Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Globus Pallidus/diagnostic imaging/metabolism"'
Autor:
Philip Seeman, Irina Vitcu, Pablo Rusjan, Romina Mizrahi, David C. Mamo, Shitij Kapur, Ariel Graff-Guerrero, Nathalie Ginovart, Alan A. Wilson, Matthaeus Willeit
Publikováno v:
Hum Brain Mapp
Human Brain Mapping, Vol. 29, No 4 (2008) pp. 400-10
Human Brain Mapping, Vol. 29, No 4 (2008) pp. 400-10
The D(2) receptors exist in either the high‐ or low‐affinity state with respect to agonists, and while agonists bind preferentially to the high‐affinity state, antagonists do not distinguish between the two states. [(11)C]‐(+)‐PHNO is a PET
Autor:
Ariel Graff, Matthäus Willeit, Nathalie Ginovart, Alan A. Wilson, Irina Vitcu, Pablo Rusjan, Philip Seeman, Sylvain Houle, Shitij Kapur
Publikováno v:
Neuropsychopharmacology, Vol. 33, No 2 (2008) pp. 279-89
Imaging the competition between D(2/3) radioligands and endogenous dopamine is so far the only way to measure dopamine release in the living human brain. The dopamine D(2) receptor exists in a high (D(2)(high)) and a low-affinity state for dopamine.