Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gloster B. Aaron"'
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237426 (2020)
Transplantation of human embryonic stem cell (hESC)-derived neural progenitors is a potential treatment for neurological disorders, but relatively little is known about the time course for human neuron maturation after transplantation and the emergen
Externí odkaz:
https://doaj.org/article/52216234243143d6878ae6f5eb681cd7
Autor:
Carolyn Elizabeth Dundes, Laura Grabel, Meghan A. Van Zandt, Daniel B. Lawrence, Christopher Y. Chen, Gloster B. Aaron, Felicia A. Harrsch, Trinithas Boyi, Swechhya Shrestha, Janice R. Naegele, Nickesha C. Anderson, Jyoti Gupta
Publikováno v:
Stem Cell Research, Vol 33, Iss, Pp 83-94 (2018)
GABAergic interneuron dysfunction has been implicated in temporal lobe epilepsy (TLE), autism, and schizophrenia. Inhibitory interneuron progenitors transplanted into the hippocampus of rodents with TLE provide varying degrees of seizure suppression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc16e183dfd5d6216ab06ab7a464835
https://doi.org/10.1016/j.scr.2018.10.007
https://doi.org/10.1016/j.scr.2018.10.007
Publikováno v:
Methods in Molecular Biology ISBN: 9781071608296
This paper describes research methods to investigate the development of synaptic connections between transplanted GABAergic interneurons and endogenous neurons in the adult mouse hippocampus. Our protocol highlights methods for retroviral labeling ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb2ffa548b406986a136b79a278a292
https://doi.org/10.1007/978-1-0716-0830-2_15
https://doi.org/10.1007/978-1-0716-0830-2_15
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2191
This paper describes research methods to investigate the development of synaptic connections between transplanted GABAergic interneurons and endogenous neurons in the adult mouse hippocampus. Our protocol highlights methods for retroviral labeling ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfb300726ca56ea151958d4a29e95494
https://pubmed.ncbi.nlm.nih.gov/32865749
https://pubmed.ncbi.nlm.nih.gov/32865749
Adult male zebra finches (Taeniopygia guttata) continually incorporate adult-born neurons into HVC, a telencephalic brain region necessary for the production of learned song. These neurons express immediate early genes during song production, suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf6fbb9a2700cca1f7e547e62aeff2a
https://doi.org/10.1101/2020.08.31.271783
https://doi.org/10.1101/2020.08.31.271783
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0237426 (2020)
PLoS ONE, Vol 15, Iss 8, p e0237426 (2020)
Transplantation of human embryonic stem cell (hESC)-derived neural progenitors is a potential treatment for neurological disorders, but relatively little is known about the time course for human neuron maturation after transplantation and the emergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919e73323af77bd3dfe96e77d5786a7a
https://doi.org/10.1371/journal.pone.0237426
https://doi.org/10.1371/journal.pone.0237426
Autor:
Jake E Radell, Jyoti Gupta, Bryan W. Luikart, Janice R. Naegele, Gloster B. Aaron, Muhammad N. Arshad, Mark Bromwich, Selena Gonzalez
Publikováno v:
eNeuro. 6(2)
The dentate gyrus (DG) is a region of the adult rodent brain that undergoes continuous neurogenesis. Seizures and loss or dysfunction of GABAergic synapses onto adult-born dentate granule cells (GCs) alter their dendritic growth and migration, result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fed252ed7a6eb53d29b6d9c4d5a965
https://pubmed.ncbi.nlm.nih.gov/31740434
https://pubmed.ncbi.nlm.nih.gov/31740434
Autor:
Elizabeth Litvina, Gloster B. Aaron, Laura Grabel, Stephanie Tagliatela, Xu Maisano, Janice R. Naegele
Publikováno v:
The Journal of Neuroscience. 32:46-61
Cell therapies for neurological disorders require an extensive knowledge of disease-associated neuropathology and procedures for generating neurons for transplantation. In many patients with severe acquired temporal lobe epilepsy (TLE), the dentate g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a47a25434052ee204c3b4caee9abee
https://doi.org/10.1523/jneurosci.2683-11.2012
https://doi.org/10.1523/jneurosci.2683-11.2012
Autor:
Jeffrey Walker, Stephen W. Briggs, Paul J. Lombroso, Janice R. Naegele, Gloster B. Aaron, Kemal Asik
Publikováno v:
Epilepsia. 52:497-506
SUMMARY Purpose: To investigate whether striatal enriched protein tyrosine phosphatase (STEP) influences ictogenesis. Methods: STEP knockout mice were compared to wildtype (WT) mice in pilocarpine-induced seizures. Hippocampal slices were also prepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f41b5e444e0f762b3233103dbaf5d8f3
https://doi.org/10.1111/j.1528-1167.2010.02912.x
https://doi.org/10.1111/j.1528-1167.2010.02912.x