Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Glenroy D. A. Martin"'
Publikováno v:
Natural product communications. 12(4)
Hydrogenation of curcumin (1), a chemopreventive agent from Turmeric ( Curcuma longa L.) yielded three major compounds: 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione (2), 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one (3), and 1,7-bis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7de75ca895ea144088343a2dfce0f5c
https://pubmed.ncbi.nlm.nih.gov/30520596
https://pubmed.ncbi.nlm.nih.gov/30520596
Publikováno v:
Steroids. 113:95-102
Bioconversion of the aromatase inhibitor formestane (4-hydroxyandrost-4-ene-3,17-dione) (1) by the fungus Rhizopus oryzae ATCC 11145 resulted in a new minor metabolite 3,5α-dihydroxyandrost-2-ene-4,17-dione (2) and the known 4β,5α-dihydroxyandrost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a5c2efca997a9bb9ac9421a6d5cf20
https://doi.org/10.1016/j.steroids.2016.07.003
https://doi.org/10.1016/j.steroids.2016.07.003
Autor:
Glenroy D. A. Martin, Anna Christensen
Publikováno v:
MicrobiologyOpen
The ocean, with its rich untapped chemical biodiversity, continues to serve as a source of potentially new therapeutic agents. The evaluation of the diversity of cultivable microorganisms from the marine sponge Halichondria panicea and ocean sediment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86cccd0d2344501089dd726313f3d97
https://doi.org/10.1002/mbo3.448
https://doi.org/10.1002/mbo3.448
Publikováno v:
Journal of Natural Products. 76:1966-1969
In an effort to generate new steroidal aromatase inhibitors, formestane (4-hydroxyandrost-4-ene-3,17-dione) (1) was biotransformed by Rhizopus oryzae to yield the known 4β,5α-dihydroxyandrostane-3,17-dione as the major product (5) and bioconverted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e6ff7e14c4b7be3854295822a2b524
https://doi.org/10.1021/np400585t
https://doi.org/10.1021/np400585t
Autor:
Glenroy D. A. Martin
Publikováno v:
Current Organic Chemistry. 14:1-14
The Rhizopus spp., in particular Rhizopus oryzae, are among the most frequently used whole cell biocatalysts. The fungus is known to catalyze the bioconversion of various reactive and non-reactive substrates with high regio- and stereoselectivities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5043fac34c4dba3ea01d5e70e0fc7868
https://doi.org/10.2174/138527210790226438
https://doi.org/10.2174/138527210790226438
Publikováno v:
Journal of Theoretical and Computational Chemistry. :421-433
An active site model for generic hydroxylation of xenobiotes by the fungus Rhizopus oryzae ATCC 11145 has been developed. The model was constructed using data from known metabolites of R. oryzae, as reported in the chemical literature, including dite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3193496d4906fd80c94e7d2c86df130e
https://doi.org/10.1142/s0219633608003885
https://doi.org/10.1142/s0219633608003885
Autor:
Rosalba Encarnacion Dimayuga, Lik Tong Tan, William Fenical, Carmen Raventos-Suarez, Glenroy D. A. Martin, Paul R. Jensen, Craig R. Fairchild
Publikováno v:
Journal of Natural Products. 70:1406-1409
Two new cytotoxic quinones of the angucycline class, marmycins A and B ( 1, 2), were isolated from the culture broth of a marine sediment-derived actinomycete related to the genus Streptomyces. The gross structures and absolute configurations of both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8723feb87a5423657e8074a34b7a5b6b
https://doi.org/10.1021/np060621r
https://doi.org/10.1021/np060621r
Publikováno v:
Phytochemistry. 65:2211-2217
Incubation of 2α,13( R )-dihydroxystemodane ( 3 ) with Rhizopus oryzae ATCC 11145 gave 2α,7β,13( R )-trihydroxystemodane ( 11 ) while biotransformation of 13( R )-hydroxystemodan-2-one ( 5 ) yielded 6α,13( R )-dihydroxystemodan-2-one ( 12 ) and 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2539f30b98ef52e26f182d0f57f08330
https://doi.org/10.1016/j.phytochem.2004.05.016
https://doi.org/10.1016/j.phytochem.2004.05.016
Publikováno v:
Natural product communications. 4(6)
This is the first report of a phytochemical investigation of Jamaican populations of a local folk medicinal plant Salvia coccinea (Lamiaceae/Labiatae). Apart from the presence of 3-sitosterol, phytochemical profiling of the aerial parts yielded compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e945704e735ac8537e9f2315f7c8fd0
https://pubmed.ncbi.nlm.nih.gov/19634323
https://pubmed.ncbi.nlm.nih.gov/19634323
Publikováno v:
Phytochemistry. 66(8)
Solvolytic rearrangement of the C/D ring system of the tetracyclic diterpenoid stemodinone (2) afforded the compounds 15(13--12)abeo-13beta-hydroxystemaran-2-one (5) and 15(8--9)abeo-8beta(H)-12beta-hydroxystachan-2-one (10). Terpene 5 possesses a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734616ad314428034b63f8adcd53d451
https://pubmed.ncbi.nlm.nih.gov/15845408
https://pubmed.ncbi.nlm.nih.gov/15845408