Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Glenn Yiu"'
Autor:
Arina Nisanova, BA, Ashutosh Parajuli, BS, Bhavna Antony, PhD, Orwa Aboud, MD, PhD, Jinger Sun, MD, PhD, Megan E. Daly, MD, Ruben C. Fragoso, MD, PhD, Glenn Yiu, MD, PhD, Yin Allison Liu, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 6, Pp 100577- (2024)
Purpose: To determine whether microstructural retinal changes, tumor features, and apolipoprotein E (APOE) ε4 polymorphism are correlated with clinically detectable treatment-associated cognitive dysfunction (TACD) in patients with lower-grade gliom
Externí odkaz:
https://doaj.org/article/1014659aa7ba49f09473036a3135bf1b
Autor:
Arina Nisanova, BA, Arefeh Yavary, MSc, Jordan Deaner, MD, Ferhina S. Ali, MD, MPH, Priyanka Gogte, MD, Richard Kaplan, MD, Kevin C. Chen, MD, Eric Nudleman, MD, PhD, Dilraj Grewal, MD, Meenakashi Gupta, MD, Jeremy Wolfe, MD, Michael Klufas, MD, Glenn Yiu, MD, PhD, Iman Soltani, PhD, Parisa Emami-Naeini, MD, MPH
Publikováno v:
Ophthalmology Science, Vol 4, Iss 5, Pp 100470- (2024)
Purpose: Automated machine learning (AutoML) has emerged as a novel tool for medical professionals lacking coding experience, enabling them to develop predictive models for treatment outcomes. This study evaluated the performance of AutoML tools in d
Externí odkaz:
https://doaj.org/article/15a7f54b929744708a86d399eab9496a
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25845- (2024)
Purpose: Timely diagnosis of diabetic retinopathy is important in preventing vision loss. This study aims to determine if remote retinal imaging enables earlier eye care access among newly-diagnosed diabetic patients. Design: Retrospective cohort stu
Externí odkaz:
https://doaj.org/article/a62515e1dbc340e1b2950fbe3e7d9b16
Autor:
Sook Hyun Chung, Tzu-Ni Sin, Brian Dang, Taylor Ngo, Therlinder Lo, Daniella Lent-Schochet, Ratheesh K. Meleppat, Robert J. Zawadzki, Glenn Yiu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 613-622 (2022)
Clustered regularly interspaced short palindromic repeats (CRISPR)-based genomic disruption of vascular endothelial growth factor A (Vegfa) with a single gRNA suppresses choroidal neovascularization (CNV) in preclinical studies, offering the prospect
Externí odkaz:
https://doaj.org/article/bfb44be0cc0747e8bd3c8d258b7ce193
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 27, Iss , Pp 101613- (2022)
Purpose: To illustrate the importance of systemic evaluation in retinal dystrophies through examples of Alstrom syndrome, Bardet Biedl syndrome, and Refsum disease. Observations: Detailed eye evaluations, including visual acuity, visual field, slit l
Externí odkaz:
https://doaj.org/article/dbb2179bcfca475c8c18d5c90a54adf6
Autor:
Sook Hyun Chung, Iris Natalie Mollhoff, Uyen Nguyen, Amy Nguyen, Natalie Stucka, Eric Tieu, Suman Manna, Ratheesh Kumar Meleppat, Pengfei Zhang, Emerald Lovece Nguyen, Jared Fong, Robert Zawadzki, Glenn Yiu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 409-417 (2020)
Frequent injections of anti-vascular endothelial growth factor (anti-VEGF) agents are a clinical burden for patients with neovascular age-related macular degeneration (AMD). Genomic disruption of VEGF-A using adeno-associated viral (AAV) delivery of
Externí odkaz:
https://doaj.org/article/fcf7aef49a2349ed9ced422596669c24
Autor:
Glenn Yiu, Sook Hyun Chung, Iris N. Mollhoff, Uyen Tu Nguyen, Sara M. Thomasy, Jesse Yoo, Donna Taraborelli, Glenn Noronha
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 16, Iss , Pp 179-191 (2020)
Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery an
Externí odkaz:
https://doaj.org/article/43af1bbe86bd407695b7807901aa2def
Publikováno v:
Journal of Ophthalmology, Vol 2022 (2022)
Purpose. Evaluate the relationship between retinal vascular caliber and age-related macular degeneration (AMD) severity or progression. Methods. A retrospective secondary analysis of 1172 fundus photographs and clinical data from the prospective Age-
Externí odkaz:
https://doaj.org/article/84c3e6cb8dd643788705ce37ec33844a
Publikováno v:
American Journal of Ophthalmology. 249:74-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab0444fc0dca1de451bd3e600ac4862
https://doi.org/10.1016/j.ajo.2023.01.004
https://doi.org/10.1016/j.ajo.2023.01.004
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
Among genome engineering tools, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-based approaches have been widely adopted for translational studies due to their robustness, precision, and ease of use. When delivered to diseased tis
Externí odkaz:
https://doaj.org/article/0199719195ee4b56970bc6f4a55dba00