Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Gloria G. Chan"'
Autor:
Xia Liu, Jiaji G. Chen, Manit Munshi, Zachary R. Hunter, Lian Xu, Amanda Kofides, Nickolas Tsakmaklis, Maria G. Demos, Maria Luisa Guerrera, Gloria G. Chan, Cristina Jimenez, Christopher J. Patterson, Kirsten Meid, Andrew Keezer, Jorge J. Castillo, Steven P. Treon, Guang Yang
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 141-153 (2020)
Abstract: Hematopoietic cell kinase (HCK) is an SRC family member that is aberrantly upregulated in B-cell neoplasms dependent on MYD88-activating mutations and supports their growth and survival. We showed herein that activation of Toll-like recepto
Externí odkaz:
https://doaj.org/article/f0c549eb05534163bf4e7c11455f1321
Autor:
Joshua N. Gustine, Lian Xu, Nicholas Tsakmaklis, Maria G. Demos, Amanda Kofides, Jiaji G. Chen, Xia Liu, Manit Munshi, Maria Luisa Guerrera, Gloria G. Chan, Christopher J. Patterson, Andrew Keezer, Kirsten Meid, Toni Dubeau, Guang Yang, Zachary R. Hunter, Steven P. Treon, Jorge J. Castillo
Publikováno v:
Blood Advances, Vol 3, Iss 19, Pp 2800-2803 (2019)
Externí odkaz:
https://doaj.org/article/c0cacde5eb6e4167bd409e330e343bec
Autor:
Maria Luisa Guerrera, Nickolas Tsakmaklis, Lian Xu, Guang Yang, Maria Demos, Amanda Kofides, Gloria G. Chan, Robert J. Manning, Xia Liu, Jiaji G. Chen, Manit Munshi, Christopher J. Patterson, Jorge J. Castillo, Toni Dubeau, Joshua Gustine, Ruben D. Carrasco, Luca Arcaini, Marzia Varettoni, Mario Cazzola, Steven P. Treon, Zachary R. Hunter
Publikováno v:
Haematologica, Vol 103, Iss 9 (2018)
Externí odkaz:
https://doaj.org/article/2dd51763f66444f692f0788be558c7a4
Publikováno v:
Journal of Proteome Research. 16:4104-4112
Transthyretin (TTR), normally a plasma circulating protein, can become misfolded and aggregated, ultimately leading to extracellular deposition of amyloid fibrils usually targeted to heart or nerve tissues. Referred to as TTR-associated amyloidoses (
Publikováno v:
Journal of Proteome Research. 16:1659-1668
Transthyretin-associated forms of cardiac amyloidosis are fatal protein misfolding diseases that can be inherited (ATTRm) or acquired (ATTRwt). An accurate diagnosis of ATTR amyloidosis can be challenging as biopsy evidence, usually from the affected
Autor:
Gloria G. Chan, Marios Arvanitis, Frederick L. Ruberg, Daniel R. Jacobson, Lawreen H. Connors, John L. Berk
Publikováno v:
Amyloid. 24:253-255
A valine to isoleucine amino acid substitution at position 122 (V122I or p.V142I) of the transthyretin (TTR) gene induces misfolding of this hepatic transport protein, conferring a clinical phenoty...
Autor:
Jiaji G, Chen, Xia, Liu, Manit, Munshi, Lian, Xu, Nicholas, Tsakmaklis, Maria G, Demos, Amanda, Kofides, Maria Luisa, Guerrera, Gloria G, Chan, Christopher J, Patterson, Kirsten, Meid, Joshua, Gustine, Toni, Dubeau, Patricia, Severns, Jorge J, Castillo, Zachary R, Hunter, Jinhua, Wang, Sara J, Buhrlage, Nathanael S, Gray, Steven P, Treon, Guang, Yang
Publikováno v:
Blood. 131(18)
Acquired ibrutinib resistance due to BTK
Autor:
Frederick L. Ruberg, Paula Beardsley, Denise Fine, Clarissa M. Koch, Steven Simon, Marios Arvanitis, John L. Berk, Lawreen H. Connors, Gloria G. Chan, Michael P. LaValley, Daniel R. Jacobson
Publikováno v:
Amyloid. 24:120-121
Transthyretin amyloid cardiomyopathy (ATTR cam) is likely an under-recognized cause of heart failure (HF) in the elderly [1], owing to misattribution of clinical features to other common co-morbidi...
Autor:
Jacquelyn L. Sikora, Gloria G. Chan, David C. Seldin, Tatiana Prokaeva, Mark W. Logue, Clinton T. Baldwin, Brian Spencer, Lawreen H. Connors
Wild-type transthyretin amyloidosis (ATTRwt), typically diagnosed as congestive heart failure in elderly Caucasian men, features myocardial amyloid deposits of wild-type plasma protein transthyretin (TTR). ATTRwt is sporadic, its pathogenesis is poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227c008980d6db0613083dd51856ea90
https://europepmc.org/articles/PMC4282974/
https://europepmc.org/articles/PMC4282974/
Autor:
John L. Berk, Gloria G. Chan, Celia Torres-Arancivia, Lawreen H. Connors, Marios Arvanitis, Daniel R. Jacobson, Frederick L. Ruberg, Clarissa M. Koch, Michael P. LaValley
Publikováno v:
JAMA Cardiology. 2:305
Importance Transthyretin cardiac amyloidosis (ATTR) is an underrecognized cause of heart failure (HF) in older individuals, owing in part to difficulty in diagnosis. ATTR can result from substitution of valine for isoleucine at codon 122 of the trans