Zobrazeno 1 - 10 of 47 pro vyhledávání: '"Gln, glutamine"'
1
In silico study reveals binding potential of rotenone at multiple sites of pulmonary surfactant proteins: A matter of concern
Autor: Prem Rajak, Sumedha Roy, Achintya Kumar Pal, Manas Paramanik, Moumita Dutta, Sayanti Podder, Saurabh Sarkar, Abhratanu Ganguly, Moutushi Mandi, Anik Dutta, Kanchana Das, Siddhartha Ghanty, Salma Khatun
Publikováno v: Current Research in Toxicology, Vol 2, Iss, Pp 411-423 (2021)
Current Research in Toxicology
CURRENT RESEARCH IN TOXICOLOGY
Graphical abstract
Highlights • Inhalation of rotenone exposes lung surfactant proteins (SP) to this pesticide. • SP-A and SP-D provides protection from microbial infection. • SP-B and SP-C maintain structure and respiratory function of lu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f2cd79baf46b999beeed39c977274d
http://www.sciencedirect.com/science/article/pii/S2666027X21000414
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2
Advances in flux balance analysis by integrating machine learning and mechanism-based models
Autor: Ankur Sahu, Nadine Töpfer, Jedrzej Szymanski, Mary Ann Blätke
Publikováno v: Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4626-4640 (2021)
Computational and Structural Biotechnology Journal
Computational and structural biotechnology journal, 19:4626-4640
Graphical abstract
The availability of multi-omics data sets and genome-scale metabolic models for various organisms provide a platform for modeling and analyzing genotype-to-phenotype relationships. Flux balance analysis is the main tool for pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7b26546e5e7987f341a45a4a22a623
https://doi.org/10.1016/j.csbj.2021.08.004
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3
Regulation of hepatic glutamine metabolism by miR-122
Autor: Teresa W.-M. Fan, Xiaoli Zhang, Teresa Cassel, Kalpana Ghoshal, Kun-Yu Teng, Vivek Chowdhary, Peng Hu, Dipanwita Sengupta, Mona Aljuhani
Publikováno v: Molecular Metabolism
Molecular Metabolism, Vol 34, Iss, Pp 174-186 (2020)
Objective It is well established that the liver-specific miR-122, a bona fide tumor suppressor, plays a critical role in lipid homeostasis. However, its role, if any, in amino acid metabolism has not been explored. Since glutamine (Gln) is a critical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7afcb99de07d714db8184aca0e22eb0
https://doi.org/10.1016/j.molmet.2020.01.003
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4
Sex-specific metabolic alterations in the type 1 diabetic brain of mice revealed by an integrated method of metabolomics and mixed-model
Autor: Hongchang Gao, Liangcai Zhao, Qingqing Xu, Junjie Yan, Yafei Zheng, Hangying Xu, Chen Li, Qiaoying Jiang, Hong Zheng
Publikováno v: Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2063-2074 (2020)
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • Sex-specific metabolic differences occur in all brain regions of mice. • The hippocampal metabolism is more susceptible to T1D. • Metabolic disorders start at the cortex and hippocampus in female T1D mice.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f4f182a76ce782a14533b123602dc5
http://www.sciencedirect.com/science/article/pii/S2001037020303512
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5
Clinical utility of brain MRS imaging of patients with adult-onset non-cirrhotic hyperammonemia
Autor: Gerard T. Berry, Joel B. Krier, Andrew B. Stergachis, Sai Merugumala, Alexander P. Lin
Publikováno v: Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 27, Iss, Pp 100742-(2021)
Adult-onset non-cirrhotic hyperammonemia (NCH) is a rare, but often fatal condition that can result in both reversible and irreversible neurological defects. Here we present five cases of adult-onset non-cirrhotic hyperammonemia wherein brain magneti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d8daedaad9a702f2ceecfe4d789ba2
