Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gloria Agatic"'
Autor:
Paola De Benedictis, Andrea Minola, Elena Rota Nodari, Roberta Aiello, Barbara Zecchin, Angela Salomoni, Mathilde Foglierini, Gloria Agatic, Fabrizia Vanzetta, Rachel Lavenir, Anthony Lepelletier, Emma Bentley, Robin Weiss, Giovanni Cattoli, Ilaria Capua, Federica Sallusto, Edward Wright, Antonio Lanzavecchia, Hervé Bourhy, Davide Corti
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 4, Pp 407-421 (2016)
Abstract Currently available rabies post‐exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the h
Externí odkaz:
https://doaj.org/article/e80ee3d7220543d9872041b2b9068ffa
Autor:
Sophie B. Morgan, Barbara Holzer, Johanneke D. Hemmink, Francisco J. Salguero, John C. Schwartz, Gloria Agatic, Elisabetta Cameroni, Barbara Guarino, Emily Porter, Pramila Rijal, Alain Townsend, Bryan Charleston, Davide Corti, Elma Tchilian
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza virus infection is a significant global health threat. Because of the lack of cross-protective universal vaccines, short time window during which antivirals are effective and drug resistance, new therapeutic anti-influenza strategies are re
Externí odkaz:
https://doaj.org/article/1b716aab169c40a1b6838adbf3240115
Autor:
Jennifer D Watkins, Nagadenahalli B Siddappa, Samir K Lakhashe, Michael Humbert, Anton Sholukh, Girish Hemashettar, Yin Ling Wong, John K Yoon, Wendy Wang, Francis J Novembre, Francois Villinger, Chris Ibegbu, Kalpana Patel, Davide Corti, Gloria Agatic, Fabrizia Vanzetta, Siro Bianchi, Jonathan L Heeney, Federica Sallusto, Antonio Lanzavecchia, Ruth M Ruprecht
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18207 (2011)
Neutralizing antibodies have been shown to protect macaques against SHIV challenge. However, genetically diverse HIV-1 clades have evolved, and a key question left unanswered is whether neutralizing antibodies can confer cross-clade protection in viv
Externí odkaz:
https://doaj.org/article/18a1fa172f0a46cfb860a5bf3ee5b5cf
Autor:
Charles Sabin, Davide Corti, Victor Buzon, Mike S Seaman, David Lutje Hulsik, Andreas Hinz, Fabrizia Vanzetta, Gloria Agatic, Chiara Silacci, Lara Mainetti, Gabriella Scarlatti, Federica Sallusto, Robin Weiss, Antonio Lanzavecchia, Winfried Weissenhorn
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001195 (2010)
The human monoclonal antibody (mAb) HK20 neutralizes a broad spectrum of primary HIV-1 isolates by targeting the highly conserved heptad repeat 1 (HR1) of gp41, which is transiently exposed during HIV-1 entry. Here we present the crystal structure of
Externí odkaz:
https://doaj.org/article/4113aefed7d44746bb51fd1042013b95
Autor:
Costanza Casiraghi, Antonio Lanzavecchia, Markus Arnoldini, Tom Völler, Andrea Minola, Albulena Toska, Emma Slack, Alma Dal Co, Davide Corti, Sonia Barbieri, Gloria Agatic, Médéric Diard, Erik Bakkeren, Roland R. Regoes, Claude Loverdo, Douglas R. Brumley, Wolf-Dietrich Hardt, Roman Stocker, Mikael E. Sellin, Boas Felmy, Blanca Fernandez-Rodriguez, Florence Bansept, Luca Piccoli, Kathrin Moor, Sandra Y. Wotzka
Publikováno v:
Nature
Vaccine-induced high-avidity IgA can protect against bacterial enteropathogens by directly neutralizing virulence factors or by poorly defined mechanisms that physically impede bacterial interactions with the gut tissues ('immune exclusion'). IgA-med
Autor:
Masaru Kanekiyo, Ryan P. Staupe, Julie E. Ledgerwood, Elisabetta Cameroni, Chiara Silacci, Aurélie Ploquin, Jean-jacques Muyembe-Tamfun, John C. Trefry, Davide Corti, John Misasi, Gloria Agatic, Wei Shi, John R. Mascola, Laurent Perez, Sabue Mulangu, Neville K. Kisalu, Antonio Lanzavecchia, Ingelise J. Gordon, Emily A. Thompson, Barney S. Graham, Suzanne E. Wollen, Blanca Fernandez-Rodriguez, Federica Sallusto, Fabrizia Vanzetta, Nicole A. Doria-Rose, Misook Choe, Michael Bailey, Alberto Cagigi, Nancy J. Sullivan, Daphne A. Stanley, Hadar Marcus
Publikováno v:
Science. 351:1339-1342
Antibodies block Ebola virus entry The recent Ebola virus outbreak in West Africa illustrates the need for both an effective vaccine and therapies to treat infected individuals. Corti et al. isolated two monoclonal antibodies from a survivor of the 1
