Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Gloria Allocca"'
Autor:
Amanda J. Eakin, Tamara Mc Erlain, Aileen Burke, Amy Eaton, Nuala Tipping, Gloria Allocca, Cristina M. Branco
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Anthracycline-based chemotherapy is a common treatment for cancer patients. Because it is delivered intravenously, endothelial cells are exposed first and to the highest concentrations, prior to diffusion to target cells. Not surprisingly, vascular d
Externí odkaz:
https://doaj.org/article/0d196414977643e4b2debd8462ac4fac
Autor:
Gloria Allocca, Russell Hughes, Ning Wang, Hannah K Brown, Penelope D Ottewell, Nicola J Brown, Ingunn Holen
Publikováno v:
Journal of Bone Oncology, Vol 17, Iss , Pp - (2019)
Background: Bone metastasis is one of the most common complications of advanced breast cancer. During dissemination to bone, breast cancer cells locate in a putative ‘metastatic niche’, a microenvironment that regulates the colonisation, maintena
Externí odkaz:
https://doaj.org/article/12c2aea1c17749b38ad1953739c04483
Autor:
Hannah K. Brown, Gloria Allocca, Penelope D. Ottewell, Ning Wang, Nicola J. Brown, Peter I. Croucher, Colby L. Eaton, Ingunn Holen
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2920 (2018)
Breast cancer cells colonize the skeleton by homing to specific niches, but the involvement of osteoblasts in tumour cell seeding, colonization, and progression is unknown. We used an in vivo model to determine how increasing the number of cells of t
Externí odkaz:
https://doaj.org/article/4bceb25f440c483e963a067ebf778dd8
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Summary of the effects of IL-1B on breast cancer progression to metastasis and growth in the bone microenvironment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c966886aa3515add73124f35ba96fdd4
https://doi.org/10.1158/1078-0432.22472744.v1
https://doi.org/10.1158/1078-0432.22472744.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Suppression of IL-1 signalling affects bone integrity and vasculature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c325261461851db8ab242f40b164f0c7
https://doi.org/10.1158/1078-0432.22472750.v1
https://doi.org/10.1158/1078-0432.22472750.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44d71f01e6bbe78530a36fc9eede0dc
https://doi.org/10.1158/1078-0432.22472741.v1
https://doi.org/10.1158/1078-0432.22472741.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Effects of IL-1B on osteoclast and osteoblast activity in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b007b54acb30669ee466909235f57
https://doi.org/10.1158/1078-0432.22472747.v1
https://doi.org/10.1158/1078-0432.22472747.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Incubation with high concentrations of exogenous IL-1B modestly increases tumour cell migration and invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba561472369534842ef8e89064113d
https://doi.org/10.1158/1078-0432.22472756.v1
https://doi.org/10.1158/1078-0432.22472756.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
In vivo model of spontaneous human breast cancer metastasis to human bone implants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6e4ee90c1febd67029eac311f790e5
https://doi.org/10.1158/1078-0432.22472765.v1
https://doi.org/10.1158/1078-0432.22472765.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Purpose:Breast cancer bone metastases are incurable, highlighting the need for new therapeutic targets. After colonizing bone, breast cancer cells remain dormant, until signals from the microenvironment stimulate outgrowth into overt metastases. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1129d3ad9037fd9bc83853742bf10c0d
https://doi.org/10.1158/1078-0432.c.6528317.v1
https://doi.org/10.1158/1078-0432.c.6528317.v1