Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Gloria A Benavides"'
Autor:
Diptiman Chanda, Mohammad Rehan, Samuel R Smith, Kevin G Dsouza, Yong Wang, Karen Bernard, Deepali Kurundkar, Vinayak Memula, Kyoko Kojima, James A Mobley, Gloria A Benavides, Victor Darley-Usmar, Young-iL Kim, Jaroslaw W Zmijewski, Jessy S Deshane, Stijn De Langhe, Victor J Thannickal
Publikováno v:
eLife, Vol 10 (2021)
Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the capacity to form t
Externí odkaz:
https://doaj.org/article/ef49c5e79b324a57988570b54d4ab9ff
Autor:
Saranya Ravi, Balu Chacko, Hirotaka Sawada, Philip A Kramer, Michelle S Johnson, Gloria A Benavides, Valerie O'Donnell, Marisa B Marques, Victor M Darley-Usmar
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123597 (2015)
Platelet thrombus formation includes several integrated processes involving aggregation, secretion of granules, release of arachidonic acid and clot retraction, but it is not clear which metabolic fuels are required to support these events. We hypoth
Externí odkaz:
https://doaj.org/article/ab466e185cc64b3b8f68f2bb25048a1e
Autor:
Mariame S. Kane, Gloria A. Benavides, Edie Osuma, Michelle S. Johnson, Helen E. Collins, Yecheng He, David Westbrook, Silvio H. Litovsky, Kasturi Mitra, John C. Chatham, Victor Darley-Usmar, Martin E. Young, Jianhua Zhang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Mitochondria morphology and function, and their quality control by mitophagy, are essential for heart function. We investigated whether these are influenced by time of the day (TOD), sex, and fed or fasting status, using transmission electro
Externí odkaz:
https://doaj.org/article/404d2c5db08241938901383fabf3f138
Autor:
Xiaosen Ouyang, Willayat Y. Wani, Gloria A. Benavides, Matthew J. Redmann, Hai Vo, Thomas van Groen, Victor M. Darley-Usmar, Jianhua Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4172-4184 (2023)
The lysosome is responsible for protein and organelle degradation and homeostasis and the cathepsins play a key role in maintaining protein quality control. Cathepsin D (CTSD), is one such lysosomal protease, which when deficient in humans lead to ne
Externí odkaz:
https://doaj.org/article/2ede50a0f6d7409a92eab27f601812d4
Autor:
Chae‐Myeong Ha, Sayan Bakshi, Manoja K. Brahma, Luke A. Potter, Samuel F. Chang, Zhihuan Sun, Gloria A. Benavides, Lihao He, Prachi Umbarkar, Luyun Zou, Samuel Curfman, Sini Sunny, Andrew J. Paterson, Namakkal‐Soorappan Rajasekaran, Jarrod W. Barnes, Jianhua Zhang, Hind Lal, Min Xie, Victor M. Darley‐Usmar, John C. Chatham, Adam R. Wende
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 19 (2023)
Background Lifestyle and metabolic diseases influence the severity and pathogenesis of cardiovascular disease through numerous mechanisms, including regulation via posttranslational modifications. A specific posttranslational modification, the additi
Externí odkaz:
https://doaj.org/article/be156b0fab8e4ad2aa747f5829ccfd51
Autor:
Xiaosen Ouyang, Sayan Bakshi, Gloria A. Benavides, Zhihuan Sun, Gerardo Hernandez‐Moreno, Helen E. Collins, Mariame S. Kane, Silvio Litovsky, Martin E. Young, John C. Chatham, Victor Darley‐Usmar, Adam R. Wende, Jianhua Zhang
Publikováno v:
Physiological Reports, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract Autophagy is important for protein and organelle quality control. Growing evidence demonstrates that autophagy is tightly controlled by transcriptional mechanisms, including repression by zinc finger containing KRAB and SCAN domains 3 (ZKSCA
Externí odkaz:
https://doaj.org/article/43138afb22a2441aa72b96c9dcaa2f7c
Autor:
Dominique C. Hinshaw, Gloria A. Benavides, Brandon J. Metge, Courtney A. Swain, Sarah C. Kammerud, Heba A. Alsheikh, Amr Elhamamsy, Dongquan Chen, Victor Darley-Usmar, Jeffrey C. Rathmell, Robert S. Welner, Rajeev S. Samant, Lalita A. Shevde
Publikováno v:
Cancer Immunology Research. 11:687-702
The tumor immune microenvironment dynamically evolves to support tumor growth and progression. Immunosuppressive regulatory T cells (Treg) promote tumor growth and metastatic seeding in patients with breast cancer. Deregulation of plasticity between
Autor:
Wei Yang, Hairong Wei, Gloria A. Benavides, William J. Turbitt, Jessica A. Buckley, Xiaosen Ouyang, Lianna Zhou, Jianhua Zhang, Laurie E. Harrington, Victor M. Darley-Usmar, Hongwei Qin, Etty N. Benveniste
Publikováno v:
The Journal of Immunology. 209:896-906
Protein kinase CK2 is a serine/threonine kinase composed of two catalytic subunits (CK2α and/or CK2α′) and two regulatory subunits (CK2β). CK2 promotes cancer progression by activating the NF-κB, PI3K/AKT/mTOR, and JAK/STAT pathways, and also i
Autor:
Lalita A. Shevde, Rajeev S. Samant, Robert S. Welner, Jeffrey C. Rathmell, Victor Darley-Usmar, Dongquan Chen, Amr Elhamamsy, Heba A. Alsheikh, Sarah C. Kammerud, Courtney A. Swain, Brandon J. Metge, Gloria A. Benavides, Dominique C. Hinshaw
The tumor immune microenvironment dynamically evolves to support tumor growth and progression. Immunosuppressive regulatory T cells (Treg) promote tumor growth and metastatic seeding in patients with breast cancer. Deregulation of plasticity between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bb51e17ee046fee5ad006653e206e9
https://doi.org/10.1158/2326-6066.c.6600106.v2
https://doi.org/10.1158/2326-6066.c.6600106.v2
Autor:
Xiaosen Ouyang, Sayan Bakshi, Gloria A. Benavides, Zhihuan Sun, Gerardo Hernandez‐Moreno, Helen E. Collins, Mariame S. Kane, Silvio Litovsky, Martin E. Young, John C. Chatham, Victor Darley‐Usmar, Adam R. Wende, Jianhua Zhang
Publikováno v:
Physiological Reports. 11