Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Gloria Bonuccelli"'
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166500 (2016)
Osteosarcoma (OS) is an aggressive bone malignancy with a high relapse rate despite combined treatment with surgery and multiagent chemotherapy. As for other cancers, OS-associated microenvironment may contribute to tumor initiation, growth, and meta
Externí odkaz:
https://doaj.org/article/2cbde66cbd784f00a141841910808944
Autor:
Manuela Salerno, Sofia Avnet, Gloria Bonuccelli, Shigekuni Hosogi, Donatella Granchi, Nicola Baldini
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110340 (2014)
Rhabdomyosarcoma is the most frequent soft tissue sarcoma in children and adolescents, with a high rate of relapse that dramatically affects the clinical outcome. Multiagent chemotherapy, in combination with surgery and/or radiation therapy, is the t
Externí odkaz:
https://doaj.org/article/d9c6cbb2033145679140ff3a9a215ce9
Autor:
Karla P C Araujo, Gloria Bonuccelli, Caio N Duarte, Thais P Gaiad, Dayson F Moreira, David Feder, José E Belizario, Maria A Miglino, Michael P Lisanti, Carlos E Ambrosio
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61367 (2013)
Golden retriever muscular dystrophy (GRMD) is a genetic myopathy corresponding to Duchenne muscular dystrophy (DMD) in humans. Muscle atrophy is known to be associated with degradation of the dystrophin-glycoprotein complex (DGC) via the ubiquitin-pr
Externí odkaz:
https://doaj.org/article/733549b881904fa3852b64c77fb202e8
Autor:
Franco Capozza, Michael P. Lisanti, Federica Sotgia, Richard G. Pestell, Andrew E. Aplin, Kristin M. Daumer, Janet N. Milliman, Gloria Bonuccelli, Diana Whitaker-Menezes, Casey Trimmer
Supplementary Figure Legends 1-2 from CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44749483eeb061e71b98a331578826a8
https://doi.org/10.1158/0008-5472.22385268
https://doi.org/10.1158/0008-5472.22385268
Autor:
Franco Capozza, Michael P. Lisanti, Federica Sotgia, Richard G. Pestell, Andrew E. Aplin, Kristin M. Daumer, Janet N. Milliman, Gloria Bonuccelli, Diana Whitaker-Menezes, Casey Trimmer
Supplementary Methods from CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f0f787bac3d54f67a556db2eceabb7
https://doi.org/10.1158/0008-5472.22385265
https://doi.org/10.1158/0008-5472.22385265
Autor:
Franco Capozza, Michael P. Lisanti, Federica Sotgia, Richard G. Pestell, Andrew E. Aplin, Kristin M. Daumer, Janet N. Milliman, Gloria Bonuccelli, Diana Whitaker-Menezes, Casey Trimmer
Caveolin-1 (CAV1) is the main structural component of caveolae, which are plasma membrane invaginations that participate in vesicular trafficking and signal transduction events. Although evidence describing the function of CAV1 in several cancer type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b254b92a5057f175bf775a4db2e4634
https://doi.org/10.1158/0008-5472.c.6501171.v1
https://doi.org/10.1158/0008-5472.c.6501171.v1
Autor:
Franco Capozza, Michael P. Lisanti, Federica Sotgia, Richard G. Pestell, Andrew E. Aplin, Kristin M. Daumer, Janet N. Milliman, Gloria Bonuccelli, Diana Whitaker-Menezes, Casey Trimmer
Supplementary Tables 1-2, Figures 1-2 from CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f2e3d39fcb014e2041cc2327e75d1f
https://doi.org/10.1158/0008-5472.22385262.v1
https://doi.org/10.1158/0008-5472.22385262.v1
Autor:
Federica Sotgia, Marco Fiorillo, Ernestina Marianna De Francesco, Béla Ózsvári, Gloria Bonuccelli, Michael P. Lisanti
Publikováno v:
Cell Cycle
Here, we wish to propose a new systematic approach to cancer therapy, based on the targeting of mitochondrial metabolism, especially in cancer stem cells (CSCs). In the future, we envision that anti-mitochondrial therapy would ultimately be practiced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83463efdaa8eb1ab2c0212d042f49129
https://doi.org/10.1080/15384101.2018.1515551
https://doi.org/10.1080/15384101.2018.1515551
Publikováno v:
Oncotarget
Peiris-Pagès, M, Bonuccelli, G, Sotgia, F & Lisanti, M P 2018, ' Mitochondrial fission as a driver of stemness in tumor cells : mDIVI1 inhibits mitochondrial function, cell migration and cancer stem cell (CSC) signalling ', Oncotarget, vol. 9, no. 17, pp. 13254-13275 . https://doi.org/10.18632/oncotarget.24285
Peiris-Pagès, M, Bonuccelli, G, Sotgia, F & Lisanti, M P 2018, ' Mitochondrial fission as a driver of stemness in tumor cells : mDIVI1 inhibits mitochondrial function, cell migration and cancer stem cell (CSC) signalling ', Oncotarget, vol. 9, no. 17, pp. 13254-13275 . https://doi.org/10.18632/oncotarget.24285
Mitochondria are dynamic organelles frequently undergoing fission and fusion events to maintain their integrity, bioenergetics and spatial distribution, which is fundamental to the processes of cell survival. Disruption in mitochondrial dynamics play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9292d225c68920986b39f1e05cf7c2
https://doi.org/10.18632/oncotarget.24285
https://doi.org/10.18632/oncotarget.24285
Autor:
Marcello Maggiolini, Gloria Bonuccelli, Ernestina Marianna De Francesco, Michael P. Lisanti, Federica Sotgia
Publikováno v:
Oncotarget
Here, we developed a new synthetic lethal strategy for further optimizing the eradication of cancer stem cells (CSCs). Briefly, we show that chronic treatment with the FDA-approved antibiotic Doxycycline effectively reduces cellular respiration, by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ab4acf8f9358f610850b7b80905b43
http://europepmc.org/articles/PMC5620172
http://europepmc.org/articles/PMC5620172