http://europepmc.org/articles/PMC7973242
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6
Dietary hydrolyzed wheat gluten supplementation ameliorated intestinal barrier dysfunctions of broilers challenged with Escherichia coli O78
Autor: In Ho Kim, Yujun Wu, Ying Yang, Wenyu Wang
Publikováno v: Poultry Science
Poultry Science, Vol 101, Iss 2, Pp 101615-(2022)
This study aimed to investigate a protective effect of hydrolyzed wheat gluten (HWG) on Escherichia coli (E. coli)-induced intestinal barrier dysfunctions in broilers. Broilers fed a basal diet unsupplemented or supplemented with HWG (0.5% or 1%) wer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fb0d0f6b508721a84b1f822287ef4b
https://pubmed.ncbi.nlm.nih.gov/34952261
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7
Impaired beta-oxidation increases vulnerability to influenza A infection
Autor: Klaus Schughart, Diana Cabrera, Heike Kollmus, Carolin Pilzner, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez
Publikováno v: The Journal of biological chemistry
United States
The Journal of Biological Chemistry
Influenza A virus (IAV) infection casts a significant burden on society. It has particularly high morbidity and mortality rates in patients suffering from metabolic disorders. The aim of this study was to relate metabolic changes with IAV susceptibil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35df79d0e1826add7a81f0ba6216551f
https://hdl.handle.net/10033/623093
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8
Phytoconstituents from ten natural herbs as potent inhibitors of main protease enzyme of SARS-COV-2: in silico study
Autor: Kavita Bhagat, Preet Mohinder Singh Bedi, Atamjit Singh, Amit Duggal, Puja Gulati, Komalpreet Kaur, Shilpa Dudhal, Harmandeep Kaur Gulati, Jatinder Vir Singh, Jaspreet Kaur, Harbinder Singh, Nitish Kumar
Publikováno v: Phytomedicine Plus
Phytomedicine Plus, Vol 1, Iss 4, Pp 100083-(2021)
Background Lack of treatment of novel Coronavirus disease led to the search of specific antivirals that are capable to inhibit the replication of the virus. The plant kingdom has demonstrated to be an important source of new molecules with antiviral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939ef681815567886f1f3e386c85714b
http://europepmc.org/articles/PMC8180089
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9
High-resolution metabolic imaging of high-grade gliomas using 7T-CRT-FID-MRSI
Autor: Hangel, Gilbert, Cadrien, Cornelius, Lazen, Philipp, Furtner, Julia, Lipka, Alexandra, Hečková, Eva, Hingerl, Lukas, Motyka, Stanislav, Gruber, Stephan, Strasser, Bernhard, Kiesel, Barbara, Mischkulnig, Mario, Preusser, Matthias, Roetzer, Thomas, Wöhrer, Adelheid, Widhalm, Georg, Rössler, Karl, Trattnig, Siegfried, Bogner, Wolfgang
Publikováno v: NeuroImage: Clinical, Vol 28, Iss, Pp 102433-(2020)
NeuroImage : Clinical
Graphical abstract
Highlights • We demonstrated reliable and fast whole-brain 3D-MRSI of high-grade gliomas at 7T. • tCho, Gln, and Gly were increased in contrast-enhancing tumor tissue. • Results corresponded well to clinical data, but sh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28bb3c72f0f60bade3cf746269e3a9c2
http://www.sciencedirect.com/science/article/pii/S2213158220302709
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10
Brain edema in chronic hepatic encephalopathy
Autor: Simon D. Taylor-Robinson, Cristina Cudalbu
Publikováno v: Journal of Clinical and Experimental Hepatology
Brain edema is a common feature associated with hepatic encephalopathy (HE). In patients with acute HE, brain edema has been shown to play a crucial role in the associated neurological deterioration. In chronic HE, advanced magnetic resonance imaging
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a25552f9b461db89c96ba1fe0965774
http://hdl.handle.net/10044/1/69654
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