Výsledky vyhledávání - "Glucose chemistry"

Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the gamma subunit

Autor: Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, Toshiaki, Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., Asano, T.

Publikováno v: J Biol Chem. 290(No. 40):24255-66

AMP-activated protein kinase (AMPK) plays a critical role in metabolic regulation. In this study, first, it was revealed that Pin1 associates with any isoform of γ, but not with either the α or the β subunit, of AMPK. The association between Pin1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c044f81abe16311541a69e4c15e74de7
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100786926

Zobrazit plný text záznamu

Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes*

Autor: Philipp Kaldis, Oksana Gavrilova, Ji Hyeon Lee, Sushil G. Rane, Matthew J. Merrins, Leslie S. Satin, So Yoon Kim, Xavier Bisteau

Publikováno v: The Journal of biological chemistry, 292 (9

The failure of pancreatic islet β-cells is a major contributor to the etiology of type 2 diabetes. β-Cell dysfunction and declining β-cell mass are two mechanisms that contribute to this failure, although it is unclear whether they are molecularly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb09d523bcfdfe746d0251f05e1368e
https://europepmc.org/articles/PMC5339765/

Zobrazit plný text záznamu

Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease:Metabolic basis for dementia

Publikováno v: Xu, J, Begley, P, Church, S J, Patassini, S, McHarg, S, Kureishy, N, Hollywood, K A, Waldvogel, H J, Liu, H, Zhang, S, Lin, W, Herholz, K, Turner, C, Synek, B J, Curtis, M A, Rivers-Auty, J, Lawrence, C B, Kellett, K A B, Hooper, N M, Vardy, E R L C, Wu, D, Unwin, R D, Faull, R L M, Cooper, G J S & Dowsey, A 2016, ' Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease : Metabolic basis for dementia ', Scientific Reports, vol. 6, 27524 . https://doi.org/10.1038/srep27524
Scientific Reports
Xu, J, Begley, P, Church, S, Patassini, S, Mcharg, S, Kureishy, N, Hollywood, K, Waldvogel, H J, Liu, H, Zhang, S, Lin, W, Herholz, K, Turner, C, Synek, B J, Curtis, M A, Rivers-Auty, J, Lawrence, C, Kellett, K, Hooper, N, Vardy, E R L C, Wu, D, Unwin, R, Faull, R L M, Dowsey, A & Cooper, G 2016, ' Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease : metabolic basis for dementia ', Scientific Reports, vol. 6, 27524 . https://doi.org/10.1038/srep27524, https://doi.org/10.1038/srep27524

Impairment of brain-glucose uptake and brain-copper regulation occurs in Alzheimer's disease (AD). Here we sought to further elucidate the processes that cause neurodegeneration in AD by measuring levels of metabolites and metals in brain regions tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a8417fa6ed1a32c3f945ed5d8087f4b7
https://research-information.bris.ac.uk/en/publications/856aa191-b3d7-4100-85b7-48bd2ea32754

Zobrazit plný text záznamu

Assessment of plasma acylcarnitines before and after weight loss in obese subjects

Autor: Sander M. Houten, Peter R. Murgatroyd, Maarten R. Soeters, Graeme K. Ambler, Chong Y Tan, Marieke G. Schooneman, Samuel Virtue, Sam R Miller, Carla E. M. Hollak, Antonio Vidal-Puig, Antonella Napolitano, Derek J. Nunez

Publikováno v: Schooneman, M G, Napolitano, A, Houten, S M, Ambler, G K, Murgatroyd, P R, Miller, S R, Hollak, C E M, Tan, C Y, Virtue, S, Vidal-Puig, A, Nunez, D J & Soeters, M R 2016, ' Assessment of plasma acylcarnitines before and after weight loss in obese subjects ', Archives of Biochemistry and Biophysics, vol. 606, pp. 73-80 . https://doi.org/10.1016/j.abb.2016.07.013
Archives of biochemistry and biophysics, 606, 73-80. Academic Press Inc.

Acylcarnitines, fatty acid oxidation (FAO) intermediates, have been implicated in diet-induced insulin resistance and type 2 diabetes mellitus, as increased levels are found in obese insulin resistant humans. Moreover plasma acylcarnitines have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e4591a99cd16601c10a5581b8afd91
https://pubmed.ncbi.nlm.nih.gov/27444119

Zobrazit plný text záznamu

Nisin Production Of Lactococcus Lactis N8 With Hemin-Stimulated Cell Respiration In Fed-Batch Fermentation System

Autor: Ömer Şimşek, Burcu Kördikanlioğlu, Per E. J. Saris

In this study, nisin production of Lactococcus lactis N8 was optimized by independent variables of glucose, hemin and oxygen concentrations in fed-batch fermentation in which respiration of cells was stimulated with hemin. Response surface model was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7416a749e37f1ab4345c1f07e3f08f
https://aperta.ulakbim.gov.tr/record/83197

Zobrazit plný text záznamu

LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol

Autor: Anete Dudele, Bjørn Richelsen, Lars Porskjær Christensen, Sten Lund, Morten Poulsen, Mark K. Nøhr, Niels Jessen, Yulia Radko, Steen B. Pedersen, Lene Hyldahl Ebbesen

Publikováno v: Nøhr, M K, Dudele, A, Poulsen, M M, Ebbesen, L H, Radko, Y, Christensen, L P, Jessen, N, Richelsen, B, Lund, S & Pedersen, S B 2016, ' LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol ', PLOS ONE, vol. 11, no. 1, e0146840 . https://doi.org/10.1371/journal.pone.0146840
Nøhr, M K, Dudele, A, Poulsen, M M, Ebbesen, L H, Radko, Y, Christensen, L P, Jessen, N, Richelsen, B, Lund, S & Pedersen, S B 2016, ' LPS-enhanced glucose-stimulated insulin secretion is normalized by resveratrol ', P L o S One, vol. 11, no. 1, e0146840 . https://doi.org/10.1371/journal.pone.0146840
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0146840 (2016)

Low-grade inflammation is seen with obesity and is suggested to be a mediator of insulin resistance. The eliciting factor of low-grade inflammation is unknown but increased permeability of gut bacteria-derived lipopolysaccharides (LPS) resulting in e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718879a591046c7603e7e29f8f2f9132
https://doi.org/10.1371/journal.pone.0146840

Zobrazit plný text záznamu

Rapid profiling of intact glucosinolates in Arabidopsis leaves by UHPLC-QTOFMS using a charged surface hybrid column

Autor: Glauser, G., Schweizer, F., Turlings, T.C., Reymond, P.

Publikováno v: Phytochemical Analysis, vol. 23, no. 5, pp. 520-528

INTRODUCTION: The analysis of glucosinolates (GS) is traditionally performed by reverse-phase liquid chromatography coupled to ultraviolet detection after a time-consuming desulphation step, which is required for increased retention. Simpler and more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::32d4660bac54972e363c56582713387c
https://pubmed.ncbi.nlm.nih.gov/22323091

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání