Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gloriia Novikova"'
Autor:
Anna Podleśny-Drabiniok, Gloriia Novikova, Yiyuan Liu, Josefine Dunst, Rose Temizer, Chiara Giannarelli, Samuele Marro, Taras Kreslavsky, Edoardo Marcora, Alison Mary Goate
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Genetic and experimental evidence suggests that Alzheimer’s disease (AD) risk alleles and genes may influence disease susceptibility by altering the transcriptional and cellular responses of macrophages, including microglia, to damage of l
Externí odkaz:
https://doaj.org/article/027d5a15040d494d9ba7883e1eb3c81b
Autor:
Manav Kapoor, Michael J. Chao, Emma C. Johnson, Gloriia Novikova, Dongbing Lai, Jacquelyn L. Meyers, Jessica Schulman, John I. Nurnberger, Bernice Porjesz, Yunlong Liu, The Collaborative Study on the Genetics of Alcoholism (COGA), Tatiana Foroud, Howard J. Edenberg, Edoardo Marcora, Arpana Agrawal, Alison Goate
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Alcohol use disorder and drinks per week both have been studied genetically and have different correlations with psychiatric diseases. Here the authors integrate multi-omics data to identify unique and shared variants, genes and pathways for alcohol
Externí odkaz:
https://doaj.org/article/2f7874ae384e400ab64698142f8c1fce
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-13 (2021)
Abstract Alzheimer’s disease (AD) is the most common type of dementia, affecting millions of people worldwide; however, no disease-modifying treatments are currently available. Genome-wide association studies (GWASs) have identified more than 40 lo
Externí odkaz:
https://doaj.org/article/5e01f228869c40fe8c9360db728db89c
Autor:
Gloriia Novikova, Manav Kapoor, Julia TCW, Edsel M. Abud, Anastasia G. Efthymiou, Steven X. Chen, Haoxiang Cheng, John F. Fullard, Jaroslav Bendl, Yiyuan Liu, Panos Roussos, Johan LM Björkegren, Yunlong Liu, Wayne W. Poon, Ke Hao, Edoardo Marcora, Alison M. Goate
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
This study integrates Alzheimer’s disease (AD) GWAS data with myeloid cell genomics, and reports that myeloid active enhancers are most burdened by AD risk alleles. The authors also nominate candidate causal regulatory elements, variants and genes
Externí odkaz:
https://doaj.org/article/e7ee804a940645c0aa0e698c50c1d0da
Autor:
Anna Podlesny-Drabiniok, Gloriia Novikova, Yiyuan Liu, Josefine Dunst, Rose Temizer, Chiara Giannarelli, Samuele Marro, Taras Kreslavsky, Edoardo Marcora, Alison Mary Goate
Publikováno v:
bioRxiv
BackgroundGenetic and experimental evidence strongly implicates myeloid cells in the etiology of AD and suggests that AD-associated alleles and genes may modulate disease risk by altering the transcriptional and cellular responses of macrophages (lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efaa3ba163f13c65ac90a656ff4378a
https://europepmc.org/articles/PMC9948946/
https://europepmc.org/articles/PMC9948946/
Autor:
John F. Crary, Katia de Paiva Lopes, Bradley T. Hyman, Manav Kapoor, Gloriia Novikova, Jonathan D. Glass, Valeriy Borukov, Hadley Walsh, Erin E. Franklin, Johannes Attems, Sara Shuldberg, Shea J. Andrews, Thomas J. Montine, Julie A. Schneider, Jonathan D. Cherry, C. Dirk Keene, Towfique Raj, Charles L. White, Thor D. Stein, Evan Udine, Gai Ayalon, Thao Pham, Maria M. Corrada, Weijing Tang, Ann C. McKee, Bess Frost, Marco M. Hefti, Qinwen Mao, Lei Yu, Patrick R. Hof, Peter T. Nelson, Elias M. Gonzalez, Alan E. Renton, Corey T. McMillan, Jack Humphrey, Natalia Han, Margaret E. Flanagan, SoongHo Kim, Etty Cortes, Megan A. Iida, Inma Cobos, Jeff Metcalf, Sandra Weintraub, Julie Hunkapiller, Diana K. Dangoor, Robert A. Rissman, Marcos Otero-Garcia, John Q. Trojanowski, Dushyant P. Purohit, Caitlin S. Latimer, Marla Gearing, Claudia H. Kawas, Kathryn R. Bowles, Wayne W. Poon, Brian Fulton-Howard, Edoardo Marcora, Alison Goate, Alicia Casella, Tushar Bhangale, Richard J. Perrin, Herbert T. Cohen, Bahar Salehi, Gabor G. Kovacs, Andy F. Teich, Mary Sano, Jamie M. Walker, Dennis W. Dickson, Randy Woltjer, Kristen Whitney, M.