Nucleotide excision repair: a versatile and smart toolkit

Autor: Zhang Xiping, Yin Mengdie, Hu Jinchuan

Publikováno v: Acta Biochimica et Biophysica Sinica, Vol 54, Pp 807-819 (2022)

Nucleotide excision repair (NER) is a major pathway to deal with bulky adducts induced by various environmental toxins in all cellular organisms. The two sub-pathways of NER, global genome repair (GGR) and transcription-coupled repair (TCR), differ i

Externí odkaz: https://doaj.org/article/4fca01346ae04194a97049a3be5532cf

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Nucleotide excision repair in humans

Autor: Spivak, Graciela ^⁎

Publikováno v: In DNA Repair December 2015 36:13-18

Nucleotide excision repair

Autor: Apelt, K.

Publikováno v: None

This thesis aims to gain a better understanding of NER, to elucidate new molecular mechanisms and proteins that orchestrate how DNA repair is carried out on genomic DNA that is tightly packed in chromatin inside the living cell. It is important to ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::12655344f9035f5e78d61f2bd761e206
https://hdl.handle.net/1887/3283552

Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation

Autor: Benjamin J. Blencowe, Nicolás Nieto Moreno, Manuel J. Muñoz, Carlos Frederico Martins Menck, Gwendal Dujardin, Antonio Torres-Méndez, Marco Foiani, Giulia Bastianello, Manuel Irimia, Stefania Lavore, Alberto R. Kornblihtt, Luciana E. Giono, Adrián E. Cambindo Botto

Publikováno v: Cell Reports, Vol 18, Iss 12, Pp 2868-2879 (2017)
Cell Reports
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

We have previously found that UV irradiation promotes RNA polymerase II (RNAPII) hyperphosphorylation and subsequent changes in alternative splicing (AS). We show now that UV-induced DNA damage is not only necessary but sufficient to trigger the AS r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2496c8aa4df9015da35f37722b6bd015