Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Gloria Lazzeri"'
Autor:
Roberto Pinelli, Michela Ferrucci, Francesca Biagioni, Caterina Berti, Violet Vakunseth Bumah, Carla Letizia Busceti, Stefano Puglisi-Allegra, Gloria Lazzeri, Alessandro Frati, Francesco Fornai
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1183 (2023)
The seminal role of autophagy during age-related macular degeneration (AMD) lies in the clearance of a number of reactive oxidative species that generate dysfunctional mitochondria. In fact, reactive oxygen species (ROS) in the retina generate misfol
Externí odkaz:
https://doaj.org/article/1b46e14bd65540d886664826fad720a6
Autor:
Paola Lenzi, Carla L. Busceti, Gloria Lazzeri, Rosangela Ferese, Francesca Biagioni, Alessandra Salvetti, Elena Pompili, Valerio De Franchis, Stefano Puglisi-Allegra, Alessandro Frati, Michela Ferrucci, Francesco Fornai
Publikováno v:
Cells, Vol 12, Iss 2, p 221 (2023)
Cells from glioblastoma multiforme (GBM) feature up-regulation of the mechanistic Target of Rapamycin (mTOR), which brings deleterious effects on malignancy and disease course. At the cellular level, up-regulation of mTOR affects a number of downstre
Externí odkaz:
https://doaj.org/article/684e5e724abc4c54991f33956bda756a
Autor:
Michela Ferrucci, Carla Letizia Busceti, Gloria Lazzeri, Francesca Biagioni, Stefano Puglisi-Allegra, Alessandro Frati, Paola Lenzi, Francesco Fornai
Publikováno v:
Molecules, Vol 27, Iss 16, p 5204 (2022)
The neurotoxins methamphetamine (METH) and 1-methyl-4-phenylpyridinium (MPP+) damage catecholamine neurons. Although sharing the same mechanism to enter within these neurons, METH neurotoxicity mostly depends on oxidative species, while MPP+ toxicity
Externí odkaz:
https://doaj.org/article/c0b8e66fa68f470883e06519eaed7972
Autor:
Federica Mastroiacovo, Francesca Biagioni, Paola Lenzi, Gloria Lazzeri, Michela Ferrucci, Stefano Puglisi-Allegra, Alessandro Frati, Ferdinando Nicoletti, Francesco Fornai
Publikováno v:
Molecules, Vol 27, Iss 10, p 3122 (2022)
The brain area which surrounds the frankly ischemic region is named the area penumbra. In this area, most cells are spared although their oxidative metabolism is impaired. area penumbra is routinely detected by immunostaining of a molecule named Heat
Externí odkaz:
https://doaj.org/article/b196171356bd4f60be5d7eabbc44c7ae
Autor:
Gianfranco Natale, Larisa Ryskalin, Gabriele Morucci, Gloria Lazzeri, Alessandro Frati, Francesco Fornai
Publikováno v:
Life, Vol 11, Iss 8, p 732 (2021)
The gastrointestinal (GI) tract is provided with a peculiar nervous network, known as the enteric nervous system (ENS), which is dedicated to the fine control of digestive functions. This forms a complex network, which includes several types of neuro
Externí odkaz:
https://doaj.org/article/e1f26986681844649b3499ee305341a2
Autor:
Larisa Ryskalin, Stefano Puglisi-Allegra, Gloria Lazzeri, Francesca Biagioni, Carla L. Busceti, Linda Balestrini, Andrea Fornasiero, Stefano Leone, Elena Pompili, Michela Ferrucci, Francesco Fornai
Publikováno v:
Molecules, Vol 26, Iss 9, p 2493 (2021)
Curcumin (CUR), a natural polyphenol extracted from rhizome of the Curcuma longa L, has received great attention for its multiple potential health benefits as well as disease prevention. For instance, CUR protects against toxic agents acting on the h
Externí odkaz:
https://doaj.org/article/ae8bd22c7d7741409056c50edfc3a041
Autor:
Fiona Limanaqi, Carla Letizia Busceti, Francesca Biagioni, Gloria Lazzeri, Maurizio Forte, Sonia Schiavon, Sebastiano Sciarretta, Giacomo Frati, Francesco Fornai
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1105 (2020)
The novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has generated the ongoing coronavirus disease-2019 (COVID-19) pandemic, still with an uncertain outcome. Besides pneumonia and acute lung injury (ALI) or acute r
Externí odkaz:
https://doaj.org/article/0f574df784474125a6197374fecc6b40
Autor:
Fiona Limanaqi, Francesca Biagioni, Federica Mastroiacovo, Maico Polzella, Gloria Lazzeri, Francesco Fornai
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 1022 (2020)
Wide experimental evidence has been provided in the last decade concerning the neuroprotective effects of phytochemicals in a variety of neurodegenerative disorders. Generally, the neuroprotective effects of bioactive compounds belonging to different
Externí odkaz:
https://doaj.org/article/11930bc97e9a4abaa14c3f1c7a2d75a4
Autor:
Larisa Ryskalin, Francesca Biagioni, Carla L. Busceti, Gloria Lazzeri, Alessandro Frati, Francesco Fornai
Publikováno v:
Molecules, Vol 25, Iss 20, p 4839 (2020)
The present review focuses on the multi-faceted effects of curcumin on the neurobiology glioblastoma multiforme (GBM), with a special emphasis on autophagy (ATG)-dependent molecular pathways activated by such a natural polyphenol. This is consistent
Externí odkaz:
https://doaj.org/article/c1ffafee135d4e89bfde00660f7af33b
Autor:
Paola Lenzi, Gloria Lazzeri, Francesca Biagioni, Carla Letizia Busceti, Stefano Gambardella, Alessandra Salvetti, Francesco Fornai
Publikováno v:
Frontiers in Neuroanatomy, Vol 10 (2016)
Protein clearing pathways named autophagy (ATG) and ubiquitin proteasome (UP) control homeostasis within eukaryotic cells, while their dysfunction produces neurodegeneration. These pathways are viewed as distinct biochemical cascades occurring within
Externí odkaz:
https://doaj.org/article/8c757ce7e57b401fb7083585dc5509ee