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of 4
pro vyhledávání: '"Gloria Sanchez-Castaño"'
Autor:
M. Montalar-Montero, Marival Bermejo, M. Rodriguez-Ibanez, Gloria Sanchez-Castaño, Virginia Merino, Teresa María Garrigues
Publikováno v:
International Journal of Pharmaceutics. 307:33-41
The efflux process due to p-glycoprotein-like mechanisms of ciprofloxacin (CIP) and grepafloxacin (GRX) has been studied “in situ” in rats and “in vitro” in Caco-2 cells. The results were modelled by a curve fitting procedure which allowed th
Autor:
Isabel González-Álvarez, Virginia Merino, Amparo Centelles-Sangüesa, Marta González-Álvarez, Davinia Oltra-Noguera, Marival Bermejo, Victor Mangas-Sanjuan, Ignacio González-García, Gloria Sanchez-Castaño, V.G. Casabó
Publikováno v:
Journal of pharmacological and toxicological methods. 71
Introduction In vitro models with high predictive ability have been revealed as strong tools for pharmaceutical industry. However, the variability in permeability estimations complicates the comparison and combination of data from different laborator
Autor:
Gloria Sanchez-Castaño, Ana Belén Ruiz-García, Marival Bermejo, Teresa M. Garriguesx, Joan Freixas, Virginia Merino, J.M. Plá-Delfina, Nuria Bañón
Publikováno v:
Journal of Pharmaceutical Sciences. 89:1395-1403
A preliminary study attempting to predict the intrinsic absolute bioavailability of a group of antibacterial 6-fluoroquinolones-including true and imperfect homologues as well as heterologues-was carried out. The intrinsic absolute bioavailability of
Autor:
Joan Freixas, Gloria Sanchez-Castaño, T.M. Garrigues, Marival Bermejo, Ana Belén Ruiz-García, Virginia Merino
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 48(3)
The study demonstrates that the oral extent of bioavailability of flumequine in the rat, relative to the intravenous injection, is complete (0.94±0.04) and not significantly different from that found by the intraduodenal route (0.95±0.04). The rate