Zobrazeno 1 - 10
of 528
pro vyhledávání: '"Gloria M Petersen"'
Autor:
Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso, Oscar Lao, Esther Molina-Montes, Isabel Adoración Martín-Antoniano, Paulina Gómez-Rubio, Rita Lawlor, Alfredo Carrato, Manuel Hidalgo, Mar Iglesias, Xavier Molero, Matthias Löhr, Christopher Michalski, José Perea, Michael O’Rorke, Victor Manuel Barberà, Adonina Tardón, Antoni Farré, Luís Muñoz-Bellvís, Tanja Crnogorac-Jurcevic, Enrique Domínguez-Muñoz, Thomas Gress, William Greenhalf, Linda Sharp, Luís Arnes, Lluís Cecchini, Joaquim Balsells, Eithne Costello, Lucas Ilzarbe, Jörg Kleeff, Bo Kong, Mirari Márquez, Josefina Mora, Damian O’Driscoll, Aldo Scarpa, Weimin Ye, Jingru Yu, PanGenEU Investigators, Montserrat García-Closas, Manolis Kogevinas, Nathaniel Rothman, Debra T Silverman, SBC/EPICURO Investigators, Demetrius Albanes, Alan A Arslan, Laura Beane-Freeman, Paige M Bracci, Paul Brennan, Bas Bueno-de-Mesquita, Julie Buring, Federico Canzian, Margaret Du, Steve Gallinger, J Michael Gaziano, Phyllis J Goodman, Marc Gunter, Loic LeMarchand, Donghui Li, Rachael E Neale, Ulrika Peters, Gloria M Petersen, Harvey A Risch, Maria José Sánchez, Xiao-Ou Shu, Mark D Thornquist, Kala Visvanathan, Wei Zheng, Stephen J Chanock, Douglas Easton, Brian M Wolpin, Rachael Z Stolzenberg-Solomon, Alison P Klein, Laufey T Amundadottir, Marc A Marti-Renom, Francisco X Real, Núria Malats
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic var
Externí odkaz:
https://doaj.org/article/fd82873a71df49c79bdc3dadb14c043b
Autor:
Cavin Wong, Fei Chen, Najmeh Alirezaie, Yifan Wang, Adeline Cuggia, Ayelet Borgida, Spring Holter, Tatiana Lenko, Celine Domecq, Alzheimer’s Disease Neuroimaging Initiative, Gloria M Petersen, Sapna Syngal, Randall Brand, Anil K Rustgi, Michele L Cote, Elena Stoffel, Sara H Olson, Nicholas J Roberts, Mohammad R Akbari, Jacek Majewski, Alison P Klein, Celia M T Greenwood, Steven Gallinger, George Zogopoulos
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008344 (2019)
Pancreatic adenocarcinoma (PC) is a lethal malignancy that is familial or associated with genetic syndromes in 10% of cases. Gene-based surveillance strategies for at-risk individuals may improve clinical outcomes. However, familial PC (FPC) is plagu
Externí odkaz:
https://doaj.org/article/75b4a65526c94ebcb058060e43896286
Autor:
Federico Innocenti, Kouros Owzar, Chen Jiang, Amy S Etheridge, Raluca Gordân, Alexander B Sibley, Flora Mulkey, Donna Niedzwiecki, Dylan Glubb, Nicole Neel, Mark S Talamonti, David J Bentrem, Eric Seiser, Jen Jen Yeh, Katherine Van Loon, Howard McLeod, Mark J Ratain, Hedy L Kindler, Alan P Venook, Yusuke Nakamura, Michiaki Kubo, Gloria M Petersen, William R Bamlet, Robert R McWilliams
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202272 (2018)
PURPOSE:Advanced pancreatic cancer is a highly refractory disease almost always associated with survival of little more than a year. New interventions based on novel targets are needed. We aim to identify new genetic determinants of overall survival
Externí odkaz:
https://doaj.org/article/3e344ee31f6b477ca981d00ace30fd70
Autor:
Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D Figueroa, Victoria K Cortessis, Núria Malats, Margaret R Karagas, Paolo Vineis, I-Shou Chang, Dongxin Lin, Baosen Zhou, Adeline Seow, Keitaro Matsuo, Yun-Chul Hong, Neil E Caporaso, Brian Wolpin, Eric Jacobs, Gloria M Petersen, Alison P Klein, Donghui Li, Harvey Risch, Alan R Sanders, Li Hsu, Robert E Schoen, Hermann Brenner, MGS (Molecular Genetics of Schizophrenia) GWAS Consortium, GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium), GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium, PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium, PanScan Consortium, GAME-ON/ELLIPSE Consortium, Rachael Stolzenberg-Solomon, Pablo Gejman, Qing Lan, Nathaniel Rothman, Laufey T Amundadottir, Maria Teresa Landi, Douglas F Levinson, Stephen J Chanock, Nilanjan Chatterjee
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006493 (2016)
Recent heritability analyses have indicated that genome-wide association studies (GWAS) have the potential to improve genetic risk prediction for complex diseases based on polygenic risk score (PRS), a simple modelling technique that can be implement
Externí odkaz:
https://doaj.org/article/a59b3243ed1d40f794cbb7048b649f62
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117230 (2015)
OBJECTIVES:Although type 2 diabetes mellitus is a known risk factor for pancreatic cancer, the existence of shared genetic susceptibility is largely unknown. We evaluated whether any reported genetic risk variants of either disease found by genome-wi
Externí odkaz:
https://doaj.org/article/82eb7ecea48649d0a86621a8e8baaa7f
Autor:
Hannah Arem, Kai Yu, Xiaoqin Xiong, Kristin Moy, Neal D Freedman, Susan T Mayne, Demetrius Albanes, Alan A Arslan, Melissa Austin, William R Bamlet, Laura Beane-Freeman, Paige Bracci, Federico Canzian, Michelle Cotterchio, Eric J Duell, Steve Gallinger, Graham G Giles, Michael Goggins, Phyllis J Goodman, Patricia Hartge, Manal Hassan, Kathy Helzlsouer, Brian Henderson, Elizabeth A Holly, Robert Hoover, Eric J Jacobs, Aruna Kamineni, Alison Klein, Eric Klein, Laurence N Kolonel, Donghui Li, Núria Malats, Satu Männistö, Marjorie L McCullough, Sara H Olson, Irene Orlow, Ulrike Peters, Gloria M Petersen, Miquel Porta, Gianluca Severi, Xiao-Ou Shu, Kala Visvanathan, Emily White, Herbert Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Geoffrey S Tobias, Dennis Maeder, Michelle Brotzman, Harvey Risch, Joshua N Sampson, Rachael Z Stolzenberg-Solomon
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117574 (2015)
Evidence on the association between vitamin D status and pancreatic cancer risk is inconsistent. This inconsistency may be partially attributable to variation in vitamin D regulating genes. We selected 11 vitamin D-related genes (GC, DHCR7, CYP2R1, V
Externí odkaz:
https://doaj.org/article/4780aef1d7f5435182461f1e11d75b6e
Autor:
Hannah Arem, Kai Yu, Xiaoqin Xiong, Kristin Moy, Neal D Freedman, Susan T Mayne, Demetrius Albanes, Laufey T Amundadottir, Alan A Arslan, Melissa Austin, William R Bamlet, Laura Beane-Freeman, Paige Bracci, Federico Canzian, Stephen J Chanock, Michelle Cotterchio, Eric J Duell, Steve Gallinger, Graham G Giles, Michael Goggins, Phyllis J Goodman, Patricia Hartge, Manal Hassan, Kathy Helzlsouer, Brian Henderson, Elizabeth A Holly, Robert Hoover, Eric J Jacobs, Aruna Kamineni, Alison Klein, Eric Klein, Laurence N Kolonel, Donghui Li, Núria Malats, Satu Männistö, Marjorie L McCullough, Sara H Olson, Irene Orlow, Ulrike Peters, Gloria M Petersen, Miquel Porta, Gianluca Severi, Xiao-Ou Shu, Stephen Van Den Eeden, Kala Visvanathan, Emily White, Herbert Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Geoffrey S Tobias, Dennis Maeder, Michelle Brotzman, Harvey Risch, Joshua N Sampson, Rachael Z Stolzenberg-Solomon
