Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Gloria Manzotti"'
Autor:
Emanuele Vitale, Veronica Manicardi, Mila Gugnoni, Federica Torricelli, Benedetta Donati, Silvia Muccioli, Elisa Salviato, Teresa Rossi, Gloria Manzotti, Simonetta Piana, Alessia Ciarrocchi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-13 (2024)
Abstract Recent insights into the mechanisms controlling gene expression identified enhancer-associated long non-coding RNAs (elncRNAs) as master players of transcription in cancers. RUNX2, a mammalian RUNT-related transcription factor, is increasing
Externí odkaz:
https://doaj.org/article/b9de6d6aa9c140608d700db3b2baccb8
Autor:
Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrochi, Roberto Piva, Antonino Neri
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Multiple myeloma (MM) is a dreadful disease, marked by the uncontrolled proliferation of clonal plasma cells (PCs) within the bone marrow (BM). MM is characterized by a highly heterogeneous clinical and molecular background, supported by severe genom
Externí odkaz:
https://doaj.org/article/14498b0f3bfd45faa9f5c4dd0eecdaa1
Autor:
Veronica Manicardi, Mila Gugnoni, Elisabetta Sauta, Benedetta Donati, Emanuele Vitale, Federica Torricelli, Gloria Manzotti, Simonetta Piana, Caterina Longo, Francesco Ghini, Alessia Ciarrocchi
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2728-2742 (2023)
Mortality from vmelanoma is associated with metastatic disease, but the mechanisms leading to spreading of the cancer cells remain obscure. Spatial profiling revealed that melanoma is characterized by a high degree of heterogeneity, which is establis
Externí odkaz:
https://doaj.org/article/34e4c8d01a8944a59fdd35259b0fe025
Autor:
Mila Gugnoni, Eugenia Lorenzini, Italo Faria do Valle, Daniel Remondini, Gastone Castellani, Federica Torricelli, Elisabetta Sauta, Benedetta Donati, Moira Ragazzi, Francesco Ghini, Simonetta Piana, Alessia Ciarrocchi, Gloria Manzotti
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-12 (2023)
Abstract Anaplastic Thyroid Cancer (ATC) is the most aggressive and de-differentiated subtype of thyroid cancer. Many studies hypothesized that ATC derives from Differentiated Thyroid Carcinoma (DTC) through a de-differentiation process triggered by
Externí odkaz:
https://doaj.org/article/e983952e3be54fcdb0f46d506bbeff05
Autor:
Mila Gugnoni, Gloria Manzotti, Emanuele Vitale, Elisabetta Sauta, Federica Torricelli, Francesca Reggiani, Mariaelena Pistoni, Simonetta Piana, Alessia Ciarrocchi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Abstract Background Anaplastic Thyroid Cancer (ATC) is an undifferentiated and aggressive tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans-differentiation process. Epithelial-to-Mesenchymal Transition (EMT)
Externí odkaz:
https://doaj.org/article/85748d25b2344aec88b4a003a801b49e
Autor:
Federica Torricelli, Elisabetta Sauta, Veronica Manicardi, Vincenzo Dario Mandato, Andrea Palicelli, Alessia Ciarrocchi, Gloria Manzotti
Publikováno v:
Cells, Vol 12, Iss 5, p 794 (2023)
Background: Endometrial cancer (EC) is the most common gynecologic tumor and the world’s fourth most common cancer in women. Most patients respond to first-line treatments and have a low risk of recurrence, but refractory patients, and those with m
Externí odkaz:
https://doaj.org/article/c0fe1a47c2524934a108fc5e7287df97
Autor:
Annalisa Tameni, Elisabetta Sauta, Valentina Mularoni, Federica Torricelli, Gloria Manzotti, Giorgio Inghirami, Riccardo Bellazzi, Valentina Fragliasso, Alessia Ciarrocchi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Deregulation of chromatin modifiers, including DNA helicases, is emerging as one of the mechanisms underlying the transformation of anaplastic lymphoma kinase negative (ALK−) anaplastic large cell lymphoma (ALCL). We recently identified th
Externí odkaz:
https://doaj.org/article/6176e0167b574916beac8a2bf78dd49a
Autor:
Gloria Manzotti, Federica Torricelli, Benedetta Donati, Valentina Sancisi, Mila Gugnoni, Alessia Ciarrocchi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background RUNX2 is a Runt-related transcription factor required during embryogenesis for skeletal development and morphogenesis of other organs including thyroid and breast gland. Consistent evidence indicates that RUNX2 expression is aberr
Externí odkaz:
https://doaj.org/article/379a70cf1b68498bb56f0bb56ab46479
Autor:
Giovanna Ferrari-Amorotti, Claudia Chiodoni, Fei Shen, Sara Cattelani, Angela Rachele Soliera, Gloria Manzotti, Giulia Grisendi, Massimo Dominici, Francesco Rivasi, Mario Paolo Colombo, Alessandro Fatatis, Bruno Calabretta
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 12, Pp 1047-1058 (2014)
Most triple-negative breast cancers (TNBCs) exhibit gene expression patterns associated with epithelial-to-mesenchymal transition (EMT), a feature that correlates with a propensity for metastatic spread. Overexpression of the EMT regulator Slug is de
Externí odkaz:
https://doaj.org/article/a77b33130f67494ab68695c56d8e7eaa
Autor:
Sara Cattelani, Giovanna Ferrari-Amorotti, Sara Galavotti, Raffaella Defferrari, Barbara Tanno, Samantha Cialfi, Jenny Vergalli, Valentina Fragliasso, Clara Guerzoni, Gloria Manzotti, Angela Rachele Soliera, Chiara Menin, Roberta Bertorelle, Heather P. McDowell, Alessandro Inserra, Maria Luisa Belli, Luigi Varesio, Deborah Tweddle, Gian Paolo Tonini, Pierluigi Altavista, Carlo Dominici, Giuseppe Raschellà, Bruno Calabretta
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 7, Pp 634-643 (2012)
The p53 gene is rarely mutated in neuroblastoma, but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and clinical outcome. We investigated whether this polymorphism affects neuroblastoma risk and disease out
Externí odkaz:
https://doaj.org/article/a82fdf1e4a494fedb36b4d5a5686f82e