Zobrazeno 1 - 10
of 1 065
pro vyhledávání: '"Gloria V"'
Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptations
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Deregulation of tumor cell metabolism is widely recognized as a “hallmark of cancer.” Many of the selective pressures encountered by tumor cells, such as exposure to anticancer therapies, navigation of the metastatic cascade, and communication wi
Externí odkaz:
https://doaj.org/article/797819a65faf4f8f8c019ce148927a74
Autor:
Gloria V. Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B. Redwood, Yan Jiang, Aaron McCoy, Amanda L. Rinkenbaugh, Rosanna Lau, Alexander J. Trevarton, Chunxiao Fu, Rebekah Gould, Elizabeth E. Ravenberg, Lei Huo, Rosalind Candelaria, Lumarie Santiago, Beatriz E. Adrada, Deanna L. Lane, Gaiane M. Rauch, Wei T. Yang, Jason B. White, Jeffrey T. Chang, Stacy L. Moulder, W. Fraser Symmans, Susan G. Hilsenbeck, Helen Piwnica-Worms
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Patient-derived xenograft (PDX) models of breast cancer are an effective discovery platform and tool for preclinical pharmacologic testing and biomarker identification. We established orthotopic PDX models of triple negative breast cancer (T
Externí odkaz:
https://doaj.org/article/1aeaec90b47b427c8b0d10b0dad9ddf6
Autor:
Santiago M. Ruatta, Denis N. Prada Gori, Martín Fló Díaz, Franca Lorenzelli, Karen Perelmuter, Lucas N. Alberca, Carolina L. Bellera, Andrea Medeiros, Gloria V. López, Mariana Ingold, Williams Porcal, Estefanía Dibello, Irina Ihnatenko, Conrad Kunick, Marcelo Incerti, Martín Luzardo, Maximiliano Colobbio, Juan Carlos Ramos, Eduardo Manta, Lucía Minini, María Laura Lavaggi, Paola Hernández, Jonas Šarlauskas, César Sebastian Huerta García, Rafael Castillo, Alicia Hernández-Campos, Giovanni Ribaudo, Giuseppe Zagotto, Renzo Carlucci, Noelia S. Medrán, Guillermo R. Labadie, Maitena Martinez-Amezaga, Carina M. L. Delpiccolo, Ernesto G. Mata, Laura Scarone, Laura Posada, Gloria Serra, Theodora Calogeropoulou, Kyriakos Prousis, Anastasia Detsi, Mauricio Cabrera, Guzmán Alvarez, Adrián Aicardo, Verena Araújo, Cecilia Chavarría, Lucija Peterlin Mašič, Melisa E. Gantner, Manuel A. Llanos, Santiago Rodríguez, Luciana Gavernet, Soonju Park, Jinyeong Heo, Honggun Lee, Kyu-Ho Paul Park, Mariela Bollati-Fogolín, Otto Pritsch, David Shum, Alan Talevi, Marcelo A. Comini
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The identification of chemical compounds that interfere with SARS-CoV-2 replication continues to be a priority in several academic and pharmaceutical laboratories. Computational tools and approaches have the power to integrate, process
Externí odkaz:
https://doaj.org/article/37a7aaacc38c4e40801eaddd5b8743ba
Autor:
Hillary Stires, Igor Bado, Thelma Brown, Martha Carlson, Isaac S. Chan, Gloria V. Echeverria, Andrew J. Ewald, Bora Lim, Carla Lloyd, Julia Maues, Steffi Oesterreich, Robert N. Riter, Kelly Shanahan, Alana L. Welm, Josh Newby
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-5 (2022)
Abstract Including patient advocates in basic cancer research ensures that breast cancer research is intentional, supports effective communication with broader audiences, and directly connects researchers with those who they are striving to help. Des
Externí odkaz:
https://doaj.org/article/f2333b9b76f7493082dff1a374d8ec46
Autor:
Juan Vivanco‐Suarez, Adam N. Wallace, Sudeepta Dandapat, Gloria V. Lopez, Aldo Mendez‐Ruiz, Yasha Kayan, Alexander Z. Copelan, Andres Dajles, Cynthia B. Zevallos, Darko Quispe‐Orozco, Alan Mendez‐Ruiz, Milagros Galecio‐Castillo, Edgar A. Samaniego, Mudassir Farooqui, Josser E. Delgado, Santiago Ortega‐Gutierrez
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 1 (2023)
Background Balloon‐assisted coiling (BAC) and stent‐assisted coiling (SAC) have been established as feasible approaches to manage ruptured wide‐necked intracranial aneurysms. Antiplatelet medications used with SAC theoretically increase risk of
Externí odkaz:
https://doaj.org/article/3260029b36c244b2abdc3623ca73119e
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Subclonal heterogeneity and evolution are characteristics of breast cancer that play a fundamental role in tumour development, progression and resistance to current therapies. In this review, we focus on the recent advances in understanding
Externí odkaz:
https://doaj.org/article/dbfbbdf73e7441ab9e9cae05248cd3bf
Autor:
María Varela, Miriam López, Mariana Ingold, Diego Alem, Valentina Perini, Karen Perelmuter, Mariela Bollati-Fogolín, Gloria V. López, Paola Hernández
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 199 (2023)
Bladder cancer is a worldwide problem and improved therapies are urgently needed. In the search for newer strong antitumor compounds, herein, we present the study of three nitric oxide-releasing compounds and evaluate them as possible therapies for t
Externí odkaz:
https://doaj.org/article/e0bf9dbe2041417daa743742051e7308
Autor:
Kevin Roarty, Gloria V. Echeverria
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
While numerous therapies are highly efficacious in early-stage breast cancers and in particular subsets of breast cancers, therapeutic resistance and metastasis unfortunately arise in many patients. In many cases, tumors that are resistant to standar
Externí odkaz:
https://doaj.org/article/b0450c5ed5f243e7a6cd822534741451
Autor:
Rosina Dapueto, Jorge Rodriguez-Duarte, Germán Galliussi, Andrés Kamaid, Mariana Bresque, Carlos Batthyány, Gloria V. López, Carlos Escande
Publikováno v:
Redox Biology, Vol 39, Iss , Pp 101833- (2021)
Chronic metabolic diseases, like obesity, type II diabetes and atherosclerosis often involve a low-grade and sterile systemic inflammatory state, in which activation of the pro-inflammatory transcription factor NF-kB and the NLRP3 inflammasome play a
Externí odkaz:
https://doaj.org/article/fd342c50fe4445279342c16afc73566b
Autor:
Mariana Ingold, Victoria de la Sovera, Rosina Dapueto, Paola Hernández, Williams Porcal, Gloria V. López
Publikováno v:
Molecules, Vol 27, Iss 6, p 1756 (2022)
Prostate and bladder cancers are commonly diagnosed malignancies in men. Several nitric oxide donor compounds with strong antitumor activity have been reported. Thus, continuing with our efforts to explore the chemical space around bioactive furoxan
Externí odkaz:
https://doaj.org/article/97dc12439ec24e82970ca1a3c7ee41b3