Zobrazeno 1 - 10
of 5 945
pro vyhledávání: '"Globin gene"'
Autor:
Hossein Jalali, Mohammad Reza Mahdavi, Mehrnoush Kosaryan, Ahmad Najafi, Aily Aliasgharian, Ebrahim Salehifar
Publikováno v:
Thalassemia Reports, Vol 14, Iss 3, Pp 71-80 (2024)
HbF induction is an appropriate strategy to ameliorate the severity of β-thalassemia symptoms. Hydroxyurea (HU) is the most common chemical agent introduced as an HbF inducer but responsiveness to HU is variable and the introduction of HbF inducers
Externí odkaz:
https://doaj.org/article/28040da465084f7b966b7a8289701c21
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Objective The α-globin fusion gene between the HBA2 and HBAP1 genes, is clinically important in thalassemia screening because this fusion gene can cause severe hemoglobin (Hb) H disease when combined with α0 -thalassemia (α0 -thal). In this study,
Externí odkaz:
https://doaj.org/article/0017518e966d434cb72c5d539d4d30aa
Autor:
Cardinale, A.1,2, Fusco, F. R.2, Paldino, E.2, Giampà, C.2,3, Marino, M.1, Nuzzo, M. T.1, D’Angelo, V.4, Laurenti, D.2, Straccia, G.5, Fasano, D.6, Sarnataro, D.6,7, Squillaro, T.5,8, Paladino, S.6,7, Melone, Mariarosa A. B.5,8,9 marina.melone@unicampania.it, D'Angelo, V4 (AUTHOR)
Publikováno v:
Neurological Sciences. Feb2018, Vol. 39 Issue 2, p275-285. 11p. 5 Diagrams.
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 150-156 (2022)
Objectives Shaokwan is one of the inhabitant regions of Hakka population in Guangdong province of southern China. Previous survey has reported that a higher prevalence of abnormal hemoglobin (Hb) in this region. However, large-scale survey on the mol
Externí odkaz:
https://doaj.org/article/ad3758ef68fc462aa8a25c31aedcacff
Autor:
Dormiani, K1, Mir Mohammad Sadeghi, H1, Sadeghi-Aliabadi, H1, Ghaedi, K2, Forouzanfar, M3, Baharvand, H4, Nasr-Esfahani, M H3
Publikováno v:
Gene Therapy. Aug2015, Vol. 22 Issue 8, p663-674. 12p. 1 Color Photograph, 4 Diagrams, 5 Charts, 1 Graph.
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTBackground Thalassemia, a common autosomal hereditary blood disorder worldwide, mainly contains α- and β-thalassemia. The α-globin gene triplicates allele is harmless for carriers, but aggravates the phenotype of β-thalassemia. Therefore,
Externí odkaz:
https://doaj.org/article/7f0792f5951749efaabee65dd3d47f9a
Autor:
Xinxing Xie, Jinhui Gan, Zezhang Liu, Yulian Zhou, Kun Yuan, Zhigang Chen, Shiping Chen, Rui Zhou, Lipei Liu, Xiaoyan Huang, Yan Zhang, Qian Liu, Wenqian Zhang, Jungao Huang, Junkun Chen
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
α-globin gene triplication carriers were not anemic in general, while some studies found that α-globin gene triplication coinherited with heterozygous β-thalassemia may cause adverse clinical symptoms, which yet lacks sufficient evidence in large
Externí odkaz:
https://doaj.org/article/b857fb4c411d43a6a711010b73f9ad80
Autor:
Iarovaia, O. iarovaia@inbox.ru, Ioudinkova, E., Petrova, N., Dolgushin, K. dolgushin-molbiol@bk.ru, Kovina, A.1, Nefedochkina, A.1, Vassetzky, Y., Razin, S.
Publikováno v:
Biochemistry (00062979). Nov2014, Vol. 79 Issue 11, p1141-1150. 10p.
Autor:
Xiuqin Bao, Danqing Qin, Jian Ma, Xiangcheng Zhou, Jicheng Wang, Cuize Yao, Liang Zhang, Li Du
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 198-203 (2022)
Background The α-thalassemia is a highly prevalent disease in tropical and subtropical regions, including southern China, and is mainly caused by deletion in α-globin genes (HBA1 and HBA2). The clinical manifestation of α-thalassemia is highly cor
Externí odkaz:
https://doaj.org/article/7d5df372d2d9410b9fd33815a7b35b16