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129983 (2015)
Externí odkaz:
https://doaj.org/article/aa4f3f44a7a54110af0352048a79f630
Autor:
Lisa A Boardman, Ruth A Johnson, Kimberly B Viker, Kari A Hafner, Robert B Jenkins, Douglas L Riegert-Johnson, Thomas C Smyrk, Kristin Litzelman, Songwon Seo, Ronald E Gangnon, Corinne D Engelman, David N Rider, Russell J Vanderboom, Stephen N Thibodeau, Gloria M Petersen, Halcyon G Skinner
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80015 (2013)
IntroductionColorectal cancer (CRC) tumor DNA is characterized by chromosomal damage termed chromosomal instability (CIN) and excessively shortened telomeres. Up to 80% of CRC is microsatellite stable (MSS) and is historically considered to be chromo
Externí odkaz:
https://doaj.org/article/0cbf7004f69043d4a6e8c2961198119c
Autor:
Alison P Klein, Sara Lindström, Julie B Mendelsohn, Emily Steplowski, Alan A Arslan, H Bas Bueno-de-Mesquita, Charles S Fuchs, Steven Gallinger, Myron Gross, Kathy Helzlsouer, Elizabeth A Holly, Eric J Jacobs, Andrea Lacroix, Donghui Li, Margaret T Mandelson, Sara H Olson, Gloria M Petersen, Harvey A Risch, Rachael Z Stolzenberg-Solomon, Wei Zheng, Laufey Amundadottir, Demetrius Albanes, Naomi E Allen, William R Bamlet, Marie-Christine Boutron-Ruault, Julie E Buring, Paige M Bracci, Federico Canzian, Sandra Clipp, Michelle Cotterchio, Eric J Duell, Joanne Elena, J Michael Gaziano, Edward L Giovannucci, Michael Goggins, Göran Hallmans, Manal Hassan, Amy Hutchinson, David J Hunter, Charles Kooperberg, Robert C Kurtz, Simin Liu, Kim Overvad, Domenico Palli, Alpa V Patel, Kari G Rabe, Xiao-Ou Shu, Nadia Slimani, Geoffrey S Tobias, Dimitrios Trichopoulos, Stephen K Van Den Eeden, Paolo Vineis, Jarmo Virtamo, Jean Wactawski-Wende, Brian M Wolpin, Herbert Yu, Kai Yu, Anne Zeleniuch-Jacquotte, Stephen J Chanock, Robert N Hoover, Patricia Hartge, Peter Kraft
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72311 (2013)
We developed an absolute risk model to identify individuals in the general population at elevated risk of pancreatic cancer.Using data on 3,349 cases and 3,654 controls from the PanScan Consortium, we developed a relative risk model for men and women
Externí odkaz:
https://doaj.org/article/df004024296a457dbf8a9b710f783b2e
Leukocyte DNA methylation signature differentiates pancreatic cancer patients from healthy controls.
Autor:
Katrina S Pedersen, William R Bamlet, Ann L Oberg, Mariza de Andrade, Martha E Matsumoto, Hui Tang, Stephen N Thibodeau, Gloria M Petersen, Liang Wang
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18223 (2011)
Pancreatic adenocarcinoma (PaC) is one of most difficult tumors to treat. Much of this is attributed to the late diagnosis. To identify biomarkers for early detection, we examined DNA methylation differences in leukocyte DNA between PaC cases and con
Externí odkaz:
https://doaj.org/article/1a82d48ff64649d6bca7a525be720023