024 May 02.
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3
Akademický článek
Inhibition of the glutamate-cysteine ligase catalytic subunit with buthionine sulfoximine enhances the cytotoxic effect of doxorubicin and cyclophosphamide in Burkitt lymphoma cells.
Autor: Kazimierska M; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland.; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland., Leśniewska A; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland., Bakker A; Department of Pathology & Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Diepstra A; Department of Pathology & Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Kasprzyk ME; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland., Podralska M; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland., Rassek K; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland., Kluiver J; Department of Pathology & Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., van den Berg A; Department of Pathology & Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Rozwadowska N; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland., Dzikiewicz-Krawczyk A; Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland. agnieszka.dzikiewicz-krawczyk@igcz.poznan.pl.
Publikováno v: Journal of applied genetics [J Appl Genet] 2024 Feb; Vol. 65 (1), pp. 95-101. Date of Electronic Publication: 2023 Nov 02.
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4
Akademický článek
Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis.
Autor: Zhang LH; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Innovative Genomics Institute, Berkeley, CA, 94704, USA., Tang M; Innovative Genomics Institute, Berkeley, CA, 94704, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Tao X; Innovative Genomics Institute, Berkeley, CA, 94704, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720, USA., Shao Q; Innovative Genomics Institute, Berkeley, CA, 94704, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720, USA., Thomas V; Innovative Genomics Institute, Berkeley, CA, 94704, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720, USA., Shimizu S; Drug Discovery Technology, Ono Pharmaceutical Company, Ltd., Osaka, 618-858, Japan., Kasano M; Drug Discovery Technology, Ono Pharmaceutical Company, Ltd., Osaka, 618-858, Japan., Ishikawa Y; Research Center of Oncology, Ono Pharmaceutical Company, Ltd., Osaka, 618-8585, Japan., Inukai T; Drug Discovery Chemistry, Ono Pharmaceutical Company, Ltd., Osaka, 618-858, Japan., Nomura DK; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Innovative Genomics Institute, Berkeley, CA, 94704, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, 94720, USA.
Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 Dec 01; Vol. 24 (23), pp. e202300371. Date of Electronic Publication: 2023 Oct 12.
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5
Akademický článek
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6
Akademický článek
Involvement of Glutamate Cysteine Ligase Genes in Tolerance to Emamectin Benzoate in Spodoptera frugiperda and Their Putative Regulatory Mechanisms.
Autor: Cao X; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Wei J; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Ge H; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Guan D; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Li H; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Zhang H; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Zheng Y; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Qian K; College of Plant Protection, Yangzhou University, Yangzhou 225009, China., Wang J; College of Plant Protection, Yangzhou University, Yangzhou 225009, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education, Yangzhou University, Yangzhou 225009, China.
Publikováno v: Journal of agricultural and food chemistry [J Agric Food Chem] 2023 Sep 20; Vol. 71 (37), pp. 13717-13728. Date of Electronic Publication: 2023 Sep 10.
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7
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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9
Akademický článek
Glutamate-cysteine ligase catalytic and its modifier function as novel immunotargets in gastric adenocarcinoma.
Autor: Da D; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Pan Z; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Zeng L; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Dang Y; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Dang C; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Huang Y; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Shi D; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China., Li H; Department of Oncology, Gansu Provincial Hospital, The First Clinical Medical College of Gansu University of Chinese Medicine, 204 Donggang West Road, Lanzhou, Gansu 730000, PR China. Electronic address: lihongling1969@126.com.
Publikováno v: Asian journal of surgery [Asian J Surg] 2023 Jan; Vol. 46 (1), pp. 143-149. Date of Electronic Publication: 2022 Mar 01.
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10
Akademický článek
Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern
Autor: Zhaoyuan Xue, Yiliyaer Nuerrula, Yilidana Sitiwaerdi, Mayinur Eli
Publikováno v: Biomolecules & Biomedicine (2024)
The enzyme glutamate-cysteine ligase modifier subunit (GCLM) serves as the initial rate-limiting factor in glutathione (GSH) synthesis. GSH is the preferred substrate for glutathione peroxidase 4 (GPX4), directly impacting its activity and stability.
Externí odkaz: https://doaj.org/article/034685b021ed4397a7ac18a565c8564d
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