Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo

Autor: Denis Duboule, Jozsef Zakany

Publikováno v: BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)
BMC Research Notes, Vol. 11, No 1 (2018) P. 193
BMC Research Notes

We had previously reported [1] a mouse line carrying the Atypical female courtship (HoxDAfc) allele, where an ectopic accumulation of Hoxd10 transcripts was observed in a sparse population of cells in the adult isocortex, as a result of a partial del

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6cffa730cd862cc7f45eff535d6e7c
http://link.springer.com/article/10.1186/s13104-018-3307-8

New pool of cortical interneuron precursors in the early postnatal dorsal white matter

Autor: Cécile Lebrand, Jozsef Zoltan Kiss, O Riccio, Sahana Murthy, Alexandre Dayer, Gábor Szabó, Laszlo Vutskits, Tania Vitalis

Publikováno v: Cerebral cortex (New York N.Y. : 1991)
Cerebral Cortex
Cerebral Cortex, vol. 22, no. 1, pp. 86-98
Cerebral Cortex, Vol. 22, No 1 (2012) pp. 86-98

The migration of cortical γ-aminobutyric acidergic interneurons has been extensively studied in rodent embryos, whereas few studies have documented their postnatal migration. Combining in vivo analysis together with time-lapse imaging on cortical sl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3ec69afe3edee46e752dc669e1ea96

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

Autor: Carla Borri Voltattorni, Itamar Kass, Nathan Cowieson, Malcolm Buckle, David Perahia, Mauricio G. S. Costa, Daniel Christ, David B. Langley, David E. Hoke, Eugenia Pennacchietti, Ian R. Mackay, Oded Kleifeld, Cyril F. Reboul, Hervé Leh, Benjamin T. Porebski, Ashley M. Buckle, Julia M. McCoey, Brendan Roome, Daniela De Biase, Alessandro Paiardini

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (25), pp.E2524-2529. ⟨10.1073/pnas.1403182111⟩

International audience; The human neuroendocrine enzyme glutamate decarboxylase (GAD) catalyses the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) using pyridoxal 5′-phosphate as a cofactor. GAD exists as two isoforms n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d16d55162420f70d6b6626fd7318824
https://hal-riip.archives-ouvertes.fr/pasteur-01146884

SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development

Autor: Denis Jabaudon, Jeffrey D. Macklis, Ryann M. Fame, Eiman Azim

Publikováno v: Nature Neuroscience, Vol. 12, No 10 (2009) pp. 1238-1247
Nature neuroscience

Summary The extraordinary neuronal diversity of the central nervous system emerges largely from controlled spatial and temporal segregation of cell type-specific molecular regulators. Here, we report that the transcription factor SOX6 controls the mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f9cb1b80aaf99c0e2814cce4cffc14
https://archive-ouverte.unige.ch/unige:19601

RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area

Autor: Masahiko Watanabe, Christian Lüscher, Marta Lomazzi, Cyril Creton, Kevin Wickman, Yuchio Yanagawa, Gwenaël Labouèbe, Stephanie B. Boyer, Meng Li, Hans G Cruz, Rafael Luján, Kunihiko Obata, Paul A. Slesinger

Publikováno v: Nature Neuroscience, Vol. 10, No 12 (2007) pp. 1559-1568

Agonists of GABA(B) receptors exert a bi-directional effect on the activity of dopamine (DA) neurons of the ventral tegmental area, which can be explained by the fact that coupling between GABA(B) receptors and G protein-gated inwardly rectifying pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7860173b7bafc0a23091a5bab65d28
https://pubmed.ncbi.nlm.nih.gov/17965710