Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Gloria S, Pryhuber"'
Autor:
Nam D. Nguyen, Lorena Rosas, Timur Khaliullin, Peiran Jiang, Euxhen Hasanaj, Jose A. Ovando-Ricardez, Marta Bueno, Irfan Rahman, Gloria S. Pryhuber, Dongmei Li, Qin Ma, Toren Finkel, Melanie Königshoff, Oliver Eickelberg, Mauricio Rojas, Ana L. Mora, Jose Lugo-Martinez, Ziv Bar-Joseph
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract The low resolution of spatial transcriptomics data necessitates additional information for optimal use. We developed scDOT, which combines spatial transcriptomics and single cell RNA sequencing to improve the ability to reconstruct single ce
Externí odkaz:
https://doaj.org/article/2220c040f71d4876ae3c2f1dae637a9f
Autor:
Dharmesh V. Hirani, Florian Thielen, Siavash Mansouri, Soula Danopoulos, Christina Vohlen, Pinar Haznedar-Karakaya, Jasmine Mohr, Rebecca Wilke, Jaco Selle, Thomas Grosch, Ivana Mizik, Margarete Odenthal, Cristina M. Alvira, Celien Kuiper-Makris, Gloria S. Pryhuber, Christian Pallasch, S. van Koningsbruggen-Rietschel, Denise Al-Alam, Werner Seeger, Rajkumar Savai, Jörg Dötsch, Miguel A. Alejandre Alcazar
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-20 (2023)
Abstract Preterm infants with oxygen supplementation are at high risk for bronchopulmonary dysplasia (BPD), a neonatal chronic lung disease. Inflammation with macrophage activation is central to the pathogenesis of BPD. CXCL10, a chemotactic and pro-
Externí odkaz:
https://doaj.org/article/ee974415ba264f109c6c53e3c0e08811
Autor:
Minzhe Guo, Michael P. Morley, Cheng Jiang, Yixin Wu, Guangyuan Li, Yina Du, Shuyang Zhao, Andrew Wagner, Adnan Cihan Cakar, Michal Kouril, Kang Jin, Nathan Gaddis, Joseph A. Kitzmiller, Kathleen Stewart, Maria C. Basil, Susan M. Lin, Yun Ying, Apoorva Babu, Kathryn A. Wikenheiser-Brokamp, Kyu Shik Mun, Anjaparavanda P. Naren, Geremy Clair, Joshua N. Adkins, Gloria S. Pryhuber, Ravi S. Misra, Bruce J. Aronow, Timothy L. Tickle, Nathan Salomonis, Xin Sun, Edward E. Morrisey, Jeffrey A. Whitsett, NHLBI LungMAP Consortium, Yan Xu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Accurate cell type identification is a key and rate-limiting step in single-cell data analysis. Single-cell references with comprehensive cell types, reproducible and functionally validated cell identities, and common nomenclatures are much
Externí odkaz:
https://doaj.org/article/3956b6ba8fe5414badfff8310d969b64
Autor:
Fabio Zanini, Xibing Che, Carsten Knutsen, Min Liu, Nina E. Suresh, Racquel Domingo-Gonzalez, Steve H. Dou, Daoqin Zhang, Gloria S. Pryhuber, Robert C. Jones, Stephen R. Quake, David N. Cornfield, Cristina M. Alvira
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106097- (2023)
Summary: At birth, the lung is still immature, heightening susceptibility to injury but enhancing regenerative capacity. Angiogenesis drives postnatal lung development. Therefore, we profiled the transcriptional ontogeny and sensitivity to injury of
Externí odkaz:
https://doaj.org/article/b26cc1b660b54915931e23d68f0719cc
Autor:
Raven M Osborn, Justin Leach, Michelle Zanche, John M Ashton, ChinYi Chu, Juilee Thakar, Stephen Dewhurst, Sonia Rosenberger, Martin Pavelka, Gloria S Pryhuber, Thomas J Mariani, Christopher S Anderson
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281898 (2023)
Coronavirus disease (COVID-19) is an infectious disease caused by the SARS coronavirus 2 (SARS-CoV-2) virus. Direct assessment, detection, and quantitative analysis using high throughput methods like single-cell RNA sequencing (scRNAseq) is imperativ
Externí odkaz:
https://doaj.org/article/33be82a1206d4e5589990a653d121e5b
Autor:
Jessica K. Lukowski, Heather Olson, Marija Velickovic, Juan Wang, Jennifer E. Kyle, Young-Mo Kim, Sarah M. Williams, Ying Zhu, Heidi L. Huyck, Matthew D. McGraw, Cory Poole, Lisa Rogers, Ravi Misra, Theodore Alexandrov, Charles Ansong, Gloria S. Pryhuber, Geremy Clair, Joshua N. Adkins, James P. Carson, Christopher R. Anderton
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Human disease states are biomolecularly multifaceted and can span across phenotypic states, therefore it is important to understand diseases on all levels, across cell types, and within and across microanatomical tissue compartments. To obtain an acc
Externí odkaz:
https://doaj.org/article/71c4b1bf9f7543368a50ac18854fd16f
Autor:
Amelia Freeman, Luhua Qiao, Nelida Olave, Gabriel Rezonzew, Samuel Gentle, Brian Halloran, Gloria S. Pryhuber, Amit Gaggar, Trent E. Tipple, Namasivayam Ambalavanan, Charitharth Vivek Lal
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background MicroRNA (miR) are small conserved RNA that regulate gene expression post-transcription. Previous genome-wide analysis studies in preterm infants indicate that pathways of miR 219-5p are important in infants with Bronchopulmonary
Externí odkaz:
https://doaj.org/article/a77a493e93a84952b8f9d5217a92c176
Autor:
Andrew McDavid, Nathan Laniewski, Alex Grier, Ann L. Gill, Haeja A. Kessler, Heidie Huyck, Elizabeth Carbonell, Jeanne Holden-Wiltse, Sanjukta Bandyopadhyay, Jennifer Carnahan, Andrew M. Dylag, David J. Topham, Ann R. Falsey, Mary T. Caserta, Gloria S. Pryhuber, Steven R. Gill, Kristin M. Scheible
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104007- (2022)
Summary: Neonatal immune-microbiota co-development is poorly understood, yet age-appropriate recognition of – and response to – pathogens and commensal microbiota is critical to health. In this longitudinal study of 148 preterm and 119 full-term
Externí odkaz:
https://doaj.org/article/dc890ebcbe60431d83a0f7f363235879
Autor:
Ethan David Cohen, Min Yee, George A. Porter Jr., Erin Ritzer, Andrew N. McDavid, Paul S. Brookes, Gloria S. Pryhuber, Michael A. O’Reilly
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Preterm birth increases the risk for pulmonary hypertension and heart failure in adulthood. Oxygen therapy can damage the immature cardiopulmonary system and may be partially responsible for the cardiovascular disease in adults born preterm. We previ
Externí odkaz:
https://doaj.org/article/52549453edfd42f29d70d399ca47d15f
Autor:
Andrew McDavid, Anthony M. Corbett, Jennifer L. Dutra, Andrew G. Straw, David J. Topham, Gloria S. Pryhuber, Mary T. Caserta, Steven R. Gill, Kristin M. Scheible, Jeanne Holden-Wiltse
Publikováno v:
Journal of Clinical and Translational Science, Vol 5 (2021)
Abstract Introduction: In clinical and translational research, data science is often and fortuitously integrated with data collection. This contrasts to the typical position of data scientists in other settings, where they are isolated from data col
Externí odkaz:
https://doaj.org/article/10cdfb957fba423facac718494418246