Mechanistic basis for the emergence of EPS1 as a catalyst in salicylic acid biosynthesis of Brassicaceae.

Autor: Torrens-Spence MP; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Matos JO; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Institute for Plant-Human Interface, Northeastern University, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Department of Bioengineering, and Department of Chemical Engineering, Northeastern University, Boston, MA, USA., Li T; Department of Physics, The Chinese University of Hong Kong, Hong Kong, P. R. China., Kastner DW; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Kim CY; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA., Wang Z; Department of Physics, The Chinese University of Hong Kong, Hong Kong, P. R. China., Glinkerman CM; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Sherk J; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Institute for Plant-Human Interface, Northeastern University, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Department of Bioengineering, and Department of Chemical Engineering, Northeastern University, Boston, MA, USA., Kulik HJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Wang Y; Department of Physics, The Chinese University of Hong Kong, Hong Kong, P. R. China., Weng JK; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. jingke.weng@northeastern.edu.; Institute for Plant-Human Interface, Northeastern University, Boston, MA, USA. jingke.weng@northeastern.edu.; Department of Chemistry and Chemical Biology, Department of Bioengineering, and Department of Chemical Engineering, Northeastern University, Boston, MA, USA. jingke.weng@northeastern.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 28; Vol. 15 (1), pp. 10356. Date of Electronic Publication: 2024 Nov 28.

Sporopollenin-inspired design and synthesis of robust polymeric materials.

Autor: Glinkerman CM; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA., Lin S; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Ni J; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Li FS; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA., Zhao X; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Weng JK; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA. wengj@wi.mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. wengj@wi.mit.edu.

Publikováno v: Communications chemistry [Commun Chem] 2022 Sep 12; Vol. 5 (1), pp. 110. Date of Electronic Publication: 2022 Sep 12.

Selective N1/N4 1,4-Cycloaddition of 1,2,4,5-Tetrazines Enabled by Solvent Hydrogen Bonding.

Autor: Zhu Z; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States., Glinkerman CM; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States., Boger DL; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2020 Dec 09; Vol. 142 (49), pp. 20778-20787. Date of Electronic Publication: 2020 Nov 30.

Precise Targeted Cleavage of a r(CUG) Repeat Expansion in Cells by Using a Small-Molecule-Deglycobleomycin Conjugate.

Autor: Angelbello AJ; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States., DeFeo ME; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States., Glinkerman CM; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States., Boger DL; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States., Disney MD; Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2020 Apr 17; Vol. 15 (4), pp. 849-855. Date of Electronic Publication: 2020 Mar 18.

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes.

Autor: Ozog S; The Scripps Research Institute, La Jolla, CA., Timberlake ND; The Scripps Research Institute, La Jolla, CA.; Poseida Therapeutics, San Diego, CA., Hermann K; The Scripps Research Institute, La Jolla, CA., Garijo O; The Scripps Research Institute, La Jolla, CA., Haworth KG; Fred Hutchinson Cancer Research Center, Seattle, WA., Shi G; National Cancer Institute, Frederick, MD., Glinkerman CM; The Scripps Research Institute, La Jolla, CA., Schefter LE; Fred Hutchinson Cancer Research Center, Seattle, WA., D'Souza S; Wisconsin National Primate Research Center, Madison, WI., Simpson E; The Scripps Research Institute, La Jolla, CA., Sghia-Hughes G; Fred Hutchinson Cancer Research Center, Seattle, WA., Carillo RR; Fred Hutchinson Cancer Research Center, Seattle, WA., Boger DL; The Scripps Research Institute, La Jolla, CA., Kiem HP; Fred Hutchinson Cancer Research Center, Seattle, WA.; University of Washington, Seattle, WA., Slukvin I; Wisconsin National Primate Research Center, Madison, WI., Ryu BY; St. Jude Children's Research Hospital, Memphis, TN., Sorrentino BP; St. Jude Children's Research Hospital, Memphis, TN., Adair JE; Fred Hutchinson Cancer Research Center, Seattle, WA.; University of Washington, Seattle, WA., Snyder SA; The Scripps Research Institute, Jupiter, FL; and.; University of Chicago, Chicago, IL., Compton AA; National Cancer Institute, Frederick, MD., Torbett BE; The Scripps Research Institute, La Jolla, CA.

Publikováno v: Blood [Blood] 2019 Oct 17; Vol. 134 (16), pp. 1298-1311.