Zobrazeno 1 - 10
of 2 904
pro vyhledávání: '"Glucosidase Inhibitor"'
Autor:
Prakash Shoba Savariyar Adimy, Mohamed S. Elshikh, Mohammad Ajmal Ali, Gurupatham Devadhasan Biji
Publikováno v:
BioResources, Vol 19, Iss 4, Pp 8368-8387 (2024)
Agro-residues, including banana peel, pineapple peel, mango peel, apple peel, and coconut husk, were utilized to produce extracellular polysaccharide (EPS) via solid state fermentation(SSF) by the fungus, Trichoderma hamatum. EPS production was highe
Externí odkaz:
https://doaj.org/article/4a68fc91bb9c4c9eb96bb214b05b1a51
Publikováno v:
Jurnal Kimia Sains dan Aplikasi, Vol 27, Iss 7, Pp 316-327 (2024)
Diabetes mellitus (DM) is a chronic metabolic disorder posing a significant health risk. Effective treatments are continually sought. Coumarin derivatives with oxime ester groups have shown potential as antidiabetic agents by inhibiting the α-glucos
Externí odkaz:
https://doaj.org/article/67383bdd7cc74f56aef6117283c8f3cd
Autor:
Mohammad Hossein Sayahi, Samira Zareei, Mohammad Halimi, Majid Alikhani, Ali Moazzam, Maryam Mohammadi-Khanaposhtani, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Hossein Rastegar, Parham Taslimi, Essam H. Ibrahim, Hamed A. Ghramh, Bagher Larijani, Mohammad Mahdavi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract In this work, a novel series of N-phenylacetamide-1,2,3-triazole-indole-2-carboxamide derivatives 5a–n were designed by consideration of the potent α-glucosidase inhibitors containing indole and carboxamide-1,2,3-triazole-N-phenylacetamid
Externí odkaz:
https://doaj.org/article/f521396235d74b39a4f53cbae1528860
Publikováno v:
Food Production, Processing and Nutrition, Vol 6, Iss 1, Pp 1-12 (2024)
Abstract Olive (Olea europaea) phytochemicals are associated with a reduced risk of type 2 diabetes. Table olives typically have higher phytochemical concentrations than olive oil, but their impact on human intestinal α-glucosidase is largely unknow
Externí odkaz:
https://doaj.org/article/444f9435daef49799fa773fe9eea6578
Autor:
Niels B Dalsgaard, Lærke S Gasbjerg, Laura S Hansen, Dennis S Nielsen, Torben S Rasmussen, Filip K Knop
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-7 (2024)
Aim: The alpha-glucosidase inhibitor acarbose is approved for the treatment of type 2 diabetes (T2D). It acts in the lumen of the gut by reducing intestinal hydrolysis and absorption of ingested carbohydrates. This reduces postprandial blood glucose
Externí odkaz:
https://doaj.org/article/fc39470700c2487790ef240db845be3a
Publikováno v:
F1000Research, Vol 13 (2024)
Background The prevalence of diabetes mellitus (DM) is increasing overtime, potentially leading to various severe health complications and mortality. Despite therapeutic agents have currently been developed, unexpected adverse effects are inevitable.
Externí odkaz:
https://doaj.org/article/884ffa0d6f6b417b8e68ee2a23117fb7
Publikováno v:
eFood, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Mulberry (Morus alba L.) leaf can effectively inhibit the digestion of starchy foods, and α‐glucosidase (AG) is its main target. This study employed an untargeted metabolomics approach combined with molecular docking to identify AG inhibi
Externí odkaz:
https://doaj.org/article/c4840cfc7deb4ae6b53da1f877ea5e84
Autor:
Samhita Bhaumik, Alekhya Sarkar, Sudhan Debnath, Bimal Debnath, Rajat Ghosh, Magdi E.A. Zaki, Sami A. Al-Hussain
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 6, Pp 102095- (2024)
Background: According to the International Diabetes Federation, there will be 578 million individuals worldwide with diabetes by 2030 and 700 million by 2045. One of the promising drug targets to fight diabetes is α-glucosidase (AG), and its inhibit
Externí odkaz:
https://doaj.org/article/93be90a3e55b4e219e0f5b7f3e1f1e21
Publikováno v:
Majalah Obat Tradisional, Vol 28, Iss 3, Pp 221-229 (2023)
Yacon (Smallanthus sonchifolius) is a plant that is vastly cultivated in Indonesia and has anti-diabetic activity. The purpose of this study was to isolate the compounds from the semipolar fraction of yacon leaves, as well as test them in silico and
Externí odkaz:
https://doaj.org/article/a0e931c6520443e3997cf54f3c6c6222
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8461-8475 (2023)
Natural products are a boundless source for the development of pharmaceutical agents against a wide range of human diseases. Accordingly, naturally occurring aurones possess various biological benefits, such as anticancer, antioxidant, antimicrobial,
Externí odkaz:
https://doaj.org/article/04b5a8c503534e3f852a8bef034e7ed0