Role of Klotho in Hyperglycemia: Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration

Autor: Dorota Rogacka, Tomasz Kulesza, Patrycja Rachubik, Irena Audzeyenka, Agnieszka Piwkowska, Stefan Angielski, Marlena Typiak, Moin A. Saleem

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7867, p 7867 (2021)
Typiak, M, Kulesza, T, Rachubik, P, Rogacka, D, Audzeyenka, I, Angielski, S, Saleem, M A & Piwkowska, A 2021, ' Role of Klotho in Hyperglycemia : Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration ', International Journal of Molecular Sciences, vol. 22, no. 15, 7867 . https://doi.org/10.3390/ijms22157867
Volume 22
Issue 15

Hyperglycemic conditions (HG), at early stages of diabetic nephropathy (DN), cause a decrease in podocyte numbers and an aberration of their function as key cells for glomerular plasma filtration. Klotho protein was shown to overcome some negative ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdb78a19e8f03e20f1e8f18c6e6e335
http://europepmc.org/articles/PMC8345972

Phosphosite charge rather than shootward localization determines OCTOPUS activity in root protophloem

Autor: Christian S. Hardtke, Alice S. Breda, Ora Hazak

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 28, pp. E5721-E5730

Polar cellular localization of proteins is often associated with their function and activity. In plants, relatively few polar-localized factors have been described. Among them, the plasma membrane-associated Arabidopsis proteins OCTOPUS (OPS) and BRE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dc89a0e68bbd3a8a263a73ded022bc
https://doi.org/10.1073/pnas.1703258114

A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development

Autor: Qian Chen, Tom Beeckman, Gert Van Isterdael, Peter Marhavý, Jiří Friml, Niko Geldner, Zidian Xie, Jessica R. Lucas, Krzysztof Wabnik, Yang Liu, EunKyoung Lee, Steffen Vanneste, Wei Xuan, Jie Le, Fred D. Sack, Eva Benková, Valya Vassileva, Chuanyou Li, Erich Grotewold, Hidehiro Fukaki, Saeko Kitakura, Steven Maere

Publikováno v: Nature Communications
NATURE COMMUNICATIONS
Nature Communications, vol. 6, pp. 8821

Multiple plant developmental processes, such as lateral root development, depend on auxin distribution patterns that are in part generated by the PIN-formed family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7 (ARF7) and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ef7464097799c48e541ee24a98b087
http://europepmc.org/articles/PMC4673502

Rapid colorimetric quantification of lipo-chitoologosaccharides from Mesorhizobium loti and Sinorhizobium meliloti

Autor: Joachim Goedhart, Jean-Jacques Bono, Theodorus W. J. Gadella

Publikováno v: Molecular Plant-Microbe Interactions, 15, 859-865. American Phytopathological Society
Molecular Plant-Microbe Interactions
Molecular Plant-Microbe Interactions, American Phytopathological Society, 2002, 15 (9), pp.859-865

Nod factors are lipids with a chitinlike headgroup produced by gram-negative Rhizobium bacteria. These lipo-chitooligosaccharides (LCOs) are essential signaling molecules for accomplishing symbiosis between the bacteria and roots of legume plants. De

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d217b680175c33747a625e6d75f52da
https://dare.uva.nl/personal/pure/en/publications/rapid-colorimetric-quantification-of-lipochitoologosaccharides-from-mesorhizobium-loti-and-sinorhizobium-meliloti(25ae5bfe-72a6-4f3c-9389-c228571d5948).html

The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes

Autor: Seifert, R., Hageluken, A., Hoer, A., Hoer, D., Sergio Grunbaum, Offermanns, S., Schwaner, I., Zingel, V., Schunack, W., Schultz, G.

Publikováno v: Scopus-Elsevier

In dibutyryl-cAMP-differentiated HL-60 cells, histamine H1 and formyl peptide receptors mediate increases in the cytosolic Ca2+ concentration ([Ca2+]i) via pertussis toxin-sensitive G proteins of the Gi family. We compared the effects of 2-(3-chlorop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03643953b7de3e2b4da1b1f26b0b193d
https://epub.uni-regensburg.de/23302/