Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gluconeogenesis Inhibition"'
Akademický článek
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Akademický článek
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Autor:
Fei Ma, Yinan Zhang, Min Lei, Jian Liu, Lihong Hu, Xu Shen, Tingting Zhou, Xiachang Wang, Jing Chen
Publikováno v:
European Journal of Medicinal Chemistry. 152:307-317
Type 2 diabetes mellitus (T2DM) is a chronic, complex and multifactorial metabolic disorder, and targeting gluconeogenesis inhibition is a promising strategy for anti-diabetic drug discovery. This study discovered a new class of thieno[2,3-b]pyridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b8f8329075bbc148a0e8d0bedb621f
https://doi.org/10.1016/j.ejmech.2018.04.028
https://doi.org/10.1016/j.ejmech.2018.04.028
Autor:
Rachel Mata, Fernanda Espinoza-Hernández, Sonia Escandón-Rivera, Gerardo Mata-Torres, Adolfo Andrade-Cetto
Publikováno v:
Journal of Ethnopharmacology. 279:114339
Ethnopharmacological relevance Eryngium cymosum F. Delaroche was detected as a traditional remedy against type 2 diabetes consumed by patients of Tlanchinol in the state of Hidalgo, Mexico. Aim of the study. Assessing the hypoglycemic effect and safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d5ae54b89ae0d0680973c4b5f8c13a
https://doi.org/10.1016/j.jep.2021.114339
https://doi.org/10.1016/j.jep.2021.114339
Akademický článek
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Autor:
Xin Xu, Xu Shen, Vatcharin Rukachaisirikul, Lihong Hu, Xiaodan Guo, Liang Yu, Te Du, Tingting Zhou, Jing Chen, Fei Ma, Xiaofan Shi, Gaihong Wang
Publikováno v:
Journal of Molecular Endocrinology. 59:151-169
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with complicated pathogenesis and targeting gluconeogenesis inhibition is a promising strategy for anti-diabetic drug discovery. G protein-coupled receptors (GPCRs) are classified as dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b54cc328cc8c6d04665af797b9450b4
https://doi.org/10.1530/jme-17-0121
https://doi.org/10.1530/jme-17-0121
Autor:
Paulo Francisco Veiga Bizerra, Jorgete Constantin, Anilda Rufino de Jesus Santos Guimarães, Eduardo Hideo Gilglioni, Rodrigo Polimeni Constantin, Camila Araújo Miranda, Marcos A. Maioli, Fábio Erminio Mingatto, Karina Sayuri Utsunomiya, Emy Luiza Ishii-Iwamoto
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2020-12-12T02:34:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Imidacloprid (IMD) is a neonicotinoid insecticide widely used in crops, pet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480710bbb59205c1d51fd43d03fe294d
https://pubmed.ncbi.nlm.nih.gov/32284125
https://pubmed.ncbi.nlm.nih.gov/32284125
Autor:
Fabio Rebecchi
Metformin is the best therapeutic choice for treating type 2 Diabetes.Despite this, and the fact it has been prescribed worldwide for decades, its mechanism of gluconeogenesis inhibition is still unknown.In the following work a novel mechanism of inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6857bc5ecd1b73250e461ff848725d8
Autor:
Mellina da Silva Simões, Jurandir Fernando Comar, Lívia Bracht, Angela Valderrama Parizotto, Rosane Marina Peralta, Adelar Bracht
Publikováno v:
Environmental toxicology and pharmacology. 54
A systematic study on the effects of diuron on the hepatic metabolism was conducted with emphasis on parameters linked to energy metabolism. The experimental system was the isolated perfused rat liver. The results demonstrate that diuron inhibited bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4d8ba4198efec3aa511dff04460d70
https://pubmed.ncbi.nlm.nih.gov/28683350
https://pubmed.ncbi.nlm.nih.gov/28683350
Autor:
Jurandir Fernando Comar, Adelar Bracht, Israel Souza Santos, Amarilis Giaretta de Moraes, Rosane Marina Peralta, Gabrielle Jacklin Eler
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 29:157-164
The alkyl gallates are found in several natural and industrial products. In the latter products, these compounds are added mainly for preventing oxidation. In the present work, the potencies of methyl gallate, n-propyl gallate, n-pentyl gallate, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12df7ffcea97f968fb2a25334d425052
https://doi.org/10.1002/jbt.21680
https://doi.org/10.1002/jbt.21680