Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gloria C. Preza"'
Autor:
Gloria C. Preza, Tomas Ganz, Johannes W. A. van Dijk, Elizabeta Nemeth, David J. Craik, Chia Chia Tan, Eileen Fung, Richard J. Clark
Publikováno v:
Peptide Science. 100:519-526
The peptide hormone hepcidin is a key regulator of iron homeostasis in vertebrates. Hepcidin acts by binding to ferroportin, the sole known iron exporter, causing it to be internalized and thus trapping iron within the cell. Dysregulation of hepcidin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85ea1428515a6e2e217a690b47ca87a
https://doi.org/10.1002/bip.22350
https://doi.org/10.1002/bip.22350
Autor:
Gloria C. Preza, Piotr Ruchala, Emilio Ramos, Léon Kautz, Tomas Ganz, Julia B. Goodnough, Elizabeta Nemeth
Publikováno v:
Blood. 120:3829-3836
The deficiency of hepcidin, the hormone that controls iron absorption and its tissue distribution, is the cause of iron overload in nearly all forms of hereditary hemochromatosis and in untransfused iron-loading anemias. In a recent study, we reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d10a55a9b12b99fae2d84058f4236f
https://doi.org/10.1182/blood-2012-07-440743
https://doi.org/10.1182/blood-2012-07-440743
Publikováno v:
Blood. 107:328-333
Hepcidin is the principal iron-regulatory hormone. It acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. The bioactive 25 amino acid (aa) peptide has a hairpin struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03866abc3052152a8c94a7c2a5cd3fe6
https://doi.org/10.1182/blood-2005-05-2049
https://doi.org/10.1182/blood-2005-05-2049
Autor:
Gill Diamond, Sujata Yavagal, Sheila J. Greene, Edith Porter, Omar Murillo, Gloria C. Preza, Heriberto Lima, Marcia E. Klein-Patel, Huixia Yang, Laily Mahoozi, Sunita Gulati, Peter A. Rice, Tomas Ganz, Alison J. Quayle
Publikováno v:
Infection and Immunity. 73:4823-4833
Defensins are key participants in mucosal innate defense. The varied antimicrobial activity and differential distribution of defensins at mucosal sites indicate that peptide repertoires are tailored to site-specific innate defense requirements. Nonet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c279f298bcd3b9a894fa91912e5c8bd
https://doi.org/10.1128/iai.73.8.4823-4833.2005
https://doi.org/10.1128/iai.73.8.4823-4833.2005
Publikováno v:
PloS one, vol 10, iss 4
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0122723 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0122723 (2015)
Mucosal tissues are critical immune effector sites containing complex populations of leukocytes in a tissue microenvironment that remains incompletely understood. We identify and quantify in human distal colorectal tissue absolute mucosal CD3+ lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d320c75e0cc243efd81a5f967a765f4
https://escholarship.org/uc/item/73s6w5wz
https://escholarship.org/uc/item/73s6w5wz
Autor:
Gloria C. Preza, Peter A. Anton, Julie Elliott, Otto O. Yang, Karen Tanner, Maria Teresa Ochoa
Publikováno v:
AIDS research and human retroviruses, vol 30, iss 3
A common route for HIV-1 infection is sexual transmission across colorectal mucosa, which is thought to be 10-2,000 times more vulnerable to infection than that of the female genital tract. Mucosal surfaces are the first line of defense against many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c290b49d33ae2f49807cd1b96b85a95
https://escholarship.org/uc/item/3s15w12p
https://escholarship.org/uc/item/3s15w12p
Autor:
Gloria C. Preza, Bo Qiao, Rogelio Pinon, Piotr Ruchala, Tomas Ganz, Shantanu Sharma, Alan J. Waring, Michael A. Peralta, Emilio Ramos, Elizabeta Nemeth
Iron overload is the hallmark of hereditary hemochromatosis and a complication of iron-loading anemias such as β-thalassemia. Treatment can be burdensome and have significant side effects, and new therapeutic options are needed. Iron overload in her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84c5aac7c12634fadc09c7335c86bda
https://europepmc.org/articles/PMC3225996/
https://europepmc.org/articles/PMC3225996/
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4609721d770828310bb7330931527f93
https://doi.org/10.1096/fasebj.25.1_supplement.1119.3
https://doi.org/10.1096/fasebj.25.1_supplement.1119.3
Autor:
Elizabeta Nemeth, Tomas Ganz, David J. Craik, Chia Chia Tan, Richard J. Clark, Gloria C. Preza
The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism and involved in pathological regulation of iron in response to infection, inflammation, hypoxia and anaemia. It acts by binding to the iron exporter ferroportin, causing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbb84f3ceafec00e6fa1e1eb88e7efc
https://europepmc.org/articles/PMC3073735/
https://europepmc.org/articles/PMC3073735/
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe78fddbb08c1e6355f14db0524acf13
https://doi.org/10.1096/fasebj.24.1_supplement.1011.1
https://doi.org/10.1096/fasebj.24.1_supplement.1011.1