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CIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1

Autor: Andrew Ruszkiewicz, Stuart M. Pitson, Jason A. Powell, Briony L. Gliddon, Wenying Zhu, T. Tin, Melissa R. Pitman, Paul A.B. Moretti, Leslie V. Parise, Joanna M. Woodcock, Kate E. Jarman

Publikováno v: Oncogene

CIB1 (calcium and integrin binding protein 1) is a small intracellular protein with numerous interacting partners, and hence has been implicated in various cellular functions. Recent studies have revealed emerging roles of CIB1 in regulating cancer c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be23fab4e90662f181b3b3c4d46768b
https://hdl.handle.net/11541.2/123598

An orthotopic syngeneic mouse model of bortezomib-resistant multiple myeloma.

Autor: Li M; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Bennett MK; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Toubia J; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Pope VS; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Tea MN; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Tamang S; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Samuel MS; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia., Anderson PH; Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia., Gliddon BL; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia., Powell JA; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia., Pitson SM; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.; School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.

Publikováno v: British journal of haematology [Br J Haematol] 2024 Feb; Vol. 204 (2), pp. 566-570. Date of Electronic Publication: 2023 Dec 05.

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.

Autor: Lewis AC; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Pope VS; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Tea MN; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Li M; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Nwosu GO; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Nguyen TM; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Wallington-Beddoe CT; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.; Flinders Medical Centre, Bedford Park, SA, Australia., Moretti PAB; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Anderson D; Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Creek DJ; Drug Delivery, Disposition, and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Costabile M; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia., Ali SR; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Thompson-Peach CAL; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Dredge BK; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Bert AG; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Goodall GJ; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Ekert PG; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia., Brown AL; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, SA, Australia., D'Andrea R; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Robinson N; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Pitman MR; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia., Thomas D; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford University, Stanford, CA; and., Ross DM; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.; Flinders Medical Centre, Bedford Park, SA, Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Department of Haematology and Bone Marrow Transplantation, Royal Adelaide Hospital, Adelaide, SA, Australia., Gliddon BL; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Powell JA; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Pitson SM; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Faculty of Health Sciences, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.

Publikováno v: Blood [Blood] 2022 Jun 30; Vol. 139 (26), pp. 3737-3751.

Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion.

Autor: Duszyc K; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Gomez GA; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Lagendijk AK; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Yau MK; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia; Centre for Inflammation and Disease Research, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia; ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Nanavati BN; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Gliddon BL; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5000, Australia., Hall TE; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Verma S; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Hogan BM; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Pitson SM; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5000, Australia., Fairlie DP; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia; Centre for Inflammation and Disease Research, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia; ARC Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Parton RG; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Yap AS; Division of Cell and Developmental Biology, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia. Electronic address: a.yap@uq.edu.au.

Publikováno v: Current biology : CB [Curr Biol] 2021 Mar 22; Vol. 31 (6), pp. 1326-1336.e5. Date of Electronic Publication: 2021 Feb 12.