Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Gloria C, Chiang"'
Autor:
Yihao Guo, Liangdong Zhou, Yi Li, Gloria C. Chiang, Tao Liu, Huijuan Chen, Weiyuan Huang, Mony J. de Leon, Yi Wang, Feng Chen
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Quantitative transport mapping (QTM) of blood velocity, based on the transport equation has been demonstrated higher accuracy and sensitivity of perfusion quantification than the traditional Kety’s method-based cerebral blood fl
Externí odkaz:
https://doaj.org/article/14c5fbddc8344df2b21dd365eb46ff4c
Autor:
Neel H. Mehta, Xiuyuan Wang, Samantha A. Keil, Ke Xi, Liangdong Zhou, Kevin Lee, Wanbin Tan, Edward Spector, Amirhossein Goldan, James Kelly, Nicolas A. Karakatsanis, P. David Mozley, Sadek Nehmeh, J. Levi Chazen, Simon Morin, John Babich, Jana Ivanidze, Silky Pahlajani, Emily B. Tanzi, Leslie Saint-Louis, Tracy Butler, Kewei Chen, Henry Rusinek, Roxana O. Carare, Yi Li, Gloria C. Chiang, Mony J. de Leon
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background Reduced clearance of cerebrospinal fluid (CSF) has been suggested as a pathological feature of Alzheimer’s disease (AD). With extensive documentation in non-human mammals and contradictory human neuroimaging data it remains unkn
Externí odkaz:
https://doaj.org/article/038120f6c203440699043248097157ee
Autor:
Neel H. Mehta, Liangdong Zhou, Yi Li, Laura Beth McIntire, Anna Nordvig, Tracy Butler, Mony de Leon, Gloria C. Chiang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Neuroinflammation is believed to be a key process in Alzheimer’s disease (AD) pathogenesis. Recently, the neutrophil-to-lymphocyte (NLR) and lymphocyte-to-monocyte ratios (LMR) have been proposed to be useful peripheral markers of inflamma
Externí odkaz:
https://doaj.org/article/2f2e267ff99946808c84242a0cab048c
Autor:
Liangdong Zhou, Yi Li, Elizabeth M. Sweeney, Xiuyuan H. Wang, Amy Kuceyeski, Gloria C. Chiang, Jana Ivanidze, Yi Wang, Susan A. Gauthier, Mony J. de Leon, Thanh D. Nguyen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Background and purposeOur objective was to apply multi-compartment T2 relaxometry in cognitively normal individuals aged 20–80 years to study the effect of aging on the parenchymal CSF fraction (CSFF), a potential measure of the subvoxel CSF space.
Externí odkaz:
https://doaj.org/article/0bb2151f3dfb410aad3fcac1a34e9636
Autor:
Anna S. Nordvig, Mangala Rajan, Jennifer D. Lau, Justin R. Kingery, Meem Mahmud, Gloria C. Chiang, Mony J. De Leon, Parag Goyal
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ImportanceThe U.S. government has named post-acute sequelae of COVID-19 (longCOVID) as influential on disability rates. We previously showed that COVID-19 carries a medical/functional burden at 1 year, and that age and other risk factors of severe CO
Externí odkaz:
https://doaj.org/article/b695dbd9b3924920a0b9a06d1ead1546
Autor:
Seyed Hani Hojjati, Tracy A. Butler, Gloria C. Chiang, Christian Habeck, Arindam RoyChoudhury, Farnia Feiz, Jacob Shteingart, Siddharth Nayak, Sindy Ozoria, Antonio Fernández, Yaakov Stern, José A. Luchsinger, Davangere P. Devanand, Qolamreza R. Razlighi
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103409- (2023)
Alzheimer's disease (AD) is defined by the presence of Amyloid-β (Aβ), tau, and neurodegeneration (ATN framework) in the human cerebral cortex. Yet, prior studies have suggested that Aβ deposition can be associated with both cortical thinning and
Externí odkaz:
https://doaj.org/article/c4a6d57e4e1f429aba4b5f38b94575c2
Autor:
Neel H. Mehta, Richard A. Suss, Jonathan P. Dyke, Neil D. Theise, Gloria C. Chiang, Sara Strauss, Leslie Saint-Louis, Yi Li, Silky Pahlajani, Vivek Babaria, Lidia Glodzik, Roxana O. Carare, Mony J. de Leon
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105776- (2022)
Cerebrospinal fluid (CSF), predominantly produced in the ventricles and circulating throughout the brain and spinal cord, is a key protective mechanism of the central nervous system (CNS). Physical cushioning, nutrient delivery, metabolic waste, incl
Externí odkaz:
https://doaj.org/article/0f599b471db34d7ab3b78b2b0ab98636
Autor:
Neel H. Mehta, Jonah Sherbansky, Angela R. Kamer, Roxana O. Carare, Tracy Butler, Henry Rusinek, Gloria C. Chiang, Yi Li, Sara Strauss, L. A. Saint-Louis, Neil D. Theise, Richard A. Suss, Kaj Blennow, Michael Kaplitt, Mony J. de Leon
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
The human brain functions at the center of a network of systems aimed at providing a structural and immunological layer of protection. The cerebrospinal fluid (CSF) maintains a physiological homeostasis that is of paramount importance to proper neuro
Externí odkaz:
https://doaj.org/article/66f26e66bfc045c3b1356ec2725aaaf4
Autor:
Matthew, Spano, Michelle, Roytman, Mariam, Aboian, Babak, Saboury, Ana, Franceschi, Gloria C, Chiang
Publikováno v:
PET clinics. 18(1)
Alzheimer disease (AD) is the most common cause of dementia, accounting for 50% to 60% of cases and affecting nearly 6 million people in the United States. Definitive diagnosis requires either antemortem brain biopsy or postmortem autopsy. However, c
Autor:
Matthew Spano, Michelle Roytman, Mariam Aboian, Babak Saboury, Ana M. Franceschi, Gloria C. Chiang
Publikováno v:
PET Clinics. 18:103-113