Autor:
Barbara Guarino, Ursula Neu, Philip A. Walker, Patrick J. Collins, Frances J. Palmer-Hill, Josephine M. McAuliffe, Fabrizia Vanzetta, JoAnn Suzich, Anna De Marco, Stephen R. Martin, Roksana W. Ogrodowicz, Leslie Wachter-Rosati, Qing Zhu, Steven J. Gamblin, Gloria Agatic, Chiara Silacci, Andy Q. Yuan, Nicole L. Kallewaard, Debora Pinna, Mathilde Foglierini, Alexander Fruehwirth, Federica Sallusto, John J. Skehel, Matthias K. Vorlaender, Antonio Lanzavecchia, Ebony Benjamin, Davide Corti, Siro Bianchi, Blanca Fernandez-Rodriguez
Publikováno v:
Cell
Cell, 166 (3)
Cell, 166 (3)
Summary Influenza virus remains a threat because of its ability to evade vaccine-induced immune responses due to antigenic drift. Here, we describe the isolation, evolution, and structure of a broad-spectrum human monoclonal antibody (mAb), MEDI8852,
Autor:
Pramila Rijal, Johanneke D. Hemmink, Francisco J. Salguero, Elisabetta Cameroni, Barbara Holzer, Gloria Agatic, Elma Tchilian, Sophie B. Morgan, Emily Porter, Alain Townsend, David Corti, Bryan Charleston, Barbaro Guarino, John C. Schwartz
Publikováno v:
Morgan, S B, Holzer, B, Hemmink, J D, Salguero, F J, Schwartz, J C, Agatic, G, Cameroni, E, Guarino, B, Porter, E, Rijal, P, Townsend, A, Charleston, B, Corti, D & Tchilian, E 2018, ' Therapeutic Administration of Broadly Neutralizing FI6 Antibody Reveals Lack of Interaction Between Human IgG1 and Pig Fc Receptors ', Frontiers in Immunology, vol. 9, no. APR, 865 . https://doi.org/10.3389/fimmu.2018.00865
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Morgan, S B, Holzer, B, Hemmink, J, Salguero, F J, Schwartz, J C, Agatic, G, Cameroni, E, Guarino, B, Porter, E, Rijal, P, Townsend, A, Charleston, B, Corti, D & Tchilian, E 2018, ' Therapeutic administration of broadly neutralizing FI6 antibody reveals lack of interaction between human IgG1 and pig Fc receptors ', Frontiers in Immunology, vol. 9, 865 . https://doi.org/10.3389/fimmu.2018.00865
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Morgan, S B, Holzer, B, Hemmink, J, Salguero, F J, Schwartz, J C, Agatic, G, Cameroni, E, Guarino, B, Porter, E, Rijal, P, Townsend, A, Charleston, B, Corti, D & Tchilian, E 2018, ' Therapeutic administration of broadly neutralizing FI6 antibody reveals lack of interaction between human IgG1 and pig Fc receptors ', Frontiers in Immunology, vol. 9, 865 . https://doi.org/10.3389/fimmu.2018.00865
Influenza virus infection is a significant global health threat. Because of the lack of cross protective universal vaccines, short time window during which antivirals are effective and drug resistance, new therapeutic anti-influenza strategies are re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058617765b4a9278a6795bc13f3431b9
https://research-information.bris.ac.uk/en/publications/5e169453-1095-44a7-af23-7323b09eff9e
https://research-information.bris.ac.uk/en/publications/5e169453-1095-44a7-af23-7323b09eff9e
Autor:
Davide Corti, Luca Varani, Ralph S. Baric, Christopher J. Langrish, Nicholas A Barrett, Luca Simonelli, Maria Zambon, Mathilde Foglierini, Craig Fett, Sudhakar Agnihothram, Jincun Zhao, Federica Sallusto, Mattia Pedotti, Blanca Fernandez-Rodriguez, Antonio Lanzavecchia, Robin Gopal, Stanley Perlman, Fabrizia Vanzetta, Gloria Agatic
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels. There is no licensed vaccine or antiviral for MERS, therefore new p
Autor:
Robin A. Weiss, Donald N. Forthal, Jennifer D. Watkins, Antonio Lanzavecchia, Ruth M. Ruprecht, Samir K. Lakhashe, Barbara C. Bachler, Mingkui Zhou, Girish Hemashettar, Francois Villinger, Anton M Sholukh, Sandeep Gupta, Davide Corti, Swati Thorat, Quentin J. Sattentau, Gloria Agatic, Jonathan L. Heeney, Hemant K. Vyas
Publikováno v:
Vaccine, vol 33, iss 17
Although IgA is the most abundantly produced immunoglobulin in humans, its role in preventing HIV-1 acquisition, which occurs mostly via mucosal routes, remains unclear. In our passive mucosal immunizations of rhesus macaques (RMs), the anti-HIV-1 ne