-Marsel Mesulam, Ricardo Assunção Vialle, Peter Fischer, Kurt Farrell, Jean-Paul Vonsattel, Cheick T. Sissoko, Vahram Haroutunian, Sam Gandy, Mirjam I. Lutz, Matthew P. Frosch, Nigel J. Cairns, Melissa E. Murray, Robert R. Graham, David A. Wolk, Juan C. Troncoso, Garrett Wong, Julia Kofler, Edward B. Lee, Timothy E. Richardson, Thomas G. Beach
Publikováno v:
Acta Neuropathol
Primary age-related tauopathy (PART) is a neurodegenerative pathology with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amnestic cognit
Autor:
Kurt Farrell, SoongHo Kim, Natalia Han, Megan A. Iida, Elias Gonzalez, Marcos Otero-Garcia, Jamie Walker, Tim Richardson, Alan E. Renton, Shea J. Andrews, Brian Fulton-Howard, Jack Humphrey, Ricardo A. Vialle, Kathryn R. Bowles, Kristen Whitney, Diana K. Dangoor, Edoardo Marcora, Marco M. Hefti, Alicia Casella, Cheick Sissoko, Manav Kapoor, Gloriia Novikova, Evan Udine, Garrett Wong, Weijing Tang, Tushar Bhangale, Julie Hunkapiller, Gai Ayalon, Rob Graham, Jonathan D. Cherry, Etty Cortes, Valeriy Borukov, Ann C. McKee, Thor D. Stein, Jean-Paul Vonsattel, Andy F. Teich, Marla Gearing, Jonathan Glass, Juan C. Troncoso, Matthew P. Frosch, Bradley T. Hyman, Dennis W. Dickson, Melissa E. Murray, Johannes Attems, Margaret E. Flanagan, Qinwen Mao, M-Marsel Mesulam, Sandra Weintraub, Randy Woltjer, Thao Pham, Julia Kofler, Julie A. Schneider, Lei Yu, Dushyant P. Purohit, Vahram Haroutunian, Patrick R. Hof, Sam Gandy, Mary Sano, Thomas G. Beach, Wayne Poon, Claudia Kawas, María Corrada, Robert A. Rissman, Jeff Metcalf, Sara Shuldberg, Bahar Salehi, Peter T. Nelson, John Q. Trojanowski, Edward B. Lee, David A. Wolk, Corey T. McMillan, Dirk C. Keene, Thomas J. Montine, Gabor G. Kovacs, Mirjam I. Lutz, Peter Fischer, Richard J. Perrin, Nigel Cairns, Erin E. Franklin, Herbert T. Cohen, Maria Inmaculada Cobos Sillero, Bess Frost, Towfique Raj, Alison Goate, Charles L. White, John F. Crary
Primary age-related tauopathy (PART) is a neurodegenerative tauopathy with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amnestic cognit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::262f58b1d732e33d60c6e7e337f43e85
https://doi.org/10.1101/2021.06.30.450599
https://doi.org/10.1101/2021.06.30.450599
Autor:
Manav Kapoor, Wayne W. Poon, Edsel M. Abud, John F. Fullard, Jaroslav Bendl, Yunlong Liu, Alison Goate, Edoardo Marcora, Julia Tcw, Panos Roussos, Anastasia G. Efthymiou, Johan L.M. Björkegren, Ke Hao, Yiyuan Liu, Steven X. Chen, Gloriia Novikova, Haoxiang Cheng
Publikováno v:
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer’s disease (AD), but the causal variants, regulatory elements, genes and pathways remain largely unknown, impeding a mechanistic understanding of AD p
Autor:
Anastasia M. Efthymiou, Panos Roussos, Ke Hao, Alan E. Renton, Wayne W. Poon, Jaroslav Bendl, Haoxiang M. Cheng, Alison Goate, Edoardo Marcora, Julia T.C.W., John F. Fullard, Gloriia Novikova, Manav Kapoor, Edsel M. Abud
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
John F. Fullard, Alison Goate, Anastasia M. Efthymiou, Wayne W. Poon, Gloriia Novikova, Julia Tcw, Manav Kapoor, Ke Hao, Jaroslav Bendl, Edoardo Marcora, Haoxiang M. Cheng, Panos Roussos, Edsel M. Abud, Alan E. Renton
Publikováno v:
Alzheimer's & Dementia. 16