Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gloria Tobajas"'
Autor:
Gloria Tobajas-Curiel, Qingqing Sun, Jeremy K. M. Sanders, Pablo Ballester, Christopher A. Hunter
Molecular recognition in water involves contributions due to polar functional group interactions, partial desolvation of polar and non-polar surfaces and changes in conformational flexibility, presenting a challenge for rational design and interpreta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6f56254068c257ecd2fd1417f3105d
Autor:
Giancarlo Fabrizi, Daniele Passarella, Viviana Cuartas, Gloria Tobajas, Isabella Screpanti, Francesca Ghirga, Michael S. Christodoulou, Eva-María Priego, Marta Gargantilla, Bruno Botta, Mattia Mori, Deborah Quaglio, Silvia Balducci, Álvaro Carmona Pestaña, Rocco Palermo, María-Jesús Pérez-Pérez, Nadezda Zhdanovskaya
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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instname
Based on hit-likeness and chemical diversity, a number of chalcones and chalcone-mimetic compounds were selected as putative Notch inhibitors. The evaluation of the antiproliferative effect combined with the inhibition of Notch1 expression in KOPTK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33cda1cd686244e699c44ac2bac3572
http://hdl.handle.net/10261/184679
http://hdl.handle.net/10261/184679
Autor:
Ernesto Quesada, Eva-María Priego, Sam Noppen, María-Jesús Pérez-Pérez, Oskía Bueno, Sandra Liekens, Juan Estévez-Gallego, María-José Camarasa, Gloria Tobajas, José-Fernando Díaz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Based on the conformation of the α-methyl chalcone TUB091 in its complex with tubulin, a series of conformational mimetics have been designed and synthesized where the methyl group of the chalcone has been fused to phenyl ring B resulting in 1,2,3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7115a69ae845ac20d146ec543fa106c1
http://hdl.handle.net/10261/170941
http://hdl.handle.net/10261/170941