Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Glucosides/pharmacology"'
Autor:
Olof Bengtsson, Mikhail Kosiborod, Jose C. Nicolau, Marc S. Sabatine, Kieran F. Docherty, Lars Køber, Felipe Martinez, Pardeep S. Jhund, Béla Merkely, Mirta Diez, Piotr Ponikowski, Mark C. Petrie, Daniel Lindholm, Silvio E. Inzucchi, David L. DeMets, Anna Maria Langkilde, John J.V. McMurray, Mikaela Sjöstrand, Subodh Verma, Masafumi Kitakaze, Anna Niklasson, Scott D. Solomon
Publikováno v:
Kosiborod, M N, Jhund, P S, Docherty, K F, Diez, M, Petrie, M C, Verma, S, Nicolau, J C, Merkely, B, Kitakaze, M, DeMets, D L, Inzucchi, S E, Køber, L, Martinez, F A, Ponikowski, P, Sabatine, M S, Solomon, S D, Bengtsson, O, Lindholm, D, Niklasson, A, Sjöstrand, M, Langkilde, A M & McMurray, J J V 2020, ' Effects of Dapagliflozin on Symptoms, Function, and Quality of Life in Patients With Heart Failure and Reduced Ejection Fraction : Results From the DAPA-HF Trial ', Circulation, vol. 141, no. 2, pp. 90-99 . https://doi.org/10.1161/CIRCULATIONAHA.119.044138
Background: Goals of management in patients with heart failure and reduced ejection fraction include reducing death and hospitalizations, and improving health status (symptoms, physical function, and quality of life). In the DAPA-HF trial (Dapagliflo
Autor:
Cecilia Carubbi, Elena Masselli, Riccardo R.C. Bonadonna, Giuliana Gobbi, Anna Solini, Alessandra Dei Cas, Giulia Pozzi, Valentina Spigoni, Federica Fantuzzi
Publikováno v:
Cardiovascular Diabetology
Cardiovascular diabetology, 19 (1
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-15 (2020)
Cardiovascular diabetology, 19 (1
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-15 (2020)
The clear evidence of cardiovascular benefits in cardiovascular outcome trials of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in type 2 diabetes might suggest an effect on atherosclerotic plaque vulnerability and/or thrombosis, in which myeloi
Autor:
Steven W. Wingett, Kassim Kamaka, Danika L. Hill, Martin S. Zand, Jiong Wang, Elizabeth F. Wallin, Catherine Mkindi, François Spertini, Wim Pierson, Régine Audran, Daniel J. Bolland, Said Jongo, Sophie Houard, Michelle A. Linterman, Anne E. Corcoran, Edward J. Carr, Claudia Daubenberger
Publikováno v:
The Journal of experimental medicine, vol. 216, no. 8, pp. 1857-1873
The Journal of Experimental Medicine
The Journal of Experimental Medicine
A rational strategy to achieve optimal vaccine responses is to potentiate Tfh cells and the germinal center response. This work shows the adjuvant GLA-SE enhances circulating Tfh cells and enduring antibody responses to a malaria vaccine in Tanzanian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02643e911e2eb9a88542a1b440cd038
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844
Autor:
Andrew T. Hattersley, Bernard Thorens
Publikováno v:
New England Journal of Medicine, vol. 373, no. 10, pp. 974-976
New England Journal of Medicine
New England Journal of Medicine
Dapagliflozin targets the sodium-coupled glucose transporter type 2 in the renal proximal tubule, preventing the reabsorption of glucose into the blood. It also has a direct effect on the islet alpha cell, which may counter its effect on glucose reab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e7151acd5054c3a1711d236ea76a9c
https://serval.unil.ch/resource/serval:BIB_DA645CAAB37A.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_DA645CAAB37A.P001/REF.pdf
Autor:
Richard Daniellou, Laurent Legentil, Caroline Nugier-Chauvin, Jean-Luc Audic, Vincent Ferrières
Publikováno v:
Carbohydrate Research
Carbohydrate Research, Elsevier, 2011, 346 (12), pp.1541-5. ⟨10.1016/j.carres.2011.04.025⟩
Carbohydrate Research, 2011, 346 (12), pp.1541-5. ⟨10.1016/j.carres.2011.04.025⟩
Carbohydrate Research, Elsevier, 2011, 346 (12), pp.1541-5. ⟨10.1016/j.carres.2011.04.025⟩
Carbohydrate Research, 2011, 346 (12), pp.1541-5. ⟨10.1016/j.carres.2011.04.025⟩
International audience; An improved synthesis of n-octyl β-D-galactofuranoside was described using micro-wave activation. The resulting alkyl furanoside showed antibacterial activity against Mycobacterium smegmatis, a non-pathogenic model of Mycobac
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2001, 61 (18), pp.6876--84
Scopus-Elsevier
Cancer Research, American Association for Cancer Research, 2001, 61 (18), pp.6876--84
Scopus-Elsevier
Specific phosphorylation of serine- and arginine-rich pre-mRNA splicing factors (SR proteins) is one of the key determinants regulating splicing events. Several kinases involved in SR protein phosphorylation have been identified and characterized, am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4d20dac7592a127d1ab694d06ccad65c
https://hal.archives-ouvertes.fr/hal-02197311
https://hal.archives-ouvertes.fr/hal-02197311
Publikováno v:
Brehm, K, Ripio, M T, Kreft, J & Vazquez-Boland, J A 1999, ' The bvr locus of Listeria monocytogenes mediates virulence gene repression by beta-glucosides ', Journal of Bacteriology, vol. 181, no. 16, pp. 5024-32 .
The beta-glucoside cellobiose has been reported to specifically repress the PrfA-dependent virulence genes hly and plcA in Listeria monocytogenes NCTC 7973. This led to the hypothesis that beta-glucosides, sugars of plant origin, may act as signal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::3c02a81b212ef06c863f8387ff8f29cc
https://www.pure.ed.ac.uk/ws/files/13396078/The_bvr_Locus_of_Listeria_monocytogenes.pdf
https://www.pure.ed.ac.uk/ws/files/13396078/The_bvr_Locus_of_Listeria_monocytogenes.pdf
Autor:
C. Saponaro, Julien Thevenet, Ana Acosta-Montalvo, Markus Mühlemann, Miriam Cnop, Ericka Moerman, Caroline Bonner, Bart Staels, Anais Coddeville, Julie Kerr-Conte, François Pattou, Anthony Piron, Valery Gmyr, Gianni Pasquetti, Nathalie Delalleau
Publikováno v:
Diabetes (New York, N.Y.), 69 (5
Diabetes
Diabetes
Studies implicating sodium-glucose cotransporter 2 (SGLT2) inhibitors in glucagon secretion by pancreatic α-cells reported controversial results. We hypothesized that interindividual heterogeneity in SGLT2 expression and regulation may affect glucag