Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Glial cell differentiation"'
Publikováno v:
Stem Cells and Development. 31:741-755
Hedgehog signaling is essential for vertebrate development, however, less is known about the negative regulators that influence this pathway during the differentiation of cell fates. Using the mouse P19 embryonal carcinoma cell model, Suppressor of F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30aa64f07490587e3015df6ec26b33cb
https://doi.org/10.1089/scd.2022.0131
https://doi.org/10.1089/scd.2022.0131
Autor:
Zhongming Zhao, Shan Jiang, Gabriel Rodrigo Fries, Consuelo Walss-Bass, Yulin Dai, Thomas Meyer, Ruifeng Hu, Emily Mendez, Andi Liu, Peilin Jia, Katherine Najera, Laura Stertz
Publikováno v:
International Journal of Neuropsychopharmacology
Background Opioid use disorder (OUD) affects millions of people, causing nearly 50 000 deaths annually in the United States. While opioid exposure and OUD are known to cause widespread transcriptomic and epigenetic changes, few studies in human sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d14ce7d85842b022f4dd0d9c8c9eab
http://europepmc.org/articles/PMC8598308
http://europepmc.org/articles/PMC8598308
Autor:
Yoshio Goshima, Ayaka Sugeno, Kiyofumi Takahashi, Miki Yamazaki, Masahito Hosokawa, Koji Arikawa, Wenhui Piao, Daisuke Tominaga, Hiroko Matsunaga, Haruko Takeyama, Toshio Ohshima
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 16, Iss 7, Pp 1258-1265 (2021)
Neural Regeneration Research, Vol 16, Iss 7, Pp 1258-1265 (2021)
Recent studies have shown that mutation at Ser522 causes inhibition of collapsin response mediator protein 2 (CRMP2) phosphorylation and induces axon elongation and partial recovery of the lost sensorimotor function after spinal cord injury (SCI). We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff26e0405632d058530eb1db7dbf719
http://europepmc.org/articles/PMC8284262
http://europepmc.org/articles/PMC8284262
Publikováno v:
Genes
Genes, Vol 12, Iss 1363, p 1363 (2021)
Volume 12
Issue 9
Genes, Vol 12, Iss 1363, p 1363 (2021)
Volume 12
Issue 9
Maternal immune activation (MIA) is a known risk factor for schizophrenia (SCZ) and autism spectrum disorder (ASD) and is often modelled in animal studies in order to study the effect of prenatal infection on brain function including behaviour and ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039da48590d01d5a093bfc57911492aa
https://pubmed.ncbi.nlm.nih.gov/34573345
https://pubmed.ncbi.nlm.nih.gov/34573345
Publikováno v:
Neuropharmacology. 148:31-39
Organophosphorus compound (OP)-induced delayed neuropathy (OPIDN) is characterized by distal axonal degeneration and demyelination of the central and peripheral axons, which leads to progressive muscle weakness, ataxia and paralysis in several days a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beeb63315442db2b0370b72eb799248e
https://doi.org/10.1016/j.neuropharm.2018.12.015
https://doi.org/10.1016/j.neuropharm.2018.12.015
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Stem Cells International
Stem Cells International
The RNA-binding protein Lin28 regulates neurogliogenesis in mammals, independently of the let-7 microRNA. However, the detailed regulatory mechanism remains obscured. Here, we established Lin28a or Lin28b overexpression mouse embryonic stem cells (ES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e33e6753846ee6b060c31f1ffdc62e
https://doaj.org/article/59ff01503a9d47b798f2286f79898dcd
https://doaj.org/article/59ff01503a9d47b798f2286f79898dcd
Autor:
Jennifer B. Green, Svati H. Shah, Robert W. McGarrah, Maggie Nguyen, Stephani Giamberardino, Eberhard Standl, Rury R. Holman, Robert J. Mentz, Lauren K Truby, Jessica A Regan, Darren K. McGuire, Paul W. Armstrong, John B. Buse, Eric D. Peterson, Yinggan Zheng
Publikováno v:
Circulation. 142
Introduction: To date, there are limited data on the potential role of proteomic biomarkers to predict future cardiovascular (CV) events among patients with type 2 diabetes mellitus (DM). Hypothesis: Specific protein biomarkers will be predictive of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83c9066e9361327f9c1c100062d9c5bd
https://doi.org/10.1161/circ.142.suppl_3.14727
https://doi.org/10.1161/circ.142.suppl_3.14727
Autor:
Cheol-Hee Kim, Seung-Tae Lee, Joon Soo Lee, Juneyong Eum, Hoon Chul Kang, Se Hee Kim, Bonsu Ku, Kang-Han Lee, Joshua L. Bonkowsky, Yun Kee, Tae-Ik Choi, Sangkyu Lee, Hyung-Goo Kim, Afif Ben-Mahmoud, Yu-Ri Lee, Oc-Hee Kim, Jihoon Cha, Heung Dong Kim, Dongju Won, Jong Rak Choi
Publikováno v:
Human molecular genetics. 30(5)
Leukodystrophy with vanishing white matter (VWM), also called Childhood Ataxia with Central Nervous System Hypomyelination, is caused by mutations in the subunits of the eukaryotic translation initiation factor, EIF2B1, EIF2B2, EIF2B3, EIF2B4 or EIF2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4059e515ce5995c6f54c4594f909465a
https://pubmed.ncbi.nlm.nih.gov/33517449
https://pubmed.ncbi.nlm.nih.gov/33517449
Autor:
Nadia Al-Sammarraie, Swapan K. Ray
Publikováno v:
Neuroimmunology and neuroinflammation
Spinal cord injury (SCI) is a debilitating injury that results from traumatic or non-traumatic insults to the spinal cord, causing significant impairment of the patient’s activity and quality of life. Bone morphogenic proteins (BMPs) are a group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce0e8a93cacc7a66d3b53449aeddaa8
https://doi.org/10.20517/2347-8659.2020.34
https://doi.org/10.20517/2347-8659.2020.34
Autor:
Taida Huang, Nan Wang, Chenju Yi, Zitian Wang, Yunxin Zeng, Yixun Su, Zhangsen Huang, Hui Chen, Huaxun Fan, Kai Zhang, Xiaomin Huang, Yan Zhang
Publikováno v:
Advanced biology. 5(5)
Hair-follicle-derived stem cells (HSCs) originating from the bulge region of the mouse vibrissa hair follicle are able to differentiate into neuronal and glial lineage cells. The tropomyosin receptor kinase A (TrkA) receptor that is expressed on thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a6356a06e96cd0b5651e91de54c89a
https://pubmed.ncbi.nlm.nih.gov/32924336
https://pubmed.ncbi.nlm.nih.gov/32924336