Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Global genome nucleotide-excision repair"'
Autor:
Elisabetta Bassi, Paola Perucca, Isabella Guardamagna, Ennio Prosperi, Lucia A. Stivala, Ornella Cazzalini
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The Host Cell Reactivation assay (HCR) allows studying the DNA repair capability in different types of human cells. This assay was carried out to assess the ability in removing UV-lesions from DNA, thus verifying NER efficiency. P
Externí odkaz:
https://doaj.org/article/8b41710a9b9e4c5cae43a5c933260ed6
Akademický článek
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Autor:
Diletta Edifizi, Björn Schumacher
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1855-1869 (2015)
DNA damage causally contributes to aging and cancer. Congenital defects in nucleotide excision repair (NER) lead to distinct cancer-prone and premature aging syndromes. The genetics of NER mutations have provided important insights into the distinct
Externí odkaz:
https://doaj.org/article/b7632b0bd0f143cca9922b29bb79ef62
Autor:
Jean Soulier, Alain Sarasin, Ismael Padioleau, Andrey A. Yurchenko, Bakhyt T. Matkarimov, Sergey Nikolaev
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Recent studies demonstrated a dramatically increased risk of leukemia in patients with a rare genetic disorder, Xeroderma Pigmentosum group C (XP-C), characterized by constitutive deficiency of global genome nucleotide excision repair (GG-NER). The g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffce1ef6d3ff6a9db79ece7ca4e4a8d9
http://link.springer.com/article/10.1038/s41467-020-19633-9
http://link.springer.com/article/10.1038/s41467-020-19633-9
Autor:
Kaoru Sugasawa, Mayumi Yuasa-Sunagawa, Masayuki Kusakabe, Wataru Sakai, Masae Ikura, Takeshi Matsui, Masayuki Yokoi, Jun-ichi Akagi, Fumio Hanaoka, Yuki Kaneko, Nicolas Huyghe, Aiko Kishimoto, Tsuyoshi Ikura
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The ubiquitin–proteasome system (UPS) plays crucial roles in regulation of various biological processes, including DNA repair. In mammalian global genome nucleotide excision repair (GG-NER), activation of the DDB2-associated ubiquitin ligase upon U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c5b5d447dfa803577d195b9832b85f
http://link.springer.com/article/10.1038/s41598-020-76898-2
http://link.springer.com/article/10.1038/s41598-020-76898-2
Autor:
Wim Vermeulen, Mariangela Sabatella, Cristina Ribeiro-Silva, Hannes Lans, Arjan F. Theil, Jurgen A. Marteijn, Angela Helfricht
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, 11(1):4868. Nature Publishing Group
Nature Communications
Nature Communications, 11(1):4868. Nature Publishing Group
DNA damage sensors DDB2 and XPC initiate global genome nucleotide excision repair (NER) to protect DNA from mutagenesis caused by helix-distorting lesions. XPC recognizes helical distortions by binding to unpaired ssDNA opposite DNA lesions. DDB2 bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af01a3689cd4ddf47e112ea7ae83b16
https://doaj.org/article/22a70086ef524db897815d6000e52c4e
https://doaj.org/article/22a70086ef524db897815d6000e52c4e
Autor:
Hu Zhang, Alexander L. Marchetti, Sunbok Jang, Mu Wang, Haitao Guo, Xiaoyang Yu, Elena S. Kim
Publikováno v:
J Virol
Hepatitis B virus (HBV) utilizes host DNA repair mechanisms to convert viral relaxed circular DNA (rcDNA) into a persistent viral genome, the covalently closed circular DNA (cccDNA). To identify host factors involved in cccDNA formation, we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49eefd108d3b9b5b207c7a062d0d8ae9
https://doi.org/10.1128/jvi.01360-21
https://doi.org/10.1128/jvi.01360-21
Autor:
Frédéric Mazurier, Kazem Zibara, Abir Zebian, Maya El-Dor, Hamid Reza Rezvani, Abdullah Shaito
Publikováno v:
Mutation Research-Reviews
Mutation Research-Reviews, 2022, 789, pp.108400. ⟨10.1016/j.mrrev.2021.108400⟩
Mutation Research-Reviews, 2022, 789, pp.108400. ⟨10.1016/j.mrrev.2021.108400⟩
International audience; Xeroderma pigmentosum group C protein (XPC) acts as a DNA damage recognition factor for bulky adducts and as an initiator of global genome nucleotide excision repair (GG-NER). Novel insights have shown that the role of XPC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a2a08eb8ab649c0c147d3b627134fb
https://hdl.handle.net/10576/25608
https://hdl.handle.net/10576/25608
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 78(24), 7925-7942. SPRINGER BASEL AG
Cellular and Molecular Life Sciences, 78(24), 7925-7942. SPRINGER BASEL AG
Global genome nucleotide excision repair (GG-NER) eliminates a broad spectrum of DNA lesions from genomic DNA. Genomic DNA is tightly wrapped around histones creating a barrier for DNA repair proteins to access DNA lesions buried in nucleosomal DNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116c73b2d03d4237c0a151294050a943
https://hdl.handle.net/1887/3250044
https://hdl.handle.net/1887/3250044
Autor:
Hilda Stekman, Annika Karger, Carla M. Farah, Michael Kracht, Susanne Bacher, M. Lienhard Schmitz
Publikováno v:
Molecular and Cellular Biology
Cullin-4 ubiquitin ligase (CRL4) complexes are differentially composed and highly dynamic protein assemblies that control many biological processes, including the global genome nucleotide excision repair (GG-NER) pathway. Here, we identified the kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4175d720135f813d71fe99c53b11fa
http://europepmc.org/articles/PMC8462458
http://europepmc.org/articles/PMC8462458