Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Glial Cell Line-Derived Neurotrophic Factor/genetics"'
Autor:
Virginie Zimmer, Sebastian Kügler, Shi Cheng, Frank Streit, Catherine Pythoud, Jolanda M. Liefhebber, Anupam Raina, Pavlina Konstantinova, Nicole Déglon, Maria Rey, Gabriel Vachey, Julia Tereshchenko, Andrzej Mazur, Mathias Bähr
Publikováno v:
Experimental neurology, vol. 309, pp. 79-90
Gene therapy is currently an irreversible approach, without possibilities to fine-tune or halt the expression of a therapeutic gene product. Especially when expressing neurotrophic factors to treat neurodegenerative disorders, options to regulate tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6bc910cb868b3ba3bfa0229d4aa882
https://doi.org/10.1016/j.expneurol.2018.07.017
https://doi.org/10.1016/j.expneurol.2018.07.017
Autor:
Liliane Tenenbaum, Abdelwahed Chtarto, Janica Wakkinen, Xin Yang, Olivier Bockstael, Catherine Melas, Jacques Brotchi, Marc Levivier
Publikováno v:
Human Gene Therapy, vol. 19, no. 11, pp. 1293-1305
The biodistribution of transgene expression in the CNS after localized stereotaxic vector delivery is an important issue for the safety of gene therapy for neurological diseases. The cellular specificity of transgene expression from rAAV2/1 vectors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8024f2594b40a14eda79fbe8daedd8e
https://pubmed.ncbi.nlm.nih.gov/19866492
https://pubmed.ncbi.nlm.nih.gov/19866492